@drPaulElbers@ESICM@patrickthoral Help recommend Readiness scale. Shockingly most of the research remains in model development phase. see image
WHAT are the barriers for getting to bedside 1. you cannot develop model without data. - data availability problem 2. compliance with legislation and reporting 3. integration into work flow and EHR 4. local stakeholder engagement 5. model generalisability and data drift
6. Unpredictable interaction 7. all of this results in "prohibitive cost"
very difficult for individual hospitals to do. require national or private sector in his view.
Now discussing Dutch Data Warehouse combining Meta Vision , HiX and EPIC systems into 1 warehouse
Framework for DECIDE-AI consensus. The goal is to minimise paperwork and help with compliance, GDPR, Medical Device Regulation, Artificial Intelligence Act(coming). MDR is needed right at the very end.
Amount of docs required for the pipeline
Pipeline
To get to bedside model - you need a lot more stakeholders - EHR , IT, Software engineers, Network engineers, Data Scientists, Ethical Boards.
Liu(2020) article : future of AI in critica care is augmented, not artificial.
Impressive piece of work overall in @amsterdamumc Incredible timeline and Gantt chart
@amsterdamumc FINAL TAKEHOME : cannot leave this for multi-national industry to solve this. Need ownership by patients and doctors. Hence perhaps we need "department of clinical artificial intelligence" in each hospital.
Insightful !!
Do you think we are there yet ^^ ?
@amsterdamumc Question : difficulty in regulator, some regulators require submission even before model evaluation 😳 .
Challenge even within EU which is supposed to be more "uniform"
Q: Difficulties in collecting data in the context of GDPR.
@amsterdamumc In his view, GDPR is strict but need to demonstrate that your data is anonymous. Aim for less than 1 in 20 and aim for GDPR anonymity framework. No body has been ever re-identified so far.
Mariangela PELLEGRINI
Uppsala- Sweden
"Do we Need a biological definition of ARDS"
- Berlin definition has NO Diffuse alveolar damage .
- the Berlin defn does not capture well
Frohlich - different definitions specificity of 0.63, 0.42, 0.31 even! #ventilation#ards#LIVES2022
ARDS - new definition or phenotypes by @GicoBellani refreshing with Kigali definition of ARDS - useful not just low resource but during pandemic in supposedly high income settings and only draw back is no PEEp requirement #ards#ventilation#LIVES2022@ESICM
@GicoBellani@ESICM Resolved versus confirmed ARDS
- prospectively applying Berlin definition did work but if ya wait 24 hrs and re-measure P/F ratio, you end up stratifying much better.
- Better separation of groups
NEXT Speaker : VA ecmo for which patients?
Alain COMBES
Severe cardiogenic shock has different phenotypes 1. medical cardiogenic shock(AMI, end stage dilated CM, myocarditis, septic shock) 2. Post cardiotomy refractory CS (post CABG) #LIVES2022 @ESICM#ecmo#resuscitation#ALS
@ESICM 2022 what do the guidelines say
- ESC recommends short term MCS should be considred in cardiogenic shock.
IABP may be considered but not routinely recommended in post MI #LIVES2022