If you find yourself in the role of a consultant, be kind. The person paging you is asking for help from you, the expert. It's an opportunity to help & educate.
Remember how nervous you might've been the 1st time you called a consult!
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Yes, all those "silly consults" add up to be more work. But remember, you are the expert now, and what is "silly" to you may be truly confounding to the primary team. Something that might seem so simple to you is only that way because of your training, and that's pretty great.
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I still remember the times I got annoyed or angry about a "silly consult." Without fail, I always regretted how I reacted on the phone. It's so much easier to be kind, than to apologize later. You are serving as an ambassador for your specialty to the rest of the hospital!
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Just a few years ago, Sezary Syndrome (SS) was thought to be the leukemic variant of Mycosis Fungoides (MF). We basically thought people had MF, it would keep getting worse, and then it would turn into SS.
But patients often present with either the classic SS exam (red all over, super itchy), or with MF. Some patients would progress from MF--> SS, but it's the minority. So it became clear these are two different processes.
For that reason, we've changed how we think about it... 3/
Let's start by establishing that Wilson Disease is a multisystem process wherein copper deposits in various tissues (liver, brain, eyes) because of improper transport.
A mutation in ATP7B causes this, and the depositional process leads to disease manifestations. 2/
Given the organs Cu2+ deposits in, you see neurologic effects, Kayser Fleischer rings in the eyes, and of course, liver disease.
While here👇, we see the always memorized, rarely seen, Kayser Fleischer rings, let's focus on the liver...
First of all, I have no COIs with any makers of sunscreen! Even so, I'm going to avoid talking about any brands. Instead, we'll focus on the different factors you should consider when picking your favorite.
What is your current preference for sun protection (if any)?
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There's debate in the field right now about whether everyone even needs sunscreen. For this #tweetorial, I'm going to focus on those who've decided they need sun protection.
So 1st rec: The best sunscreen is one you'll actually put on. Doesn't matter if you won't use it!
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The primary lesion isn't enough to make the diagnosis. You're going to need the primary lesion AND time from rash onset to know what you should be expecting to see. 2/
The prodrome that occurs before the rash includes the typical ILI type symptoms of fever, malaise, headache, pharyngitis, and cough. Lymphadenopathy has been billed as a distinguishing feature of MPX from smallpox and Varicella.
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This is an autoimmune blistering disorder that can be triggered by drugs!
Hey #medtwitter, what do you think is one of common culprits for causing this eruption?
2/ You'd be correct if you said vancomycin!
Vanco triggers IgA to attack proteins in the hemidesmosome that holds epidermis to the basement membrane. That means this is a part of the PEMPHIGOID group.
So you get TENSE blisters with a NEGATIVE NIKOLSKY.
3/ For the #dermatology residents who need to memorize this, remember that the antigen that is targeted is the 97 kDa portion of the extracellular domain found in BPAg2.
For everyone, remember this is part of the pemphigoiD (D for deep) group, hence the exam findings.