Almost exactly 17 years ago to the day, fresh off my 100 days post-bone marrow transplant for acute lymphoblastic leukemia, I had a visit from Aly Friedman. My flirting was pathetic, but endearing enough that we started dating. We’ve now been married over 12 years. #yourvelocity And today, as part of the virtual @velocity_ride, our 5 year-old daughter wanted in on the fun! #yourvelocity

This is my last week at @sloan_kettering after 8 1/2 years. No one had as much impact as @rosslevinemd, and so with my final MSK tweetorial before @cohesinlab moves to @columbiacancer to start @cohesinlab, a few of my favorite memories and pearls of wisdom from @rosslevinemd 1/25 In 2016 during the Vice President’s @CancerMoonshot initiative, there was a planned visit for @JoeBiden to come to @sloan_kettering. I heard the original plan was to visit the @CharlesSawyers lab, but Secret Service preferred the RRL building. 2/25

The Viny lab @cohesinlab is looking for motivated and courageous postdoctoral scientists to join our small but mighty group. @cohesinlab will open next month at @ColumbiaMed @columbiacancer & @CSCIColumbia (1/15) We will focus on employing new and existing mouse models, primary patient samples, and state-of-the-art epigenomic/transcriptional assays for assessing 3-dimensional chromatin structure in the malignant context. These are the core principles by which we will operate: (2/15)

1/ Sometimes coincidence makes you take a beat. Today is day +6,209 (17 years) since my allogeneic bone marrow transplant for relapsed Acute Lymphoblastic Leukemia. Today I am rounding as the inpatient leukemia attending. I brought cake. 2/ And I’ve tweeted my annual transplant anniversary before—worthy of much celebration—but this year is different. Even different from my 10 years cancer free as a @sloan_kettering fellow on the BMT service.

1/ I’ve been thinking about this pledge and how best to take steps towards fighting systemic racism—while I don’t yet have a lab, like @SantoshVardhana I want to identify tangible actionable ways to make a difference. He and @leowanglab and @juliamaxson inspire me to plan now

https://twitter.com/rosslevinemd/status/1269264023385710592

2/ I pledge to bring in a URM high school or undergraduate for a paid summer internship who might not orherwise get #STEM exposure and then avail myself and my #WhitePrivilege to help mentor/navigate the system

1/n Today is day 28 away from wife and daughter. The first half of this separation was spent as leukemia attending @sloan_kettering for both #COVID19 and non-COVID hospitalized patients before cohorting strategies began and while guidelines for stewardship of #PPE were in flux 2/ We continued to give world class care to our patients, but that meant high risk exposures to my team and myself. Friends and colleagues with cough or other concerning symptoms were sent immediately for testing thanks to the amazing laboratory medicine dept efforts by @EBabady

1/ A wonderful “state of the physician scientist” training overview of what programs are doing to support us along the continuum of medical education and training. Hard to break in unless starting in a dedicated program or with grant support.

https://twitter.com/vumc_medpstp/status/1227056645131378698

2/ With T32/F31 @NIHgrants only available for MD/PhDs, the entry point for non-PhD MDs took a major hit with the ending of the @HHMINEWS HHMI Med Fellows program. For me this was a major accelerator.

Off to @OHSUKnight to talk @cohesinlab and cancer (and coffee and wine and food) and meet with amazing faculty like @juliamaxson @DrTedPBraun Jeff Tyner, Brian Druker and others! So excited to go but this one hates when I leave... #lifeonthejobmarket Oh @travelportland you are off to a GREAT start! @stumptowncoffee

Very excited to share my work on Stag2, chromatin architecture, and effects on hematopoiesis! Join me in a @MedTweetorials of why this is so important! @CellStemCell cell.com/cell-stem-cell… The cohesin complex is comprised of structural proteins (Smc1a, Smc3, Rad21) bound to a Stag protein. We and others have described that alterations of each affect hematopoietic self-renewal and differentiation.

A #tweetorial from @RossLevineLab and colleagues on our new preprint online today at @biorxivpreprint from @sloan_kettering biorxiv.org/content/10.110… 1. The cohesin complex is comprised of structural proteins (Smc1a, Smc3, Rad21) bound to a Stag protein (most commonly Stag1 or Stag2). The entire complex is targeted by somatic mutations in myeloid malignancies, whereas STAG2 is most prevalent across all cancer @cohesin_papers

It was THAT kind of party! #ASH18 #rossapalooza #Dameshek #LevineLab #ASH18 #Ink @TrowbridgeLab @Bowmaniacs_Lab