Yet carbs are essential for maintaining prolonged, high-intensity (top-end) performance.
3/13
Breakfast is a special meal for our liver glycogen (more than muscle glycogen).
This is because liver glycogen is depleted overnight as liberated glucose provides fuel for the brain while we fast.
So, does breakfast matter if we are taking on board carbs during exercise?
4/13
A: Yes! A high-carbohydrate pre-exercise meal can increase capacity for moderate-to-high intensity exercise, even when we are consuming carbohydrates during exercise
5/13
So what about the types of carbohydrate to include in the breakfast?
Some of the main types of carbs can be seen below. Most cereals (e.g. pasta and rice) will be polysaccharides (chains of glucose molecules).
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Fructose though, is a bit special...
6/13
After exercise, ingesting fructose-containing carbs (e.g. sucrose) can accelerate (by up to 2-fold!) the replenishment of liver glycogen stores
7/13
Another potential benefit of ingesting fructose alongside glucose-based carbohydrates is providing a separate route for carbohydrate absorption in the gut (i.e. more rapid total CHO absorption)
10/13
So based on this background, it was hypothesised that adding fructose to a carbohydrate-rich breakfast might increase exercise capacity.
To test this, cyclists were provided with rice-based breakfasts with added glucose or fructose (to match for total carbohydrate) 11/13
Interestingly, exercise capacity was increased by ~5% with the rice+fructose versus the rice+glucose
The idea that males display more between-individual variance than females has been considered for >150 years
In humans, this might be (partly) due to averaging of two parental copies in the homogametic sex but not in the heterogametic sex.
Since (premenopausal) women display greater day-to-day variance in sex hormones, it is reasonable to assume that women may display greater day-to-day variance in metabolic outcomes affected by sex hormones.
For context, the relationship between LDL-cholesterol concentration and coronary heart disease risk appears linear across the entire physiological range
If mice π are calorie restricted π½οΈ for a prolonged period of time (provided 30% fewer calories than they would choose to eat normally at baseline), what will happen to DNL?
2/8
The Q is a bit vague to have a clear A, as it depends if we are talking about DNL in liver, adipose tissue, or the whole body.
Before we delve into those areas, its worth noting that mice do lose weight when restricting calories by 30%