26./ PART 2 : Puberty Blocker Thread. @sjblakemore has shown the brain is radically transformed during the decade and more of adolescence with, for example, activity in the medial prefrontal cortex decreasing. In other words it takes time for our adult brain slowly to emerge.👇
27./ This is miles from the simple model of the Dutch protocol where adolescence is switched on and off like a tap. Our brains take time to change as our social skills fully reveal themselves. Switching off puberty risks disconnecting kids from their peers and social emotions.
28./ Just as adult body parts take years to grow so do our brain areas. Here's Blakemore again: white matter increases in the brain by just 1% a year during the whole of adolescence. But it doesn't do so as you might imagine by the brain just getting bigger.
29./ Instead the brain undergoes an amazing incremental process called myelination, the steady building up of white fatty matter (myelin) along the neural fibres that carry signals in our brains. It takes over a decade and reaches the decision taking parts of the brain last.
30./ The brain also undergoes wholesale 'synaptic pruning' where up to 50% of neural connections in some areas are lost. This may explain why adults tend to be less 'sensitive' or 'agitated'. We really don't feel many emotions as intensely (thank god:). ncbi.nlm.nih.gov/pmc/articles/P…
31./ What are the effects of puberty blockers on this reconstruction of the brain? No one really knows. There have been just a tiny number of studies into the impact of puberty blockers using brain scans and these have focused on 'executive function' or speed of reaction.
32./ So here we are: drugs created as an acceptable form of castration for adult cancer victims, that were used experimentally for unlicensed purposes on padeos are now being handed out to kids after zilcho cognitive research during their crucial period of cognitive development.
33./ This raises a question: are teens equipped to consent to taking these drugs, especially since their brains are in the throes of a revolution? We do know teens take many more risks and understand the consequences less than adults. nationalgeographic.com/magazine/2011/…
34./ Here's another question: non conforming teens often seek out a tribe of fellow LGBTQ+ peers. That's fine but we should be aware this is almost certain to affect their attitude to risk. Teens feel peer pressure viscerally and it really does make them take more risks.👇
35./ In Lawrence Steinberg & team's seminal experiment teens drive pretty safely in a video simulation...until they're made aware of the presence even in the next room of their mates. Disaster ensues as any parent of a teen might have guessed. ncbi.nlm.nih.gov/pmc/articles/P…
36./ fMRI brain scans show the reward circuitry of the teen brains lighting up. Teens feel a deep almost addictive need for the approval of their peers and it will make them take greater risks. Might this shed light on the impact of social media on girls transitioning?
37./ Who knows? What we do know is the result of animal studies and they raise concerns. When researchers gave young sheep puberty blockers males in particular became more agitated and emotional. gla.ac.uk/news/archiveof…
38./ You might think sheep ...bah, who cares...(sorry bad joke) but remember our friend Andrew V Schally who won the Nobel prize? He made his discoveries about GnRA by studying pig and lamb brains. The sheep researchers didn't stop there. They then designed an ingenious maze....
39./ With this they could test the ability of the sheep to remember their way through the maze to get the reward of food. Even after puberty blockers were stopped and obvious physical effects had 'reversed'...the memory of the sheep was impaired. sciencedirect.com/science/articl…
40./ What the researchers also found was that GnRA seeped into unlikely places and organs througout the young animals' bodies. The idea that GnRH is some discrete magic bullet that only switches off the growth of secondary sex characteristics is absurd.
41./ So does all this mean thousands of doctors, scientists and psychologists worldwide have colluded in a huge experiment on the bodies and brains of young people that's likely to end in exposure, legal cases and scandal? I don't know. But here's what I do know.
42./ Many years ago I worked on the first season of the BBC's 'Trust Me A Doctor' where @drphilhammond reported on the decision by the Royal College of Surgeons to publish data showing how each surgeon compared in terms of outcome. Many surgeons loathed it.
43./ The College was responding to an awful cover up at Bristol Royal Infirmary where over 100 babies had died unnecessarily in the cardiac department due to lax standards (over 20 were brain damaged). The inquiry concluded "children were not a priority". theguardian.com/uk/2001/jul/19…
44./ At a more trivial level one of my first docs for C4 was a show about laser eye surgery. We interspersed the science with a series of interviews with leading proponents of the miraculous wonders of laser eye surgery.....all of whom were wearing glasses. Err.....
45./ I'm a huge believer in modern medicine but doctors are a vested interest and sometimes they do the wrong thing. For example studies on the impact of anti-depressants on CHILDREN were wilfully misrepresented. Seroxat made kids MORE suicidal not less. theguardian.com/science/2015/s…
46./ The company who ran that trial and misreported the results was eventually fined $3Bn. I think I can guess why the manufacturers of GnRH analogues haven't published research of their own into puberty blockers in kids or tried to get them licensed for the purpose.
47./ Some bad science is seemingly well-intentioned. @jack_turban's paper on how puberty blockers supposedly save lives still gets quoted despite the fact the paper did NOT prove they saved lives; and may cause more suicide attempts. Here's my analysis 👇
48./ Over the years researchers have tried to estimate the damage that our medical infrastructure can unintentionally inflict on patients. The results are staggering. John Hopkins placed medical errors as the third biggest cause of death in the US. cnbc.com/2018/02/22/med…
49./ As for clinical trials they can be used not to find out the truth but as a way of drumming up interest among potential patients or doctors. I wonder sometimes if that isn't what happens with the "trials" of puberty blockers. Are they just marketing? theguardian.com/commentisfree/…
50./ If no child should be told they were born in the wrong body why should any child be told their bodies need changed or their brain's development smothered before it has barely begun? A reckoning on puberty blockers is surely on the way. It can't happen soon enough.

