Profile picture
, 12 tweets, 6 min read
My Authors
Read all threads
IMPORTANT: #COVID19 and #VitaminB: Vitamin B plays a vital role in cell functioning, energy metabolism, activation of innate & adaptive immune responses, reduce cytokine levels, improves respiratory function, and can reduce the length of stay in hospital. ncbi.nlm.nih.gov/pmc/articles/P…
1. Thiamine or B1: As antibodies, & importantly T-cells, are required to eliminate the #SARS_CoV_2 virus, thiamine deficiency can potentially result in inadequate antibody responses, and subsequently more severe. Factsheet attached.
link.springer.com/chapter/10.100…
2. Vitamin B2 (Riboflavin): Riboflavin & UV light has been shown to be effective against the MERS-CoV virus, could also be helpful against SARS-CoV-2. Also decreased the infectious titer of SARS-CoV-2 below the limit of detection in human blood.
journals.plos.org/plosone/articl…
3. Vitamin B3 (Niacin): Niacin acts as a building block of NAD & NADP. NAD+ has immunomodulatory properties, decreases pro-inflammatory cytokines, IL-1β, IL-6 & TNF-α. Evidence indicates that targeting IL-6 controls the inflammatory storm in COVID-19.(1/2)
sciencedirect.com/science/articl…
In addition, niacin reduces viral replication (vaccinia virus, human immunodeficiency virus, enteroviruses, hepatitis B virus) & strengthens the body’s defense mechanisms. (2/2)
ncbi.nlm.nih.gov/pmc/articles/P…
4. Vitamin B6 (Pyridoxine): Researchers reported that vitamin B6(as well as B2 & B9) upregulated IL-10, a powerful anti-inflammatory & immunosuppressive cytokine which can deactivate macrophages and inhibit antigen-presenting cells & T cells.
mdpi.com/1422-0067/20/1…
5. Vitamin B9 (folic acid, folate): Recently, it was noted that folic acid was able to inhibit furin, preventing binding by the SARS-CoV-2 spike protein, preventing cell entry and virus turnover.
chemrxiv.org/articles/prepr…
6. Vitamin B12 (cobalamin):
a. A recent study showed that methylcobalamin supplements have the potential to reduce COVID-19-related organ damage and symptoms. (1/2)
gsconlinepress.com/journals/gscbp…
b. A clinical study in Singapore showed that COVID-19 patients who were given vitamin B12(500 μg),vitamin D(1000 IU) & magnesium had reduced COVID-19 symptom severity & supplements significantly reduced the need for oxygen and intensive care support. (2/2)
medrxiv.org/content/10.110…
Summary: Balanced diet plate with all important nutrients is crucial during COVID 19 and beyond. The role of nutrition in prevention, as well as recovery, is unmeasurable. Start eating well now.
@FiatLux_USA Vitamin B in COVID 19.
We have already explored the role of #VitaminD in COVID 19. But, each B vitamin has a distinct role in management of COVID19.
Missing some Tweet in this thread? You can try to force a refresh.

Keep Current with Subhasree Ray

Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

Twitter may remove this content at anytime, convert it as a PDF, save and print for later use!

Try unrolling a thread yourself!

how to unroll video

1) Follow Thread Reader App on Twitter so you can easily mention us!

2) Go to a Twitter thread (series of Tweets by the same owner) and mention us with a keyword "unroll" @threadreaderapp unroll

You can practice here first or read more on our help page!

Related hashtags

#COVID19 #VitaminB #SARS_CoV_2 #VitaminD

More from @DrSubhasree see all

Profile picture
Subhasree Ray
@DrSubhasree
As we already know that #COVID19 is majorly affecting people who are living with #Diabetes Mellitus, high BP, high cholesterol, and obesity, in this thread, the association between diabetes and infections are explained.

1. How diabetes affects the body (from head to toe). Image
2. Immunity and Diabetes: Diabetes has been associated with the reduced response of T cells, neutrophil function, and disorders of humoral immunity. Consequently, the disease increases the susceptibility to infections.
pubmed.ncbi.nlm.nih.gov/10575137/ Image
3. What are the major infections associated with diabetes?

There is clinical evidence pointing to the higher prevalence of infectious diseases among individuals with diabetes mellitus.
pubmed.ncbi.nlm.nih.gov/16007521/ Image
Read 4 tweets
Profile picture
Subhasree Ray
@DrSubhasree
IMPORTANT: New 'Bradykinin' theory in #COVID19 and target-based therapeutic intervention.

According to the latest research, Bradykinin might be responsible for major symptoms in COVID like cough, sneeze, stuffy nose, leaky blood vessels, etc.
1. Using a supercomputer, Dr. Jacobson and the team first discovered very distinct patterns in the data from the patients' bradykinin systems. Unlike cytokine, bradykinins handle infection via inflammation & generate typical symptoms of influenza & cold.
the-scientist.com/news-opinion/i… Systemic-level effects of critically imbalanced RAS and brad
2. Bradykinin inflammatory pathway in COVID-19:

COVID-19 patients' lungs include an abundance of enzymes that trigger the production of bradykinins & unexpectedly few enzymes can break it down. This causes bradykinin storm, allowing for fluid to build up around the lungs. The leaky blood vessels and lung fluid build-up in some COVI
Read 8 tweets
Profile picture
Subhasree Ray
@DrSubhasree
Making a case for #VitaminD during #COVID19: This pandemic is affecting obese, diabetics, hypertensives, malnourished & immune suppressants. In India, 82% deaths due to COVID is related to co-morbidities.

VITAMIN D is related to all these.

1. Immunity: intechopen.com/books/vitamin-…
2. Diabetes: One of the major risk factors to contract the virus, severe disease progression & mortality. Prevalence of diabetes in India is ~12% and growing. Vitamin D definiciency is associated with impaired insulin sensitivity & glucose metabolism, i.e. occurrence of diabetes.
3. Obesity: obesity is most common cause of COVID 19 deaths. The prevalence varies from 11.8-31.3%. Vitamin D deficiency causes obesity and if you are obese, you are more prone to be Vitamin D deficient. This is a 2 way relationship. (1/2)
onlinelibrary.wiley.com/doi/10.1002/dm…
Read 8 tweets

Embed code for your website

×
Follow Us on Twitter!

Did Thread Reader help you today?

Support us! We are indie developers!

This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3.00/month or $30.00/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!