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Dec 8, 2022 19 tweets 13 min read Read on X
1\
WEEK 47 Corona #oversterfte

CBS: 383† (+13% pw)
AB:   745† (+8% pw)
Pandemie: >94.000†  RIP

• Exponentiële groei
• Ontwikkeling varianten wereld/NL
• Geen reactie Rutte/Kuipers/RIVM
• Risico: blijvend (zeer) hoog

Fig @falsel_net
2\
▶️ Riool-RNA-meting stijgt naar 951 (5/12), met een verdubbeltijd van 28 dagen. De dagelijkse stijgingspercentages zijn ca 2,5%...,
⬇️
Fig ht @covid_nl
3\
... waarmee de exponentiële R-riool rond ca 1,1 is, het laatst bekende niveau van 30/11.

Fig  ht @covid_nl
4\
Zie ook lokale R-riool-(groei)cijfers van 5/12.
⬇️
Fig ht @covid_nl
5\
🏥 IC-opnames en ziekenhuisopnames zullen met een vertraging  van 1-2 weken volgen.

Iets minder dan 12% van zh-opnames sterft; terwijl het aantal (herstelde) patiënten sterk is toegenomen.
6\
▶️ Weliswaar heeft de huidige boostercampagne een mitigerend effect op mortaliteit/pathogeniciteit (ernst van het virus), maar niet zo zeer op transmissie (gevaarlijkheid).
7\
De virusprevalentie is hoog(~4,5%) en bij een relatief lage IFR* van Omikron, sterven meer jongere mensen (0-50) dan verwacht.

Rekening is te houden met (snelle) afname van de werkzaamheid van de  vaccins en/of meer frequente herinfecties.
Fig @falsel_net
8\
'Mild' Omikron een stille moordenaar en long-covid verwekker. Het verspreidt snel door kinderdagverblijven/scholen zonder preventie, en besmet kinderen asymptomatisch en met regelmaat opnieuw.
9\
Naar schatting zijn er 39 mio #SARS-2 infecties in Nederland geweest.

Het aantal herinfecties bij kinderen is hoog (nb superspreading). Het daalt weliswaar vanaf 20-25 jaar langzaam, maar stijgt na de 80-85 jaar weer (zie fig).
10\
De trend stemt niet optimistisch (fig ht @falsel_net).

Bij stijgende prevalentie van corona(-varianten), en door verhoogde bevattelijkheid, ook voor mn Influenza- en RS-virussen, zal op kortere termijn en bij ongewijzigd beleid, de zorgdruk, ziektelast en sterfte stijgen.
11a\
Sterfte *mét-pandemie cq corona* is ca 20% hoger dan het historisch gemiddelde *vóór-pandemie cq corona*; een cijfer zoals in vrijwel de hele westerse wereld.
Fig @falsel_net en HMD
11b\
Kenmerkend in NL: de vrijwel afwezigheid van Influenza- en RS-virussen, bijv. in een periode sinds week 41.
ht @falsel_net
12\
▶️ Stijgende prevalentie varianten; vaak immuunontwijkend.

Update convergerende varianten:
• XBB, XBB.1, CH.1.1, BA.4.6.3 en BQ.1.1.10 zijn momenteel meest immuun-ontwijkend
• BQ.1* met NTD-mutaties, maakt de variant zeer immuun-ontwijkend.
13\
In NL blijft het aandeel BA.4/5 sterk dalen. In week 47 is het aandeel 27% .

Aandeel BQ.1* stijgt sterk; naar 58%. NB de variant is zeer immuunontwijkend.
XBB (ook sterk immuunontwijkend) staat op 5%. CH.1.1 beginnend.

Fig ht @ARGOSamsterdam
14\
Op wereldschaal valt het grote aandeel van respectievelijk BQ.1.1 en BQ.1 op.
⬇️
public.tableau.com/app/profile/ra…
15\
▶️ We verwachten afwachtend en ongewijzigd kabinetsbeleid gericht op groepsimmuniteit.

Totaal mislukt beleid.
Bron @AlleBurgers Lancet @Commissioncovid
⬇️
alleburgers.nl/media/rutte-ku…
16\
NL laat de pandemie voortslepen. Samengevat:
"Coping, postponing and hoping"

Alle risico's van oversterfte, long Covid, economische sociaal-economische schade etc krijgen alle ruimte.
17\
▶️ Samenvattend
NL-Pandemiebeleid:
• Geen werkzame indamstrategie, en inadequate uitvoering, en monitoring (via oversterfte)
• Niet bestand tegen opkomende risico's (ransmissie, varianten)
• Maatschappij-ontwrichtende effect (long) Covid

RISICO:
BLIJVEND HOOG/ZEER HOOG

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More from @AlleBurgers

May 21
1\🧵
🚨 BREAKING. FDA announces the end of "Repeat-COVID-Boosters In-Perpetuity Strategy."