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More from @TwisterFilm

19 Oct
1./ I was just sent a video by @PeterTatchell celebrating 50 years since the Gay Liberation Front was founded. I hope you like my slight enhancement. How strange that in NONE of the archive is there a single appearance of those acronyms LGBT or LGBTQ. Wonder why? 👇
2./ You know for sure Peter would have chiselled them in if he could have found a single image. But just like the claim that trans people started the Stonewall riot the truth is trans people didn’t play a significant role in the founding of GLF. Nor did Peter.
3./ Peter didn’t arrive in the UK until the following year. The year before that a 19 year old women called @BevJacksonAuth became GLF spokesperson and told the Times, “we are not ashamed to be homosexual”. Almost exactly a year ago in 2019 she co-founded @ALLIANCELGB Image
Read 4 tweets
17 Oct
1./ Are children ever 'born in the wrong body'? A thread about schools, puberty blockers and children's brains. For years the idea of 'born in the wrong body' was a staple of trans activism. Now even Munroe Bergdorf has rushed to disown the phrase.👇 Image
2./By a TOTAL coincidence the UK govt recently decided to ban activists from schools who tell kids they could be 'born in the wrong body'. Here's Munroe saying she always knew her body wasn't right and it needed "adjusting". Isn't that just the same idea in different words?👇
3./ In this BBC video for primary schools 9 year olds are told "sometimes the feelings you have are the same as your body parts. And sometimes they're not". Isn't THIS just the same as 'wrong body'? If you're suspicious ...then you're right to be. 👇
Read 26 tweets
10 Oct
1./ Wakey wakey...gay boys. Did you sleep through the alarm? Did you decline those urgent calls from your lesbian sisters? Now it's YOUR turn to be gaslit as the trans project to destroy the very meaning of the word gay steps up a gear.👇attitude.co.uk/article/mr-gay…
2./ Look, I don't care who sleeps with or fancies any consenting adult. Good luck to them. But was it only me that missed the memo that said gay men can now have periods and...glory in how their "pussy bleeds". Yep, I'm betting you missed that memo too.👇 Image
3./ Before you turn over and go back to sleep maybe just think for a moment....if this person who is biologically female can now say they're a gay man who's just a "hairless small boy pumped with oestrogen" which female couldn't say the same?👇 Image
Read 8 tweets
9 Oct
1./ Boo hoo. A young gay bloke with the backing of the bloated ego that is @MrJohnNicolson couldn’t even convince the local SNP to make him a candidate never mind the electorate. Here’s why I’m relieved this particular gay man won’t be “taking the seat”.👇thenational.scot/news/18719186.…
2./ For one thing it’s not as if there’s a shortage of GAY MPs or MSPs. And here’s the thing: if say the awful Margaret Ferrier made a fuss about being straight you’d probably want less MPs that made a fuss about being straight. Ditto on the gay front.
3/. As a gay man I’m so weary of embarrassing or stupid GAY MPs who make a fuss about being gay while being total master debaters - or like Nicolson and @StewartMcDonald throw women under the trans express bus. It’s why I no longer think gay MPs deserve support just for being GAY
Read 8 tweets
22 Sep
😂 The Pink News comedy show keeps getting funnier. Here’s @benjamincohen responding to the govt’s announcement it has rejected gender Self-ID, which he championed for 5 years. He starts with a trademark bizarre accusation, this time about genital inspections. Click here to see👇 Image
2./ Then he tries to suck up to @trussliz claiming her rejection of Self-ID is....”sensible”. It is indeed which is why that’s been the central demand of @ALLIANCELGB since we were founded; despite furious accusations of “hatefulness” from Pink News and yep Benjamin himself.
3./ Here’s a reminder of just a few of the stories his demented rag has run demanding Self-ID in the last few months. The most recent was yesterday. 👇 In the world of Pink News no one just asks ....they plead. 🙏🏼🙏🏼🙏🏼🤦‍♂️ Image
Read 19 tweets
21 Sep
1./ If the UK govt really has rejected Gender Self-ID it will be a historic defeat for the "gender identity" lobby. But how did such a strange idea as Self-ID ever gain so much political traction? It's a bizarre and troubling story. thetimes.co.uk/article/changi…
2./ It all starts in Edinburgh in 1974 when two guys bring together gay organisations from across Europe to form the International Gay Congress. One of them, Ian Dunn, is an unrepentant paedophile and founder member of PIE. Here's his obituary.👇independent.co.uk/news/obituarie…
3./ IGC would go on to become ILGA, the pre-eminent international gay rights organisation; despite its status as a UN NGO being interrupted in 1994 when its links to pro-paedophile organisations were revealed. Here's ILGA's own take on that debacle.👇 ilga.org/ilga-ecosoc-st…
Read 25 tweets

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