Those Nerdy Girls Profile picture
Sep 24, 2020 13 tweets 4 min read Read on X
1/ Q: When will we get to herd immunity?

A: When we get a vaccine & lots of people have received it; or else, a very long time from now.
2/ Even though we have well over 30 million confirmed cases & nearly a million deaths from #COVID19 worldwide, we’re not even close to reaching herd immunity. In fact, we're not even close to the lowest estimates for herd immunity in the places that were absolutely slammed early.
3/ Most scientists think that we need around 60-70% of people to be immune to #COVID19 in order to reach herd immunity. Herd immunity happens when a virus is starved of new hosts because susceptible people are so rare in the population.
4/ We can get that herd immunity threshold a little bit lower if we’re really strategic about who is immune. For example, for pertussis (known as whooping cough), you may have noticed that recent public health campaigns focus on vaccinating grandparents.
5/ Vaccinating grandparents is important because immunity from the pertussis vaccine starts to wear off as we age. We’re protecting newborns by making sure the people around them are immune. This strategy is called cocooning.
6/ There are other strategic ways to get the effective herd immunity threshold to be a little lower, such as requiring nursing home employees to be vaccinated annually for influenza. But even with a strategic program, we probably can’t get the threshold a lot lower than 60%.
7/ We’ve been through the looking glass for 9 months, & so far about 6.9 million people in the U.S. have confirmed infections. That’s about equal to the total population of the state of Arizona.
8/ Now let's do some imagining. Let's assume that having been previously infected actually does make us immune for life (which is still an open question). Let's also assume that we've under-identified cases--in fact we've only identified 1 in every 5 cases.
9/ That means we only have another 136 million cases to go until we reach herd immunity! 136 million people is roughly the combined population of the 10 biggest cities in the U.S. PLUS the entire population of FL., OH., GA, NC., MI., NJ., VA., WA., AZ., & TN. Combined.
10/ We would also expect between 500,000 & 2 million deaths, depending on how good we are at protecting our most vulnerable from infection. For comparison, the number of deaths would be something like the total population of New Hampshire.
11/ Now, let’s say that we’re all willing to accept the *completely insane* number of deaths involved in getting to herd immunity through natural infection. (Which, for the record, we are not. That is *not* a good public health strategy.)
12/ At the current rate, we’ll reach herd immunity in… 14 years & 5 months!

When & if an effective vaccine becomes available, we’ll still need to vaccinate millions & millions of people. But when we get vaccinated, we become immune *without getting sick*.
13/ Because of this cruel math & other reasons, the only reasonable way to achieve herd immunity is through a vaccine that is effective & widely adopted.

mayocl.in/2Ezpx1q
53eig.ht/3mNygyd
go.nature.com/3j2gO6U
#Infection #Spread #Uncertainty #Misinformation

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More from @DearPandemic

Dec 22, 2022
How can I stay safe during the holidays?

➡️Think in terms of harm reduction. Don’t let the perfect be the enemy of the good.

dearpandemic.org/safe-holidays/

#covid #rsv #flu #HolidaysAreComing

1/
2/ Just in time for Christmas, #COVID is again on the rise.

#Flu and #RSV may be peaking—but remember that there are often as many cases *after* a peak as before it.

dearpandemic.org/are-cases-peak…
3/ How can we enjoy moments w/ family & friends & lower the risk of illness?

💥 Small steps you take to reduce risk are worthwhile. A little bit better…is a little bit better.

Prevention steps that work for COVID will reduce the risk of RSV, flu, & many other nasty viruses.
Read 14 tweets
May 4, 2022
1/ Q: Has almost everyone been infected with COVID by now?
A: Recent estimates suggest around 58% of the population in the US and over 70% in England have been previously infected, with BIG increases during the Omicron wave.

dearpandemic.org/numbers-infect…
2/ A recent @CDCgov MMWR report estimated seroprevalence from a convenience sample of blood collected for medical tests.

➡️Roughly 58% of Americans showed evidence of previous SARS-CoV-2 infection in their blood by Feb '22.

cdc.gov/mmwr/volumes/7…? Image
3/ ➡️ During the Omicron wave from December 2021-February 2022, this estimate increased from 33% to 58%.
➡️ Rates vary a lot by age, ranging from 33.2% for those over age 65 to 75% for those under age 18.

cdc.gov/mmwr/volumes/7… Image
Read 15 tweets
Apr 29, 2022
1/Q: Did getting exposed to fewer germs for the last 2 years weaken our immune systems?

We've been hearing this question a lot.
dearpandemic.org/fewer-germ-exp…
2/ Not likely. If your kids are suddenly getting sick a lot, this is likely due to “catching up” on exposures rather than a weakened immune system.
3/ Many families w/ young kids have been hunkered down for the better part of 2 years– a good % of a young child’s entire life. While isolation had *many* downsides, we can agree that not having to suction snot out of infant noses or clean up norovirus puke was a happy upside.
Read 18 tweets
Jan 27, 2022
1/ Q: Are cases peaking? That means it’s all downhill from here, right?

A: Sort of…. Remember that even if cases come down as quickly as they rise, there will be as many cases *after* the peak as before (think area under the curve).

dearpandemic.org/are-cases-peak…
2/ ➡️ And if the downward slope is *slower* than the rise, we will see *more* cases during the decline from a surge.
3/ Burning fast could be a silver lining of super transmissible #Omicron. Cases rose & fell quickly in S. Africa (w/ hospitalizations & deaths still lagging). The UK appears to have turned the Omicron corner. Many US states appear past their peak in cases, w/ regional variation:
Read 17 tweets
Dec 30, 2021
1/ Q: Case numbers are jumping QUICK! What should I be doing?

A: Share your gifts without sharing COVID. Helpful gestures come in many shapes.

dearpandemic.org/what-should-i-…

#Omicron #ThoseNerdyGirls
2/ One HUGE help: Cancel non-essential plans.

Unfortunately, this includes New Year’s Eve plans. The perfect storm of a new variant & holiday get-togethers is hitting communities & health care w/ FORCE! Testing is in short supply.
3/ Health care is under extreme pressure with surging cases. If you can avoid even one additional contact, you are helping. This is a temporary and urgent request (from a health care provider).

#MedTwitter #HCWs @IMPACT4HC
Read 10 tweets
Dec 21, 2021
1/ Q: Is it true that #Omicron is less severe than previous variants?

A: We HOPE so, but we don’t know yet. The evidence so far is mixed.

dearpandemic.org/is-omicron-les…
2/ We are WAY past due for some good variant news. But pinning our #Omicron hopes on a less virulent variant is not wise for 2 reasons:

1) It might not be less severe in those who are “immune naïve” (neither vaccinated nor with a previous infection—still millions of people).
3/ 2) Many more infections *even* if less severe can still lead to an avalanche of hospitalizations and deaths, and the risk of long Covid.

@AdamJKucharski raised this last December w/ the rise of Alpha:
Read 25 tweets

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