Discover and read the best of Twitter Threads about #oncology

Most recents (24)

In JAMA Oncology today, the "debate" continues.

Should hospitals do MORE or less to help people with #cancer avoid severe outcomes from COV1D?

I'll take you through each article! 🔁

1/… Graphic of 4 articles in JA...
Dr. @drlennardlee and colleagues found that people with #cancer had diminished vaccine antibody response, leading to breakthrough infections and hospitalizations.

2/… Selected graphs. Diminished...
Dr. Lee's study was one of the best I've read in a long time, so we wrote an Editorial building on it.

We offered 10 tips for hospitals to provide people with #cancer with more comprehensive supports.


Read 14 tweets
Classically placed in the arm
May be placed in the leg (eg in #pediatrics /neonates – which may then terminate in the infrarenal IVC/iliacs)
#criticalcare #cardiovascular
- Lower infection rate then central lines
- Used in the outpatient setting
- Can be used for several weeks to months
- Duration of PICC lines may be from 4 weeks to 6 months
(although they have been known to be functional for more than 300 days)
Read 20 tweets
My 3 year old daughter Lila was recently diagnosed with a VERY rare and aggressive type of #leukemia.

👉 It’s potentially treatment resistant… AND

👉 Requires a bone marrow transplant.

A🧵with all the details we have so far 👇

Please @Twitter help me save my little girl. Image
First, some background:

👉 A month ago, Lila was diagnosed with “acute undifferentiated leukemia” (AUL) by her docs at @ChildrensLA

👉 Last week, we found an unrelated marrow donor who’s a perfect “10/10” match (thx to @BeTheMatch ) and they have agreed to donate. 😭
👉 But just yesterday, we learned Lila’s first cycle of chemo failed. 🥺

Before Lila can get the transplant, we have to get her into remission first.
Read 17 tweets
1) Welcome to a new #accredited #tweetorial, "Utilizing Immunohistochemistry Testing, Biomarkers, and Targeted Therapeutics to Optimize Outcomes in Patients with NSCLC," featuring the highlights of a symposium presented at the #ESMOIO22 congress.
@myESMO #LCSM #FOAMed Image
2) The faculty for this outstanding program were @peters_solange (Chair) 🇨🇭, @HosseinBorghaei 🇺🇸, Natasha Leighl MD 🇨🇦, and @dplanchard 🇫🇷. A truly international roster of experts in #oncology!
Don't miss prior accredited courses in this space at….
3) This program is supported by an educational grant from Sanofi. Statement of accreditation and author disclosures are at
Read 24 tweets
"Doctor, the cancer has spread to the brain. Would he be alive for atleast 3-4months? There are so many things we want to do for him " 2 children enquiring about their elderly father brought in with seizures
Read on this miraculous story.
#CancerAwareness #oncology #MedTwitter
An elderly patient who was diagnosed as #lungcancer 2 years back presented to the ER at 5 pm with multiple episodes of seizures. He couldnt speak, recognise his daughters and was having slurring of speech. His consciousness levels were low
#CancerAwareness #oncology #MedTwitter
A MRI of the brain done showed one of the most tragic sights-multiple areas of the brain affected by Cancer deposits. In the image you can see them as the fluffy white spots.
#lungcancer #MedTwitter #oncology
Read 22 tweets
1/ The impact of #Covid on $PVCT’s R&D, #DrugDiscovery, and clinical development of our #HalogenatedXanthene (#HX) medical science platform and #RoseBengalSodium (#RBS) investigational drug & drug formulation pipeline. A #THREAD.
2/ This $PVCT #thread will be an ongoing one for some time. Please check back to read it again (and again), and learn more about our medical scientific history and our lead molecule #RoseBengalSodium’s journey to becoming a multi-disease, broad-spectrum, therapeutic compound.
3/ #Covid has been a deeply painful experience, to say the least, for the U.S. and the world. It also marked a turning point in the advancement and expansion of our #HX medical science platform, as well as our lead molecule #RoseBengalSodium and the investigational drugs and drug……
Read 63 tweets
1/ A $PVCT THREAD: (3) Potential 2023 read outs of preclinical data from sponsored research programs (#SRAs) in different diseases. #research. #oncology #hematology #dermatology #InfectiousDiseases #ophthalmology #WoundHealing #TissueRegeneration. #rosebengal #rosebengalsodium.
2/ $PVCT 2023 Stockholder Letter (released January 9th). . #rosebengal #rosebengalsodium.
3/ In 2023, $PVCT expects research collaborators at different academic medical institutions to read out data from their preclinical research work under newly established and existing #SRAs. #research. #rosebengal #rosebengalsodium.
Read 60 tweets
Ever planned RCT w/ PFS and OS as formal endpoints?

