Discover and read the best of Twitter Threads about #brainenergy

Most recents (13)

In this thread, we will have fun talking about how a ketogenic diet makes for a healthy brain. And sharing just a small portion of the research that proves I am not making this up! Are you ready? 🧠🧵(1/14)
The ketogenic diet (KD) has been linked to significant neuroprotective effects, with Beta-hydroxybutyrate acid (BHBA) playing a key role in preventing neurodegenerative disorders. I kid you not. Ketogenic diets are no joke when it comes to having a kick-ass brain! (2/14)
Microglial cells play a crucial role in neurodegenerative disorders, but BHBA from the ketogenic diet can help. It promotes an anti-inflammatory microglial phenotype, reduces migration, and modulates cytokine levels. The implications for neuroprotection are off the charts! (3/14)
Read 14 tweets
Central to Alzheimer's pathology is a phenomenon known as brain hypometabolism. Let me explain better what that term means. 🧵 (1/25) #alzheimers #AD #neurotwitter
Brain hypometabolism refers to a state of reduced metabolic activity in the brain, characterized by a decreased uptake and utilization of glucose - the primary #energy source for brain cells. (2/25)
This disastrous metabolic slowdown is not just a mere lack of energy, although that would be devastating enough. It triggers a cascade of effects that impair neuronal function and disrupts communication between #brain cells. (3/25)
Read 25 tweets
What causes auditory hallucinations, persecutory delusions, thought broadcasting, and insomnia?

In this case, it was vitamin B12 deficiency.

How often do we just diagnose it as schizophrenia and call it a day?

Rates of B12 deficiency were estimated to be 47% in this north Indian population.

How many people diagnosed with schizophrenia in this population actually just had B12 deficiency?

If there was even one, that person's life has likely been ruined.…
ANYONE who has these symptoms has a REAL medical problem.

It's a metabolic problem in their brain that needs to be identified and treated.

It's not rocket science... it's neuroscience! (love this quote from @MasinoSusan)
Read 3 tweets
We are discovering exciting things about how therapeutic nutritional ketosis could benefit those living with serious mental illnesses. It's time for a short thread about two main ways this could be happening. 🧵 (1/13)
First is the direct effect of ketones. Scientific studies have shown that people with serious mental illnesses often have trouble using glucose efficiently for fuel. Ketones supply fuel that doesn't depend on insulin or the cell's ability to metabolize glucose. (2/13)
By providing the brain with this alternative fuel source, ketones can help enhance energy production and improve cognitive function in people with serious mental illnesses. (3/13) #lifechanging
Read 13 tweets
Mitochondria are essential to our overall health and well-being. In addition to producing energy, they regulate many critical processes in the body. (1/11) #mitochondria #energy #health
Mitochondria play a key role in the production and regulation of neurotransmitters. They also help produce key hormones like cortisol, estrogen, and testosterone. (2/11) #mitochondria #hormones #neurotransmitters #neurotwitter
Mitochondria are involved in epigenetics, which is the expression of #genes from the nucleus. They send signals to the nucleus that turn genes on or off. (3/11) #epigenetics #genes #mitochondria
Read 11 tweets
A lot of you understand that a ketogenic diet is a powerful mitochondrial intervention, but you might be a little unclear on how micronutrient availability can enhance mitochondrial function. 🧵(1/15)
Some of you have or had a bit of increased energy when you started your ketogenic diet, but it wasn't sustained very well. (2/15)
There can be a lot of reasons for that but one common and understandable one, given the shape people are often in when they begin the diet, is micronutrient status. (3/15)
Read 14 tweets
Mitochondria & Mental Illness. What are the basics of why those are so intimately intertwined? 🧵(1/8)
Mitochondria play a crucial role in various bodily functions, including neurotransmitter release, hormone regulation, inflammation control, and cell development. (2/8)
Deficiency or dysfunction in mitochondria can result in cell malfunction, leading to imbalances in neurotransmitter release, hormone levels, and inflammation control. (3/8)
Read 8 tweets
So you go to your doc to discuss the use of a ketogenic diet to treat your mental illness and or neurological disorder, and they are like, "Oh no! the evidence is not good enough to do that!" or some such... what do you do? 🧵(1/9)
Well, if you like your doctor and you don't want to go get a second opinion from some other epic low-carb informed doc, you're going to need to educate them.
You tell them this 👇(2/9)
"Why wouldn't I want to use a ketogenic diet as an intervention? There are many advantages, but from a scientific standpoint, we have over 100 years of evidence supporting its safety and efficacy in epilepsy. (3/9)
Read 9 tweets
Twitter Thread Alert! 🧵It's time for a mini-review of the literature on the use of #ketogenic diets and #Autism. Now some of you identify as neurodivergent and are not interested in modifying these differences. #neurotwitter 1/29
You may also not want to participate in a discussion that sees these differences as pathology. If that is the case, this is not the thread for you. I am not interested in hosting that philosophical discussion in this thread. 2/29 #boundaries
This thread is for people who are experiencing distress around what they experience as symptoms, and they deserve to know all the ways they can feel better. And I am going to tell them. So with that caveat, let's begin.👇3/29
Read 29 tweets
When providers talk to people about changing their health behaviors— eating less or exercising more—they often get similar answers: “It’s too hard,” or, “I don’t have enough energy.” 🧵
These answers are almost always met with strong disapproval. They are viewed as excuses for laziness, or signs of not taking the issue seriously enough, or of a lack of discipline.
But is it possible that instead of being excuses, answers like “It’s too hard” and “I don’t have enough energy” are actually clues giving us important information?
Read 6 tweets
Defining what "dysfunction" means is difficult and has been a challenge to scientists; it can mean very different things in different research studies. 🧵
The same can be said for cars. If a car is “dysfunctional,” what does that mean? It could mean that the engine sputters when traveling down the highway.
It could mean that a tire is flat, and the car can’t move along the road as easily. It could mean that the lights and the turn signals aren’t working.
Read 8 tweets
Let’s talk about #mitochondria and #mentalhealth. Specifically, mitochondrial dysfunction…

Mitochondrial dysfunction is the term most frequently used to describe impairment in mitochondrial function. 🧵
The diseases and illnesses that have been associated with mitochondrial dysfunction are widespread, and the list includes almost all of the psychiatric disorders.
It also includes the metabolic and neurological disorders such as obesity, diabetes, cardiovascular disease, Alzheimer’s disease, epilepsy, many cancers and Parkinson’s disease, and more…
Read 9 tweets
Ready for a quick #science lesson? 🧵

In your body, energy needs to be produced in the right amount, in the right place, at the right time, and it goes through an unimaginably fast recycling process that involves #mitochondria.
The #mitochondria that aren’t moving appear to stay in places where things are always happening—either near factories where proteins are made (ribosomes) or synapses where there is a lot of activity, which is a very important fact relevant to how the #brain functions.
Researchers looking at #braincells under #microscopes have known for decades how to identify where the synapses are—they look for the mitochondria.
Read 7 tweets

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