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Costantini Pascal Profile picture 1 subscribed
Dec 25, 2022 5 tweets 1 min read
"The Seven Daughters of Eve" was recently recommended to me. Thoughts, anyone?

It is a semi-fiction about the principles of genetics and human evolution, especially the mitochondrial DNA, and how the analysis ancient DNA genetically link modern humans to prehistoric ancestors. Do you know that in nearly all mammals, our mitochondrial DNA (mtDNA) is 100% from our mom?

Defects in mtDNA can lead to various mitochondrial diseases ranging from LHON (a type of eye disease), MELAS to Parkinson's.
Dec 24, 2022 4 tweets 1 min read
With more affordable sequencing made possible by companies such as $ILMN, genetic service companies such as 23andMe and DNAfit can now provide services as cheap as $100. And there comes the rise of personalised nutrition and skincare products. According to a market analysis report, the global biotech ingredients for beauty care market size was valued at $1.61 billion in 2019 and is expected to grow at a compound annual growth rate (CAGR) of 9.3% and reach $3.01 billion by 2027.
Sep 17, 2022 5 tweets 3 min read
An Israeli biotech company, Renewal Bio that recently created mouse embryos using stem cells, has announced plans to make human embryos to harvest tissue for organ transplants and anti-aging procedures.

#Stemcells #biotech #biology #Syntheticbiology #Aging #transplant The scientist behind the work clarified that:
The synthetic embryos were not "real" embryos and did not have the potential to develop into live animals. But that is partly because they don't have the technology, right now, to do so.
Sep 17, 2022 4 tweets 4 min read
$NTLA and $REGN report initial data from ph1 study of #ATTR for NTLA-2001. All patients across the two doses showed 92-94% TTR reduction at day 28.
#crispr #genomics #genetherapy #biology #biotech At both dose levels, $NTLA-2001 was generally well tolerated. 2 patients reported transient infusion reactions, which was the only observed treatment-related adverse event.
Sep 13, 2022 7 tweets 6 min read
The US Govt just announced and EO for advancing #biotechnology and #biomanufacturing for a #Sustainable , safe and secure #bioeconomy.
There are 11 areas they will be looking to fund and develop within this niche.
Read the full article here - whitehouse.gov/briefing-room/… Here is a quick summary:
1) Coordinate investment in key R&D areas to further societal goals
2)Foster a biological data ecosystem, while adhering to principles of security, privacy, and responsible conduct of research