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Jun 5 โ€ข 14 tweets โ€ข 7 min read Twitter logo Read on Twitter
1) #LongCovid: Research progresses, ๐ฉ๐ฌ๐ฒ๐œ๐ก๐จ๐ฌ๐จ๐ฆ๐š๐ญ๐ข๐œ ๐ž๐ฑ๐ฉ๐ฅ๐š๐ง๐š๐ญ๐ข๐จ๐ง๐ฌ ๐ฅ๐จ๐ฌ๐ž ๐ฌ๐ข๐ ๐ง๐ข๐Ÿ๐ข๐œ๐š๐ง๐œ๐ž

"....๐‹๐จ๐ง๐  ๐‚๐จ๐ฏ๐ข๐ ๐ข๐ฌ ๐š ๐ซ๐ž๐š๐ฅ๐ข๐ญ๐ฒ, ๐ข๐ญ'๐ฌ ๐ญ๐ข๐ฆ๐ž ๐ญ๐จ ๐š๐๐ฆ๐ข๐ญ ๐ข๐ญ"

slate.fr/story/247628/cโ€ฆ
2) In April-May 2020, French Twitter users suffering from lingering Covid-19 symptoms started the hashtag #aprรจsJ20. This quickly spread worldwide, with people sharing their experiences with persistent symptoms.
3) Italian researcher @elisaperego78 was the first to use the term "Long Covid". This virtual mobilization led to media and doctors starting to take the issue seriously, while others dismissed it.
4) In times of vaccine shortage and lack of masks, the idea of a mild disease that could become almost chronic and seriously disabling was alarming.
5) The non-specificity of symptoms and the mental and cognitive aspects of Long Covid led some doctors to interpret it as a psychosomatic or functional disorder.
6) Not long ago, diseases such as gastric-duodenal ulcers were viewed as "anxiety diseases" and Parkinson's as a mental illness. Long Covid's prevalence is slightly higher in women, leading to sexist and paternalistic prejudices,
7) claiming it's a disease of "women who focus too much on themselves". This attitude is problematic as it discredits patients' suffering and denies that they may have serious health problems.
8) Denying mental health issues hampers the search for effective solutions. It leads to rejection by doctors and society, isolates those affected, and makes them vulnerable to charlatans, who promise quick healing through useless or dangerous methods.
9) This attitude risks breeding mistrust towards health professionals and promotes misinformation.
This is particularly problematic as #LongCovid can be a very disabling disease and those affected can already be isolated due to their symptoms.
10) Nowadays, this dismissive attitude is untenable as research on Long Covid is making progress,

even though the exact causes and biological mechanisms are still unclear. There are several solid hypotheses being investigated to explain the organic substrates of the disease.
11) These include a deregulated immune response, persistence of SARS-CoV-2 in mucous membranes and organs, a disruption in monocyte function, and excessive production of the pathogenic protein #HERV-W-ENV.
12) Each of these hypotheses could help explain the symptoms of #LongCovid and develop new treatment approaches.

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More from @DinoWithLC

Jun 5
1) #LongCovid: Die Forschung macht Fortschritte, das "๐š๐ฅ๐ฅ๐ž๐ฌ ๐๐ฌ๐ฒ๐œ๐ก๐จ๐ฌ๐จ๐ฆ๐š๐ญ๐ข๐ฌ๐œ๐ก๐ž" ๐ฏ๐ž๐ซ๐ฅ๐ข๐ž๐ซ๐ญ ๐š๐ง ๐๐ž๐๐ž๐ฎ๐ญ๐ฎ๐ง๐ 

"....๐‹๐จ๐ง๐ ๐‚๐จ๐ฏ๐ข๐ ๐ข๐ฌ๐ญ ๐ž๐ข๐ง๐ž ๐‘๐ž๐š๐ฅ๐ข๐ญ๐šฬˆ๐ญ, ๐ž๐ฌ ๐ข๐ฌ๐ญ ๐™๐ž๐ข๐ญ, ๐๐š๐ฌ ๐ณ๐ฎ๐ณ๐ฎ๐ ๐ž๐›๐ž๐ง"

slate.fr/story/247628/cโ€ฆ Image
2) Im April-Mai 2020 starteten franzรถsische Twitter-Nutzer, die unter anhaltenden Covid-19-Symptomen litten, den Hashtag #aprรจsJ20. Dies verbreitete sich schnell weltweit, wobei Menschen ihre Erfahrungen mit anhaltenden Symptomen teilten.
3) Die italienische Forscherin @elisaperego78 verwendete als erste den Begriff "#LongCovid". Diese virtuelle Mobilisierung fรผhrte dazu, dass Medien und ร„rzte begannen, das Thema ernst zu nehmen, wรคhrend andere es ablehnten.
Read 13 tweets
Jun 2
Ron Davis: "25% #MECFS patients have MS."

