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Audrey Odom John MD PhD Profile picture
Audrey Odom John MD PhD
@odomjohnlab
@odomjohnlab@med-mastodon.com Physician, scientist, mentor, mom, Chief @CHOP_ID | Lab goals: new ways to diagnose and treat malaria | views my own | she/her
Aug 2, 2020 • 5 tweets • 3 min read
Oh, look at these VERY GOOD DOGS! 🐶

Covid-sniffing puppers from PennVet @pennvet @PennVetWDC, happily working hard on our pediatric SARS-CoV2-infected samples! @CHOP_ID @CHOP_Research

nbcnews.com/nightly-news/v… Image The whole video is just adorable - look at their tails go! (And the data is looking good, too)

nbcnews.com/nightly-news/v…
Jul 19, 2020 • 31 tweets • 19 min read
Day 1 of #idsaracialequitychallenge:
@NPR Shortwave Podcast on understanding unconscious bias:
npr.org/2020/07/14/891… Day 2 of #IDSARacialEquityChallenge. Today, I’m borrowing these great podcast recs:



@IDSAInfo @PIDSociety #dothework https://t.co/SgPhfwULci
Jun 11, 2020 • 8 tweets • 5 min read
So excited to share some new work @PLOSPathogens from our group – on zoonotic staphylococci!

So, how’d we get from #malaria parasites to pathogens of puppies 🐶?

🧵

journals.plos.org/plospathogens/… We’ve been collaborating w/Cindy Dowd at GWU (@GWtweets) making new antimalarials called MEPicides = cool prodrugs that target the DXR enzyme of the MEP pathway -- an essential biosynthetic pathway that humans and other mammals just don’t have/2

see:
nature.com/articles/s4159…
Nov 27, 2019 • 5 tweets • 4 min read
#IDTwitter, a clinical pearl from d2 @CHOP_ID

Retropharyngeal abscess (RPA) is increasing in incidence (data from 2000 - 2012).

How likely is MRSA? Do you need to empirically cover? /1

academic.oup.com/jpids/article/… @CHOP_ID To guide us, fortunately we have really nice data - from our own institution (from otolaryngologist Lisa Elden @CHOP_Research)!

A consecutive case series review of 178 kids with deep space neck infections:

…s-sagepub-com.proxy.library.upenn.edu/doi/full/10.11…

/2
Nov 26, 2019 • 7 tweets • 13 min read
THREAD

A little parasitology #MedEd inspired by d1 @CHOP_ID:

Diarrhea after contact with baby cows? Think #cryptosporidiosis! 💩+ 🐄 = #crypto

The other big exposure risk? Recreational water, especially pools and lakes 🏊‍♂️

cdc.gov/mmwr/volumes/6…

/1 Image @CHOP_ID Calf exposure is such a big risk b/c calves are very likely to have #crypto. My favorite outbreak is this 2013 overturned cattle truck carrying 100s of calves. RR for diarrhea 3.0 in first responders who "carried calves":

cdc.gov/mmwr/preview/m…

/2
Nov 15, 2019 • 5 tweets • 2 min read
Let me tell you about our newest preprint – a story of heat shock and prenylation in Plasmodium falciparum!
biorxiv.org/content/10.110…

[Thread]
Most people with malaria get fever - how do malaria parasites survive that stress? /1 First of all, P. falciparum has a ton of heat shock proteins. In particular the DnaJ/Hsp40 family is very expanded – there are 49 Hsp40 family members in P. falciparum!! /2

Reviewed here: mdpi.com/2218-273X/9/7/…
Jul 18, 2018 • 4 tweets • 2 min read
New article on the "leaky pipeline" of #WomeninSTEM. Once female faculty get their first big grant, they tend to stay in science - yay! But...[thread]
pnas.org/content/early/… Senior author Greenberg is quoted in @nature: "[Women] should realize that, sure, it is not easy in academia, but they are not going to have any more difficulty than men once they get their first grant.”
nature.com/articles/d4158…
Apr 23, 2018 • 4 tweets • 1 min read
Big display on the history of biochemistry at #ASBMB2018 --and this is the only woman pictured. Really guys?? ImageImage Of course, there is not a single person of color