Medical literature reports that every time the female pelvis is surgically invaded (think laparoscopy) adhesions are formed; evoking IBS. Symptoms of Endometriosis align with those of IBS. Endometriosis is simply a name chosen for a symptom constellation in search of a cause.
Even the Gynecology experts admit that cause of Endometriosis is unknown. Could a fomenting insult be widespread estrogen medication/overdose (BCP) of women since 1960’s? Now ~10% of women with Endometriosis! Unnatural!
Could Endometriosis be an iatrogenic disease; a mirage that evolves from Stage I to Stage IV via escalating laparosopic surgeries and repeated tissue ablations; exacerbated by applied unproven hormonal therapies?
UNEQUAL LEGS IN EDS: this is a subject that has titillated my clinical curiosity for many years. I have parked the idea here; so that I can pontificate on the subject over the next several days; as a threadreader chapter for my book.
SHORT LEG & CHRONIC PAIN
In 1972, I was building my first medical practice (San Francisco Bay Area) & heard about a seminar being put on by a famous British Orthopedic Medicine expert, Dr. James Cyriax. I went to his seminar & learned fundamentals of bio-mechanical diagnosis.
Over the years, Physical Therapists & Chiropractors have been reporting a phenomenon called the “Short Leg Sign”, which has been touted as a sign of lower body bio-mechanical disorder & pain generation.
DYSAUTONOMIAS of CARDIOVASCULAR SYSTEM are varied. MCAS & Vagus nerve function are mentioned, but authors chose to overlook common association of Panic Attacks, Mitral Valve Prolapse (MVP), & POTS with Hypermobility Syndrome.
Intriguing physiologic relationships between hypermobile tissues & cardiac dysautonomias? Hypermobility is an inherited tissue variation. Mitral valve & vascular tissues are comprised of connective tissue.
Loss of cardiac mitral valve competence & vascular tone likely potentiate hypotension & syncope. An expected homeostatic response to hypotension is hyperpneic lung efforts to gather more oxygen for blood, i.e., Panic Attacks.
MY RESPONSE: Landmark study or red herring? Study of 23 patients with Fibromyalgia (FM) & small fiber neuropathy(SFN; found in FM & diabetics) showed elevated HgbA1c levels & pain reduction with use of Metformin.
The authors point out the obvious: people with Fibromyalgia are often sedentary due to pain. Sedentary people ➡️ obese. Obesity ➡️ Diabetes, which ➡️ small fiber neuropathy.
ASSOCIATION OF hEDS & RHEUMATOLOGICAL DISORDERS; AN OPINION (1/7/2020):
Either there is genetic linkage between these disparate Syndromes or there is not. I searched for physiologic relationship, but I find no ready theories of associations between these diseases & tissue disorders.
The environmental dynamics that explain these relationships (associations) are sedentary lifestyles that beget weak bodies & chronic pain that forestalls ongoing pursuit of daily locomotor confrontations with the ambient gravitational field.
EDS: I include EDS in the estimated 15% of women I encounter in my medical practice and who have manifest hypermobility. My view is that Mother Nature gave women genes for ligaments rendered more lax, via the hormone Relaxin, to ease the bio-mechanical assaults of childbirth.
The genes for female Hypermobility are sex linked because men are not well served, in their pursuits of war & hunting, by delicate joints of knees, spine, & pelvis.
My encounters with the common expression of Hypermobility amongst Hmong, Mexican, & Hawaiian cultures, recently evolved from a long history of agrarian-subsistence existence, led me to a theory about why hypermobility genes are so highly conserved.
ARTHRITIS PREDICTS WEATHER? In previous posts (in my threadreader library) I have explained this phenomenon. The cause and effect is related to barometric pressure.
The body is like a sausage, with contained hard & soft tissues. Bones are connected by ligaments, which are highly imbued with pain fibers intended to keep us from injuring & stretching joint ligaments; to protect against being pulled asunder. Remember “Rack” of Inquisition fame.
When ligaments are lax from chronic wear, serial acute injuries, or from one serious joint injury, these injuries predispose joints to excessive range of joint motion & painful stretch of ligaments that tether these loose joints. Those with flexible joints potentiated for injury.