GeNeuro: "25% of longhaulers have a reactivation of the HERV-W protein."

My logic:
In ME: EBV reactivates HERV-W, and this leads to MS.
In LC: Sars-Cov-2 leads to EBV reactivation, EBV reactivates HERV-W, resulting in MS.

#LongCovid
Cumulative Roles for Epstein-Barr Virus, Human Endogenous Retroviruses, and Human Herpes Virus-6 in Driving an Inflammatory Cascade Underlying MS Pathogenesis

frontiersin.org/articles/10.33โ€ฆ Image
Read 6 tweets
May 2
#PostCovid #LongCovid #MECFS

1) Sportmedizinische Erkenntnisse zu Post Covid (Uniklinik) Mainz. Prof. Dr. Dr. Peter Simon: "Problem liegt darin, dass das Blut nicht ausreichend zirkuliert und dadurch nicht genug Sauerstoff zu den Geweben transportiert wird." Image
2) Chronische Erschรถpfungssyndrome treten oft im Nachgang von Infektionen auf und fรผhren zu Leistungsverlusten. Die Uniklinik Mainz untersucht diese Phรคnomene und nutzt dabei Messmethoden aus dem Leistungssportbereich.
3) Die Organe funktionieren meistens normal, aber das Blut zirkuliert nicht ausreichend, was zu einem Defizit an Sauerstoffaufnahme ins Zielgewebe fรผhrt. Die Folge sind Leistungsverluste, wenn der Kรถrper zu viel arbeiten muss.
Read 9 tweets
May 1
#LongCovid #MECFS #PEM
National Geographic:
1) PEM ist ein Hauptmerkmal von ME/CFS und LongCovid, das sich nach viraler Infektion manifestiert. Betroffene leiden unter massiver Erschรถpfung und haben eine geringere Lebensqualitรคt als Krebs-, Schlaganfall- und MS-Patienten.
2) #PEM-Symptome variieren stark und kรถnnen von Bettruhe รผber grippeรคhnliche Symptome bis hin zu Sprachstรถrungen reichen. Die Prรคvalenz bei #LongCovid-Patienten ist schwer zu bestimmen, da es keinen offiziellen Diagnosecode gibt.
3) Historisch wurde #PEM als psychologische Angst vor Bewegung abgetan. Therapieansรคtze mit stufenweiser Steigerung der kรถrperlichen Aktivitรคt waren jedoch oft schรคdlich fรผr die Patienten. Trotzdem wird Bewegung noch hรคufig bei #LongCovid Patienten verschrieben.
Read 10 tweets
May 1
#LongCovid #MECFS #PEM #GET
1) Laut National Geographic zeigt eine Studie, dass anhaltende COVID-Symptome bei LongCOVID-Patienten durch kรถrperliche Aktivitรคt verschlimmert werden kรถnnen. Viele Betroffene leiden an chronischer Erschรถpfung und anderen Symptomen.
2) Lange Zeit rieten Experten COVID-Patienten, sich kรถrperlich zu betรคtigen, um ihre Genesung zu beschleunigen. Neue Studien zeigen jedoch, dass dies kontraproduktiv sein kรถnnte, vor allem bei #LongCovid-Patienten.
3) Die Ursachen von #LongCovid sind noch nicht vollstรคndig verstanden. Vermutungen reichen von einer anhaltenden Viruslast im Kรถrper bis hin zu einer Fehlfunktion des Immunsystems, die eine Entzรผndungsreaktion auslรถst.
Read 8 tweets
Apr 29
#LongCovid #MECFS #Covid

1) The 1918-1919 influenza pandemic, known as the Spanish flu, led to persistent and unexplained central nervous system symptoms, such as parkinsonism, catatonia, and encephalitis lethargica.
2) These symptoms, often lasting for years, included loss of energy, apathy, and melancholia. Poet Robert Frost, after recovering from a severe bout of the Spanish flu, described the lingering effects, questioning his strength to even write a letter.
3) This flu left a trail of lowered vitality, nervous breakdowns, and other complications affecting thousands of people. The aftermath of the Spanish flu caused widespread suffering, leaving widows, orphans, and dependent elderly individuals in its wake.
Read 5 tweets

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