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Shima Ghavimi Profile picture
Shima Ghavimi
@ShimaghavimiMD
#PrecisionMedicine #IBD #ColonCancerPrevention
May 1, 2022 • 56 tweets • 32 min read
Intestinal Ultrasound
#GITwitter #MedEd

We will start with normal Normal #IUS #anatomy superficial mucosa (white) ... #IBDtwitter

In ileocecal #Crohn’s disease, typically all bowel wall layers are involved. #IUS shows marked mural thickening, predominantly in the terminal ileum, cecum & appendix can also be involved.

🔗: ncbi.nlm.nih.gov/pmc/articles/P… Image
Jul 31, 2021 • 10 tweets • 3 min read
Recurrent Frameshift Neoantigen Vaccine Elicits Protective Immunity With Reduced Tumor Burden and Improved Overall Survival in a Lynch Syndrome Mouse Model #GITwitter
#PrecisionMedicine

gastrojournal.org/article/S0016-… frontiersin.org/articles/10.33…
Jul 29, 2021 • 5 tweets • 2 min read
UECN is likely an important mechanism in development of aneuploid tumors and could be therapeutically targetable.

nature.com/articles/s4158… Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition

nature.com/articles/s4158…
Jul 14, 2021 • 14 tweets • 40 min read
#APC #TumorBoardTuesday #GITwitter #LiverTwitter #PrecisionMedicine #ColonCancer #oncology @ASCO @TumorBoardTues @CCAlliance @GeneticsSociety #Genetics #Genomics
Many of the mutations happen in the MCR region, WE should investigate the Armadillo Repeats regions for therapeutics Image #BRAF #PrecisionMedicine #Genomics #TumorBoardTuesday #GITwitter #LiverTwitter #MedEd #oncology @ASCO @GeneticsSociety @TumorBoardTues #Genomics Image