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Prof Peter Hotez MD PhD Profile picture
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17 Oct, 4 tweets, 2 min read
Thread 1/4: I haven't said it as strongly as this, but no question that White House CoV Task Force refusal to mount a national strategy, CDC suppression, and deliberate anti-science disinformation campaign are responsible for our huge loss of life. My documentation in this thread
Thread 2/4: Absence of a US national response and my call for an October 1 plan that never happened sciencedirect.com/science/articl…
Thread 3/4: The Anti-science disinformation campaign sciencedirect.com/science/articl…
Thread 4/4: Even with that, there is still hope that we can prevent American deaths later this fall and winter, here's my latest in @sciam scientificamerican.com/article/trumps…

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More from @PeterHotez

Prof Peter Hotez MD PhD Profile picture
19 Oct
I believe this week’s #COVID19 numbers will portend what’s in store for our nation later this fall winter. I believe we might have forestalled this had I been successful in persuading the POTUS and White House CoV Task Force to adopt my Oct 1 Plan, instead they denied deflected
Ideally we could have delayed the surge long enough maybe until Feb March as vaccines became available. Of course that assumes vaccines will be available by then and we don’t know that for sure
In any case looks like the train 🚂 is coming, not helped by a White House in denial, accelerating disinformation. It will be a rough fall and winter, advising to install now your social distancing team for next few months, look after mental health. Things will improve by spring
Read 5 tweets
Prof Peter Hotez MD PhD Profile picture
15 Oct
I found it meaningful to follow @LinaHidalgoTX tonight on @allinwithchris @chrislhayes we spoke on totally different topics: The Judge spoke about voting, I spoke about #COVID19 of course. But definitely #Houston TX was well represented tonight!
FYI I’ve had the opportunity to speak with @LinaHidalgoTX multiple times this year about #COVID19. And yes she really is that smart and committed. As is Mayor @SylvesterTurner, we’re blessed with strong smart leadership in H-Town, and genuinely kind compassionate people who care
In Texas we’re building for the future: Judge Hidalgo, born in Colombia 🇨🇴 29 yo brilliant @Stanford grad; Mayor Turner African American @Harvard_Law grad: diversity, brains 🧠, pragmatic leadership. My advice to young people: come to #Houston TX home of the real American dream
Read 4 tweets
Prof Peter Hotez MD PhD Profile picture
14 Oct
Promoting fake herd immunity concepts and other forms of weaponized science communication/disinformation will damage global public health, and maybe degenerate further into human rights violations. nytimes.com/live/2020/10/1…
We haven't seen too many examples of true herd immunity for #COVID19, possibly one of the first is in Manaus, Amazonas State #Brasil where it reached 66% medrxiv.org/content/10.110…
Extrapolating to the US: By invoking "herd immunity" we could easily increase our current 200,000 deaths by a factor X6 or more - 1 million deaths. Our vulnerable time is late fall 2020, winter 2021 = lame duck post election period. White House parting gift to the American people
Read 4 tweets
Prof Peter Hotez MD PhD Profile picture
3 Oct
Thread on POTUS therapies: Being asked about mab cocktail from Regeneron and remdesivir and what it means?

I think a key point is that use of antiviral drugs, if they are to be effective likely must be administered early in the course of the illness during viral replication.
"Watch and wait" not an option, if you are going to do it and maximize the effectiveness of these two interventions you pretty much either do it now or not at all. Later you may need to deal with host cytokine, inflammatory responses, in which case there are separate agents.
So I'm sure it was a tough call, but given what we know about coronaviruses, our work over the last 10 years shows how virus neutralizing antibodies are paramount in fighting the infection. Most vaccines work by this principle, including our SARS1, MERS, now COVID19 vaccines.
Read 9 tweets
Prof Peter Hotez MD PhD Profile picture
2 Oct
Wishing the best to POTUS and FLOTUS, given risk factors for the former, age and co-morbidities worth exploring Rx options
Possibly worth considering mabs Rx from @Regeneron investor.regeneron.com/news-releases/…
Or similar from @AbCelleraBio Lilly nih.gov/news-events/ne…
Read 7 tweets
Prof Peter Hotez MD PhD Profile picture
27 Sep
1/3 Thread:

Some of my talking points for this week (Sept 27-Oct 3):

1. Autumn-Winter surge may be starting now in the US, possibly we're already seeing this in upper Midwest, WI, ND, SD, IA
2/3 Thread:

2. The cold states may be especially susceptible this fall, reasons of "double indemnity" (idea from @PolicyLabCHOP):

People indoors more + Higher virus inoculum, virus does better in the cold...
3/3 Thread:

3. Take whichever vaccine you can as they become available in 2021. My reason: Priority to get some virus neutralizing antibodies into your system. Even if it's not the best vaccine, it's likely you can get boosted with better vaccines later in the year or in 2022.
Read 4 tweets

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