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Shantanu Gaur M.D. Profile picture
Shantanu Gaur M.D.
@shangaur
Pittsburgher, @Harvard '08, @HarvardMed, @GeneticAlliance Council, co-founder & CEO @alluriontech. Views my own.
May 26, 2020 • 15 tweets • 8 min read
1/
UK PM Boris Johnson has declared a “war on fat” after confronting the role his #obesity played in his harrowing encounter with #COVID.

In this #tweetorial, we’ll take a closer look at the studies sounding the alarm in the UK.

#medthread #MedTwitter

thetimes.co.uk/article/boris-… 2/
Ho et al. (pre-print) studied 428,225 subjects in the @UK_Biobank of which 340 had confirmed #COVID.

BMI had a risk ratio (RR) of 1.24 (per 1SD). Obesity itself had a RR of 2.29.

medrxiv.org/content/10.110…
Apr 20, 2020 • 11 tweets • 6 min read
1/
 #Obesity and #COVIDー19 have been in the headlines recently.

The link between the two is now undeniable.

Let’s take a look at WHY they are so tightly linked molecularly, physiologically, and anatomically in this #tweetorial.

#medthread #medtwitter

nytimes.com/2020/04/16/hea… 2/
 We learned quite a bit about obesity and viral infection in 2009 during the #H1N1 epidemic. Obesity led to:

🔼risk of ICU admission
🔼viral shedding
🔼recovery times

But WHY?

ncbi.nlm.nih.gov/pmc/articles/P…