Thread by @angryhacademic

Got some blood test results back from a #SIRENstudy sub-study @vibrant_uk

They're trying to understand if there's immunological factors that prevent some people getting infected (among other things). 🧵

As a "never infected" participant, I got to partake. though my infection status is due to FFP3 & living a fairly isolated disabled life rather than my immune system being super awesome

tho clearly my immune system is a bit wonky

https://twitter.com/angryhacademic/status/1602746444309745667

#postvac #vaccineinjuries

anyway, all normal:
IgG 8.2 g/L (ref: 6-16)
IgA 2.5 g/L (0.8-4)
IgM 1.2 g/L (0.5-2)

suggests no signs of autoimmunity, in line with all the negative autoimmune tests i've had, except the questionable CellTrend ones

https://twitter.com/angryhacademic/status/1522305675556278274

Serum free light chains:
Kappa 14.6 mg/L (ref: 3.30-19.40)
Lambda 10.2 mg/L (5.71-26.30)
Kappa:Lambda 1.431 (0.26-1.65)

nothing interesting here. free light chain abnormalities can indicate amyloidosis. symptoms that can include weakness, fatigue, numbness/tingling in arms/legs

i fit the symptoms but no sign this is part of my pathology

Protein electrophoresis: normal

This can indicate inflammatory diseases.

A limitation of these results is that im on immunosuppressive drugs: fludrocortisone, aspirin, ketotifen

still positive for spike antibodies. based on the Abbott kit we were using locally, im nearing the minimum the test can detect, so i doubt this is a high positive

still negative for nucleocapsid antibodies. shocked face.

Hep B antibodies 988 miu (> 100 = immune)

This is a relief. I was advised wrong in my PhD and only got 2 of the 3 shots and no Ab test at the time. I was then advised to get my 3rd whilst working in the NHS. i refused because of my COVID vax reaction, so glad im well protected

Varicella Zoster antibodies: positive

Measles antibodies: positive

Relieved to see measles is +ve as my med records indicate i only had 2 MMR jabs as a kid, dunno why. again i refused the 3rd when offered working in NHS due to my covid vax reaction

Lymphocyte subsets: normal

im not sure these data are useful to the study. as above im very COVID cautious, wearing face fitted FFP3s at work, out and about, and if anyone comes in the flat (they also wear FFP3 and the windows get opened). plus the meds im on might skew things. but i found it interesting!