Ever simulated PFS and OS for same set of patients?

In both cases: How did you model the fact that PFS and OS are highly dependent? E.g. we know that PFS <= OS and P(PFS = OS) > 0.

A (long) thread - but it' s worth it!

We are very used to model dependency of an endpoint over time (= group-sequential designs) or over nested populations (= enrichment designs), b/c then it's not difficult to write down correlation between test statistics.

However, typically in trial planning PFS and OS...

are treated as if they were independent and proportional hazards (PH) is assumed for both.

We propose to model dependency between PFS and OS using an illness-death multistate model (IDM), building on the work of Meller et al (2019)…

Read 10 tweets
1/ A THREAD on what $PVCT achieved in 2022. #event #discovery #milestone #milepost. #rosebengal #rosebengalsodium.
2/ $PVCT 2023 Stockholder Letter (released January 9th). . #rosebengal #rosebengalsodium.
3/ $PVCT #clinical and #research collaborators made 6 presentations at 5 medical conferences about PV-10 for different cancers. #ENETS22 #AACR22 #ASCO22 #ISOO2022 #melanomabridge. #presentations. #rosebengal #rosebengalsodium.
Read 50 tweets
$PRTG new investor presentation out this week, worth a look through 🧵 1/26
2/26 legal disclaimer
3/26 $PRTG Investment Highlights
Read 26 tweets
Is #LiquidBiopsy the Future of #Cancer #Diagnostics? 💉🧬🤔

Standard cancer detection tests are done with #tissuebiopsies.🧫

These are invasive, risky, and expensive as they require an endoscope and open surgery.

An alternative approach to this is Liquid Biopsy which is performed by drawing blood.🩸

Liquid biopsy is an innovative solution to #cancerdetection.

▪️They use a much smaller sample and have a quicker turnaround for results compared to tissue biopsies.

▪️They are more advantageous in detecting a metastasized tumor - when cancer has spread to multiple sites.

Read 5 tweets
[1/5] #Glioblastoma comprises 49.1% of all primary malignant brain tumors and approximately 12,000 cases are diagnosed each year in the US. A recent study In @JAMAOnc investigated whether the addition of an...
[2/5] autologous tumour lysate-loaded dendritic cell vaccine (DCVax-L) to the traditional standard of treatment (#surgery, #radiotherapy, and #chemotherapy) for glioblastoma prolonged survival.
#Neurology #Oncology #brain
[3/5] DCVax-L was found to be promising in extending survival for patients with newly diagnosed glioblastoma who are also receiving standard treatment for their disease.
#HealthcareNews #medicine #MedEd
Read 5 tweets
Middle aged patient presents with insidous onset, progressively worsening SOB.

Chest is full of wheezing and creps.

What is this?

#MedTwitter Image
This is the HRCT thorax. Image
This is a biopsy proven adenocarcinoma.

No air bronchograms
Multiple coalescing nodules of various sizes --> s/o cannonball metastases.

