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Where would we be without the US @COVID19Tracking project? Besides tracking testing everywhere, today a preprint review of 10 serology tests: "very heterogeneous performance"
covidtestingproject.org/index.html
dropbox.com/s/cd1628cau092…
@USCF @czbiohub @UCBerkeley @igisci 🙏
Good to see @apoorva_nyc write about this and acknowledge their exceptional effort
nytimes.com/2020/04/24/hea…
Clarification on the 2 projects that arose out of voids:
@COVID19Tracking tracks testing, essentially replacing @CDCgov for this important function
and
covidtestingproject.org/index.html Covid-19 Testing Project (no @twitter handle), taking on @US_FDA role
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Eric Topol
@EricTopol
Coming down from the plateau a bit.
Best sign I've seen for the US fatality curve in 2 weeks
Please keep coming down
Mitigated by a rise in US cases today, back well over 2,000 again. Let's just hope that's a bad day on the way to better ones. Still very concerned about states that are now/soon opening leading to a rebound.
That graph @COVID19Tracking is on deaths, not cases, as I mistakenly wrote above.
Read 4 tweets
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Eric Topol
@EricTopol
A break from #SARSCoV2 to another challenge—very early diagnosis of #cancer. Just released @ScienceMagazine is a study of 10,000 women using a blood test (#genomics, proteins) and PET imaging w/ very high specificity of diagnosis (and low sensitivity)
science.sciencemag.org/content/early/…
As far as I know, this is the 1st prospective study to show very early diagnosis of #cancer in healthy people w/o symptoms and curative potential. For that it is groundbreaking. The authors acknowledge many limitations and the further work to be done
While a blood test + PET for very early #cancer detection in a large cohort healthy women was a highlight of the day, a hard look at the numbers are warranted. Especially false positives. @jocelynkaiser @ScienceMagazine reviews the caveats here sciencemag.org/news/2020/04/b…
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Eric Topol
@EricTopol
A bit about children with #COVID19.
1. It's very true that they're much less likely to get very sick
wsj.com/articles/conse…
by @wsj_douglasj
2. In this extensive contact tracing report from yesterday thelancet.com/journals/lanin… @TheLancetInfDis secondary infections ("attack rate") were much more mild in children, but also without fever and symptoms that could be missed
3. All of the studies to date suggest that viral load in individuals who are infected w/ #COVID19 are similar, irrespective of symptomatic status
That also suggests that many children are capable of being asymptomatic carriers for spread
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