FDA says for most Americans we do not have evidence supporting an annual booster strategy. COVID is not flu.
2\🧵
The full press event, and briefing documents for Thursday's meeting of FDA's outside advisors:

.ht @emilyakopp
3\🧵
US had adopted a one-size-fits-all regulatory framework and has granted broad marketing authorization to all Americans over the age of 6 months.

Other high-income nations confine vaccine recommendations to older adults (>65 years), or those at high risk for severe Covid-19. Image
Read 18 tweets
May 13
1\🧵
"Corrupt Medical Journals and Mostly Junk Research"

Producing devastating impact of origin of COVID, Fauci's cover up, massive failure in response.

Citizens need creative destruction:
REFORM public health NOW. Work on transparancy, truth, and trust!
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2\🧵
Source:

"Even top journals are industry mouthpieces, churning out junk to push drugs. Trusting them is like trusting cigarette ads from the '50s."

.ht @DrWojakMD
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3\🧵
Today, US administration (DoJ) investigates @NatureMedicine COVID publication "Proximal Origin" by Andersen et al.

DOJ's officials believe the paper was a quid pro quo for a Fauci grant.

We think it is an illustration of one of the pandemic scenarios.
Read 37 tweets
May 5
1\🧵
🚨 BREAKING Today, President Trump will sign an executive to ban all federal funding of risky gain-of-function research without proper oversight of the experiments...

...US intel agencies said this research most likely produced origin of COVID resulting from a lab accident.
2\🧵
The order stops funding from “any present and all future” gain-of-function research...

...as well as deputize the National Institutes of Health (NIH) and other agencies to identify biological research harmful to public health or threatening to national security.
3\🧵
“These measures will drastically reduce the potential for lab-related incidents involving gain-of-function research...

...like that conducted on bat coronaviruses in China by the EcoHealth Alliance and Wuhan Institute of Virology.”
Read 9 tweets
May 2
1\🧵
"Every vaccine innovation must be grounded in gold-standard science and transparency, and subjected to highest standards of safety and efficacy."

US Dep. Health (HHS) and NIH announce development of next-generation, universal vaccine platform, Generation Gold Standard. Image
2\🧵
Shift toward transparency, effectiveness, and comprehensive preparedness with universal influenza and coronavirus vaxx.

Aim: broad-spectrum protection against multiple strains of pandemic-prone H5N1 avian influenza, and coronaviruses, incl SARS-CoV-2, SARS-CoV-1, and MERS.
3\🧵
Clinical trials for universal influenza vaccines are scheduled to begin in 2026, with FDA-approval targeted for 2029.

The intranasal BPL-1357 flu vaccine, currently in advanced trials, is also on track for FDA review by 2029.
Read 5 tweets
May 2
1\🧵
How deep are Marion Koopmans' lies, while US accuses PARTNER Daszak of pandemic origin at Wuhan lab with MAD SCIENCE financed by Fauci ?

"[WIV] conducted some mad science experiments, *unfortunately partly funded by NIH*. That experiment went astray and leaked..." Image
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2\🧵
In order to track and trace anomalies [EcoHealth WIV], US NIH will establish a new award structure that prohibits foreign subawards.

.ht @R_H_Ebright
Image
3\🧵
Citizens and (their) politicians have a right to know, leading to transparancy, truth and trust; no secrecies!

Read 4 tweets
May 1
1\🧵
INMEDIATE CLOSURE NIAID BSL-4 lab at Fort Detrick.

"Integrated Research Facility located at the US Army base in Frederick, Maryland, told to stop all experimental work by April 29...The facility is part of [Fauci's, Taubenberger] NIAID."
2\🧵
NIAID conducts research on treatment and prevention of infectious diseases deemed “high consequence”, with significant risks to public health.

The facility is one of the few federal facilities charged with studying Ebola.
3\🧵
"NIH has implemented a research pause, referred to as a safety stand-down.

This decision follows identification and documentation of personnel issues involving contract staff that compromised the facility’s safety culture, prompting the research pause."
Read 7 tweets

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