#tuberculosis Image
Read 7 tweets
We at HCC are so proud of our team and participating centers. 6 abstracts of our collective work have been accepted for #ASH22. If you wish to be a part of this movement either as an individual or as a participating institution, do visit us at
#2976 Prognostic Factors and Outcomes of Adolescent and Adult Burkitt Lymphoma and Leukemia from a Low-Middle Income Country: An Experience from Hematology Cancer Consortium…
Read 21 tweets
Sponsored by @Roche,
I would like to share a Tweetorial about recent important advances in the management of advanced/metastatic triple negative breast cancer (mTNBC)

#Tweetorial #Oncology #Cancer #Diagnosis #TNBC #Immunotherapy #PDL1
TNBC is a challenging disease to treat due to its aggressive behavior, heterogeneity, and the lack of universal actionable targets. mTNBC is commonly diagnosed at a younger age than other BC subtypes and its prognosis is poor, with a median survival of <2 years.
Advanced TNBC can result from recurrence after treatment in the early-stage disease setting, or it may be diagnosed at initial (de novo) presentation
Read 12 tweets
Welcome everyone to our 2nd Pediatric on Squares Board Review Course
We are starting today until the coming 8 days
Hope it’ll be helpful and enjoyable course
✏️ Note that you still can join and register on the course with accessibility to all recorded session until 27th of August ImageImage
Day 1
1st session: Pulmonology Review
By Dr. Bassem Kurdi @Bassemkurdi

#Pediatric #Pulmonology #MCQ ImageImage
Day 1
2nd session: Keys to Answer MCQs
3rd session: Neonatology review
By: Prof. Abdulrahman Alnemari @aalnemri
#Pediatric #Neonatology #NICU #MCQ ImageImage
Read 23 tweets
1/n) ICMR released Standard Treatment Workflows (STWs) volume 3 which contains 11 specialties with 52 diseases. It is accessible at and on the Mobile App.
@MoHFW_INDIA @DeptHealthRes #STW
2/n) Standard Treatment Workflows (STWs) on #𝐃𝐞𝐫𝐦𝐚𝐭𝐨𝐥𝐨𝐠𝐲 containing 14 major diseases. It is accessible at and on the Mobile App. @MoHFW_INDIA @DeptHealthRes
3/n) Standard Treatment Workflows (STWs) on #Endocrinology containing 06 major diseases. It is accessible at and on the Mobile App. @MoHFW_INDIA @AyushmanNHA @WHOSEARO #diabetes
Read 12 tweets
The journey to the diagnosis of Sweet syndrome and its differentials is too sweet 🍬🍩🍫

Let's explore the sweetness.

@rabihmgeha @DxRxEdu @Sharminzi @DrCindyCooper @jackpenner @sargsyanz @rav7ks @RebeccaEBerger @RosenelliEM @CPSolvers @MithuRheum #MedTwitter #rheumatology
#1 Malignancies & Sweet syndrome

- AML (common)
- MDS (common)
- MM
- Hodgkin's lymphoma
- Mycoses fungoides
- Cutaneous T-cell lymphoma
- Hairy cell leukemia
- Solid tumors

#oncology #hematology #MedTwitter
#2 Autoimmune disorders & Sweet syndrome

- IBD (common)
- Behcet (common)
- SLE (common)
- RA (common)
- Relapsing polychondritis
- Sarcoidosis
- Sjogren's
- Familial Mediterranean fever
- Undifferentiated connective tissue disease
- Erythema nodosum

