Short🧵Why I think #Covid can cause existential consequences for Human Race ?? For any species to continue it has to procreate,that depends on fertility of both men & women.We started getting edgy couple of months ago.Here's the original ctd
Ctd3) We know that the number of ova in a woman is fixed at birth.The body doesn't produce more ova.Only a fixed number mature rest die off , maturation needs hormones & lots of other factors. If either hormones or reservoir is reduced #risk ctd) my.clevelandclinic.org/health/article….
Ctd4) with kids being repeatedly infected we are exposing the female kids to both damage to the cells which produce the hormones & also to reservoir cells- we may end up with a pandemic of #infertility caused by #Covid in the next 10 yrs ctd)
Ctd5 )Patients with higher levels of IgG against SARS-CoV-2 had lower numbers of retrieved oocytes. #Covid adversely affects the follicular microenvironment, thus dysregulating ovarian function. Ctd)
doi: 10.1016/j.bbadis.2021.166295.
Ctd6 ) #Covid significantly associated with serum anti-Müllerian hormone [AMH], suggesting an independent risk factor for ovarian function, which accounted for 3.2% of the ⬇️ in AMH, 14.3% of the ⬆️ in Testosterone, and 20.7% of ⬆️in prolactin ctd)
doi: 10.3389/fmed.2021.635255.
Ctd7) By exposing kids especially females & that too repeatedly we are causing them harm in the short run and probably in the long run causing #existential crisis .I hope to be proved wrong .🤞🏾🤞🏾
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Small 🧵on how repeated infections are causing mayhem - I treat kids who have #clubfeet , the kids have to be plastered every week and finally a small incision has to be made I prefer sedation ( sleep) because it allows me to do the small incision without the kid fighting me ctd)
2/n The reason why I called my friend the Pediatrician in the first place in the tweet below was that kids have to have a clear 6 weeks "No Chest Infection "history ,for us to take them to Operation Theater & do the surgery & I wasnt finding that zone ctd
3/n I have had kids get ok enough at around 6 weeks for me to plan a surgery , repeat the relevant investigation ONLY to find the kid getting sick with upper respiratory tract infections before the proposes date. It is difficult to get kids into Operation theater ctd)
Short 🧵 My pediatrician batchmate always called me a little over concerned about #Covid effects in kids .Normally he picks up my phone in 1st ring BUT today he didn't. He called a couple of hours later apologizing for the inability - He said & I quote "I really dont know - Ctd)
Ctd1) " what is happening anymore - I am getting kids having infection & fever every 15- 20 days. Havent seen this ever in my life. They don't respond to antibiotics.All basic investigations okay. Looks like a viral infection.Kids get okay BUT the parents are very tensed ctd)
Ctd) " Constant / repeated fever means kids can't to school .Mothers have to miss work. All in school going kids. I have started telling parents I don't know what is happening anymore. I think you were right in saying that Covid is causing something to the immunity of kids. Ctd
First doctor falls to #Ebola Dr. Mohammed Ali, a Tanzanian national, 37-year-old Male,pursuing further studies in te country .He tested+ve on September 26 & died while receiving treatment at a hospital in Fort Portal, a town about 300 kilometres west of the capital Kampala.
Dr. Ali may be the 2nd health worker to have succumbed to Ebola. The first could be a midwife from St. Florence Clinic, a probable case because she died before testing,at the moment 5 more health workers are battling the disease including an anesthesiologist & a medical student.
The outbreak has also infected intern doctors and senior house officer (all trainees) who were stationed at the centre of the outbreak at Mubende Regional Referral Hospital, according to Uganda Medical Association (UMA).One more doctor is in precarious condition. Ctd)
Small #monkeypox thread - detected in 10 of the 11 sewer systems that SCAN (Stanford’s Sewer Coronavirus Alert Network) tests, including Sacramento, Palo Alto & several other cities in California’s Bay Area. So we are going to see big outbreak in 2-3 weeks apparently.ctd)
2/n Bavarian Nordic can produce 30 million doses/ year and so far hasn’t turned down any orders from governments, considering night shifts & other tweaks would bring production above 30 million but in 3-4 weeks they will reach the tipping point - with the virus ripping ctd)
3/n this will throw couple of scenarios- 1) they would be forced to transfer tech which they dont want & is not east to do 2) countries may be forced to use old tech with higher incidence of myocarditis risk which will be difficult to get people to agree to use ctd)
1/n A small thread on what I found problematic with Dr Jha's & what I liked - first ❤ " I always lean on people getting more rest - so people who were pushing for @Potus to work dont have Dr Jha's support -Potus isn't Superman ,he should rest & that should be the messaging ctd)
2/n I have trouble in accepting that its going to be simple- already seeing pet animals being infected - a reservoir is being fast built , we wasted crucial time in thinking it will remain within the MSM circuit , didn't stop pride marches-didnt trace well - missing chance ctd)
3/n There is a big problem that there is lack of data , data has to be seen real time - There isn't enough vaccines to do ring vaccination- there should be proper state ,federal coordination - this passing the buck doesn't help ctd)
Why are we going to see an avalanche of infertility,problems in conceiving in the next couple of years?? Well this is a 500 plus young men less than 29 yrs cohort in swiss army who were evaluated & higher incidence of lipid issues,pre -diabetes found ctd) doi.org/10.1101/2022.0…
Ctd2 we already know from past studies that 26% of young take more than 2 weeks to be " Normal", interestingly this one study used a larger number of parameters to prod a little more than others ctd)
Ctd3)They used diffusion studies in addition to standard spirometry, PRO-BNP & Troponin to evaluate cardiac function,test on treadmill to stress the system,sniffing tests , eye tests, taste tests, psychological tests, sperm count & testosterone levels in post #Covid males ctd)