Binita Kane Profile picture
Aug 7 5 tweets 3 min read
Very interesting story of Dr Alice Stewart and Sir Richard Doll.

Dr Stewart first discovered the association between X-raying pregnant women and the risk of developing childhood cancer. Her work was ‘debunked’ by a prominent epidemiologist Sir Richard Doll /1
Dr Stewart doubted herself but the evidence was there loud and clear. The damage that Doll had done with opposition took years to unravel. Meanwhile thousands of childhood cancers could have been avoided.
Why? ‘Her findings undermined the prevailing mental model of disease’ 3/
‘She had to be wrong. If she was right, too many other assumptions had to be re-examined.’

‘What Dr Stewart had provoked in her scientific colleagues was cognitive dissonance: the mental turmoil that is evoked when the mind tries to hold 2 entirely’ incompatible views’. 4/
It turns out that Sir Richard Doll had all sorts of conflicts of interest including taking large sums of money from industries whose chemicals he was clearing of cancer risk. Read more here;
/5

pubmed.ncbi.nlm.nih.gov/22019537/
A huge thank you to @amirhannan for recommending @M_Heffernan’s book #wilfulblindness which has many of these stories and is giving me lots of food for thought - including exploring my own biases in more detail. Highly recommended reading in the current world we live in (6/6)

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More from @BinitaKane

Jul 23
Schools Unions have written to The Secretary of State outlining an urgent need for a summer action plan to prevent a winter of disruption due to #COVID19 in schools. Measures they are calling for are; 🧵
1/ Provide additional funding to schools to improve ventilation.

This will help not only reduce spread of #COVID19 but also reduce the impact of #airpollution which is harming our kids' health in multiple ways.
2/ Provide HEPA air filtration devices to all schools for September as an immediate measure while schools improve their ventilation.

Sensible strategy as improving ventilation takes time and we need to keep children safe in the interim.
Read 11 tweets
Jul 7
My husband has tested positive for COVID this week. The mystery of the ‘gastro bug’ we’ve had has been solved…mine and J’s LFTs were neg, but husband couldn’t have got it anywhere else other than the house 1/
On Monday he wasn’t feeling great but went to the school production. He was LFT neg but wore an FFP2 mask throughout. I also emailed school in the morning to ensure the doors would be open to ventilate the hall (they were). Hopefully no-one else was put at risk 2/
Jasmin had removed her FFP2 in school for the rehearsals of the production. I’m pretty sure that’s where she picked it up. No HEPAs in the hall, lots of singing and shouting at close range. I then looked after her when she was ill and started feeling unwell 5 days later 3/
Read 9 tweets
Jul 5
From a prominent figure in paediatrics, statements like this are deeply disappointing. There are thousands of families with #longcovidkids who are struggling. Many of us understand the symptoms kids are suffering as we have taken the time to ask, and we live & breathe it daily 1/
Dr Ladhani claims survey data is ‘unscientific’, how else does one collect data on a large scale about symptoms where little other research currently exists? He is an author on the CLoCK study which based on survey data. Is that therefore unscientific? 2/
There are 12 million kids in the UK, a prevalence of long covid at 8 weeks of 1.8% as stated is still 216,000. Some may have loss of taste/smell, perhaps deemed not serious? But that’s 2/5 senses in a developing brain- awful, I know kids with serious eating issues due to this 3/
Read 10 tweets
Jun 18
In May the @RCPCHtweets published an updated summary of 'key evidence for the effect of #COVID19 in children; rcpch.ac.uk/resources/covi…

This is the entire section on #longcovidkids, note the inverted commas 'Long COVID'. Three publications cited, 2 from 2020 and 1 from 2021 (1)
The cited 2021 ISARIC cohort study shows 25% of children have persistent symptoms post-hospitalisation, with nearly 1:10 experiencing multi-system involvement. No studies in non-hospitalised children are included. Why? Let's look at how studies were selected (2)
It seems in June 2020, the selection process for articles was narrowed, with only research deemed 'relevant' or high quality by consensus being included, 'a clinical academic' was involved. So all articles published on non-hospitalised #LongCOVIDkids since then are excluded (3)
Read 8 tweets
Jun 12
To any new followers, you may see me tweeting about #southasianheritagemonth over the coming weeks. This is a passion project I co-founded with @jasvirsingh in 2020 🧵

TDLR: No one told me when I was growing up that my history was important. I want to change that 1/
In 2017 I took part in a BBC1 Docu called ‘My Family Partition & Me’. I was the first member of my family in 70yrs to go back to Bangladesh (then West Bengal) to the place where my father fled in terror from genocide & retrace my family’s footsteps 2/
Violence surrounded 'Partition' in 1947, the division of the Indian subcontinent by the British, changing millions of lives forever. A 5 minute clip to my Dad’s story here. As you can see if you watch this, it was a pretty emotional journey for me! 3/
bbc.co.uk/news/av/magazi…
Read 19 tweets
May 17
I wanted to share a story of a patient I saw this week. Very fit man aged 52, previous marathon runner, suspected mild #COVID19 March 2020. Extensively investigated by cardiology in 2020 for symptoms of chest pain, dizziness and struggling to exercise 1/
Cardiac MR showed some fibrosis suggestive of previous myocarditis, but all other Ix were normal. By November 2021 he was back to running 15km, but very slow improvement. Dec 2021 had booster followed by COVID re-infection over a couple of weeks (again mild symptoms) 2/
After this he developed similar symptoms to 2020, dizziness on walking up stairs, chest pain (anginal sounding). We did his spirometry and gas transfer - completely normal. On the 1 minute sit-to-stand he desaturated to 92%, HR increased from 49 to 110 and he became quite SOB 3/
Read 13 tweets

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