#rheumatology #MedTwitter
Read 8 tweets
A *brutal* snapshot of #COVID19
in cancer patients
⚠️75 of 416 patients died
*⃣ 61.3% of these deaths were due to
COVID-related complications… #scicomm #snrtg #openscience #immunology #oncology #immunocompromised
Please 💉get vaccinated💉
to protect yourself
AND the immunocompromised
from Sars-Cov-2.
The immunocompromised, immunosuppressed, and immunodeficient are taking a beating from this virus.
A f-cking beating.
Read 4 tweets
The more I think about airlines abruptly allowing mask removal w/o warning—mid-flight for many—the angrier I get. People who are #immunocompromised had no choice not to travel or to upgrade their protection at that point. Some will go on to die. As an oncologist, I am enraged.
If you haven’t had #cancer or been a caregiver to someone with it, you don’t know how much people endure. I’m a breast oncologist. Our patients have breasts amputated, lose their fertility, go bald, risk nerve damage, infection, & more from chemo, because they want to live.
The fact that the airlines made a corporate decision to drop masks w/o warning—any airline could’ve chosen to give crew/passengers hrs or days of notice—disgusts me. For an industry that prides itself on safety, this is a fail.

@Delta @united @SouthwestAir @AmericanAir @JetBlue
Read 10 tweets
🚨 #CME Thursday 🚨

This week at #TumorBoardTuesday @W_Park_MD discussed FGFR inhibitors in #BiliaryTractCancer #CCA...and how to find FGFR fusions!

Check out the questions below, and tap the link to claim your free #CME...and stay tuned for a special edition of case wrap up! Image
#PostTest Q 1️⃣ #CME #TumorBoardTuesday

🤔 What is a molecular biomarker for an FDA approved🎯💊in #Cholangiocarcinoma

#OncTwitter #GeneTesting #CCA
#PostTest Q 2️⃣ #CME #TumorBoardTuesday

🤔 To detect 🧬 gene rearrangement what is the preferred method❓

#OncTwitter #GeneTesting #CCA
Read 14 tweets
1/9 #TumorBoardTuesday Thursday Case Wrap Up🎀

⏰ for #TBT Case Wrap Up!

We looked at dx and tx of Carcinoma of Unknown Primary (#CUP), including how 🧬 can change tx.
There was a lot to learn–we captured what we could of the discussion here:…
2/9 #TumorBoardTuesday Thurs Case🎀
#CUP is complicated!
✅Comprehensive approach needed, including:
H&P,🔬, 🩻, 🧬
✅Overall inc of CUP is ⬇️–many liver CUP being recognized as cholangio
✅NGS can help augment the w/u
✅STK11= frequently mut in lung; ⬇️response to IO Image
3/9 #TumorBoardTuesday Thursday Case🎀

@LaurenBzak’s case: Pt p/w solitary 🧠 lesion ➡️ poorly diff adenocarcinoma. But–not a primary CNS malignancy. NOTHING outside 🧠on CT or PET.

🧐What should we do next?

👍Detailed H&P (smoking hx)
Read 12 tweets
Le nanoparticelle diventano invisibili per essere più efficaci contro i tumori: un nuovo sistema per veicolare i farmaci. Un argomento FIGHISSIMO. Segue un thread. 1/n 🧵
Come pubblicato dai ricercatori dell'università Sapienza di Roma, questo approccio sarebbe in grado di ingannare il sistema immunitario permanendo a lungo nell’organismo e superando i limiti attuali dei liposomi. 2/n
Com'è fatta e come funziona la nanoparticella biomimetica? ProteoDnasoma è il nome della particella biomimetica messa a punto dai ricercatori nello studio condotto in collaborazione con la University of Technology di Graz in Austria e la Utrecht University in Olanda. 3/n
Read 16 tweets
Fantascienza? No. Un case report mostra una regressione di malattia in un paziente oncologico a seguito della vaccinazione anti-COVID. Un breve thread per parlarne. 1/n 🧵
#COVID19 #oncology
La regressione del tumore può verificarsi a seguito di un'intensa risposta immuno-infiammatoria. E com'è possibile? 2/n
Nel case report viene riportata una regressione spontanea del carcinoma mioepiteliale delle ghiandole salivari metastatico in un paziente, a seguito della vaccinazione con mRNA-1273 COVID-19. 3/n
Read 9 tweets

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