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Lieuwe Bos - Acute Pulmonary Medicine Profile picture
Lieuwe Bos - Acute Pulmonary Medicine
@Acute_Pulmo_Med
Clinician/researcher. All about acute pulmonary medicine. #ARDS #Pneumonia #POCUS #COVID. #R Nerd. #pedawan #zentensivist
May 16, 2020 • 9 tweets • 6 min read
Supposedly, #COVID19 patients who are put on a ventilator do terribly and are very likely to die. You’ve probably seen the headlines with 88% mortality.

A #tweetorial on the actual mortality of #COVID19 on the #ICU

independent.co.uk/news/world/ame… Before we start, consider the “normal” mortality rate for a patient with acute respiratory failure on the ICU. Probably the best study to assess that is LUNG-SAFE. 50 countries. 4499 pt with ARF. 3022 #ARDS. ICU mortality = 34%.

jamanetwork.com/journals/jama/…
May 13, 2020 • 9 tweets • 5 min read
The promised #Tweetorial on validation of #COVIDー19 phenotypes that we published @AnnalsATS

But before we start.

Disclosures:
- I'm a splitter and 💕 phenotypes
- If physiology can teach us; I'm all for it!
- But, data and physiology should converge

What we know:
- #ARDS can be split into #phenotypes
- But, uncertain therapeutic implications



- #COVID-19 might be split into phenotypes as well
- But, ☝️based on #physiology with little data to back it up.