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Catie Oldenburg Profile picture
Catie Oldenburg
@CatieOldenburg
ID epidemiologist, associate prof, Program Director for PhD in Epi @UCSF. RCTs, NTDs, peds ID, AMR. Rescue 🐈‍⬛ & 🐕 mom. Opinions my own. She/her.
Jul 16, 2021 • 10 tweets • 4 min read
Our #RCT of #azithromycin vs placebo for outpatient #COVID is out today in @JAMA_current

Tl;dr – azithromycin doesn’t help improve symptoms in outpatients with COVID and might make things worse, so don’t use it. 1/n

jamanetwork.com/journals/jama/… Image Why did we do this study? Azithromycin was identified early on as a potential candidate for COVID (+/- HCQ). Although it’s relatively safe, antibiotic use causes antibiotic resistance, and unnecessary widespread use of an antibiotic is a bad call. We need to know if it works. 2/n
May 19, 2020 • 5 tweets • 2 min read
An evaluation of mass #azithromycin distribution on respiratory #virome suggests children have ⬇️non-SARS coronavirus viral load in communities receiving azithromycin compared to placebo. These findings are intriguing, with some important considerations.
academic.oup.com/cid/advance-ar… This is a non-prespecified analysis from the #MORDOR study. These data pre-date COVID19 emergence by years. Most importantly, this paper does not say anything about whether azithromycin does or does not work for COVID19.
May 18, 2020 • 18 tweets • 5 min read
I have a feeling we’ll be seeing a lot of #RegressionDiscontinuity (specifically, interrupted time series) studies evaluating effects of #COVID19 restrictions on all kinds of outcomes. Some thoughts on when RD can be useful and why it might not always be a great idea. 1/n RD is a method that can be used to evaluate effects of exposures when a continuously measured variable has a cutoff value that can be used to assign treatment (or other exposure) status to those just above or below the threshold. 2/n
ncbi.nlm.nih.gov/pmc/articles/P…
Sep 25, 2019 • 8 tweets • 3 min read
A journal is threatening to take me personally to collections for an unpaid balance on a manuscript I wasn't the corresponding author on. Really? Threaten my personal credit history for unpaid work which you charge me to publish (a journal also for which I referee for free)? 😡 Not going to name the journal (as @evolscientist pointed out, it's the publisher not the journal doing this). Not going to name publisher just yet. Mostly wanted to point out how broken the academic publishing system is, and how awful it feels to be in a situation like this.