Mitochondria & Mental Illness. What are the basics of why those are so intimately intertwined? 🧵(1/8)
Mitochondria play a crucial role in various bodily functions, including neurotransmitter release, hormone regulation, inflammation control, and cell development. (2/8)
Deficiency or dysfunction in mitochondria can result in cell malfunction, leading to imbalances in neurotransmitter release, hormone levels, and inflammation control. (3/8)
These imbalances can result in overactive or underactive regions in the brain, contributing to the symptoms of mental illness. (4/8)
Scientific advancements over the last 25 years have shed light on the important role that mitochondria play in mental health. (5/8)
The relationship between mitochondria and mental illness highlights the importance of addressing mitochondrial health in addressing and treating mental health conditions. (6/8) #mitochondria#mentalhealth#neuroscience#neurotwitter
If you want to learn more and want to see references to the peer-reviewed literature, I recommend the book Brain Energy by @ChrisPalmerMD, and you can find it anywhere (7/8) penguinrandomhouse.com/books/710914/b…
Ketogenic diets have neurotransmitter-balancing effects. Let's do a short thread on one of my fav NTs called GABA. 🧵
GABA makes you chill out. It relaxes your mind and reduces your sense of being overwhelmed. It reduces anxiety. It helps you digest your food and actually improves gut motility and, thus, gut health because it's used to keep your parasympathetic nervous system humming along.
It also helps reduce a little something called #neuroinflammation, which, if you have any kind of mood disorder, might very likely be an issue for you.
Some of you with cognitive symptoms #brainfog have genetic differences that mean you cannot produce enough choline. 🧵(1/10)
If you have these genetics, to get enough choline, you would have to eat 8 eggs a day. And while some of you really love eggs and are into that, that won't work for many of us. So why is having these genetic differences a problem? (2/10)
Because choline is a precursor to acetylcholine. This is a major neurotransmitter that helps run the "rest and digest" part of your nervous system. It's used for sleep. (3/10)
Maybe we could just make sure everyone gets their Vitamin D level checked every time they get sent for labs? (1/6)
Or better yet, maybe you, as the patient, can self-advocate and insist it is done. Every three months is a good pace, as it can fluctuate mightily throughout a calendar year! But don't get hung up on a schedule of testing. Just get it done! (2/6)
So you go to your doc to discuss the use of a ketogenic diet to treat your mental illness and or neurological disorder, and they are like, "Oh no! the evidence is not good enough to do that!" or some such... what do you do? 🧵(1/9)
Well, if you like your doctor and you don't want to go get a second opinion from some other epic low-carb informed doc, you're going to need to educate them.
You tell them this 👇(2/9)
"Why wouldn't I want to use a ketogenic diet as an intervention? There are many advantages, but from a scientific standpoint, we have over 100 years of evidence supporting its safety and efficacy in epilepsy. (3/9)
So you go to your doc to talk about using a ketogenic diet to treat your mental illness and faltering cognitive function, and they are all like, "Noooo you need fiber and whole grains!" What do you do? 🧵(1/9)
Mostly you get a low-carb doc that knows better. But if you like your doc and you want to educate them, you can do that! Here's what you tell them! (2/9)
Ketogenic diets do not have to be low fiber because above-ground veggies and nuts that you eat on a keto diet have oodles of fiber. If you have digestive issues, there is a whole research body saying you should prob stay away from fiber, but that's a diff thread. (3/9)
So you visit your doc about using a ketogenic diet to treat your mental illness or cognitive dysfunction, and they say absolutely not! Your brain needs glucose! What do you do? 🧵(1/8)
Many college-educated dietitians still believe that the body needs 130 grams of carbohydrates per day. So why would your poor doctor, with their super limited nutrition education, know any better? (2/8)