When is the best time to take BP-lowering medicines: morning or night?
High BP (#hypertension) is a common risk factor for causing #stroke, #heartattack, #heart failure and #death. Keeping BP within normal limits is one of best ways to prevent these complications.
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High BP (#hypertension) is a common risk factor for causing #stroke, #heartattack, #heart failure and #death. Keeping BP within normal limits is one of best ways to prevent these complications.
#MedTwitter
In people without hypertension (HTN), BP is usually lower during nights (#sleep), however, in people with HTN and people aged 55 or more, BP can actually rise during sleep (reverse dipping). Studies have shown a higher incidence of heart attacks and strokes in early mornings.
In a large clinical research done in Spain in about 20,000 people, who were followed up for >6 years, people who take their BP medicines at night time had better 24-hour BP control, including at nights, as compared to those who take BP medicines in mornings.
Those who switched their blood pressure medications from morning to night experienced:
A 44% drop in heart attack risk
A 40% reduction in the risk for coronary revascularization (need of bypass surgery or stenting)
A 42% lower risk for heart failure
A 49% reduction in stroke risk
A 44% drop in heart attack risk
A 40% reduction in the risk for coronary revascularization (need of bypass surgery or stenting)
A 42% lower risk for heart failure
A 49% reduction in stroke risk
Conclusion: Switching BP medicines from morning to night may be beneficial in preventing death due to heart attack and stroke. Talk to your doctor before taking the final decision. (Ref: European Heart Journal, December 2020)
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