Jorge Álvarez Troncoso Profile picture
Feb 11, 2023 10 tweets 11 min read Read on X
#VEXAS syndrome
Dra. Eugenia Enriquez Merayo
#25TenTopics #TenTopics 🧵🩻🧪💉💊🏥
#VEXAS syndrome
Expansión de su definición
#25TenTopics #TenTopics 🧵🩻🧪💉💊🏥
#VEXAS syndrome: prevalence
- 1:13591 total population
- 1:4269 in ♂️>50y
#25TenTopics #TenTopics 🧵🩻🧪💉💊🏥
#VEXAS syndrome: symptoms
- Ferrada cohort
- Georgin-Lavialle cohort
#25TenTopics #TenTopics 🧵🩻🧪💉💊🏥
#VEXAS syndrome: thrombosis
- 40% of patients 🚨
#25TenTopics #TenTopics 🧵🩻🧪💉💊🏥
#VEXAS syndrome: algorithm & biomarkers
#25TenTopics #TenTopics 🧵🩻🧪💉💊🏥
#VEXAS syndrome: clusters
#25TenTopics #TenTopics 🧵🩻🧪💉💊🏥
#VEXAS syndrome: treatment
- AZA/MTX?
- tocilizumab/anakinra
- ruxolitinib (best of JAKi) -- higher dose?
- azacitidine
- transplant
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#VEXAS syndrome: transplant
#25TenTopics #TenTopics 🧵🩻🧪💉💊🏥
#VEXAS syndrome: summary
#25TenTopics #TenTopics 🧵🩻🧪💉💊🏥

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