Thread by @BadgleyLaurence

DYSAUTONOMIAS of CARDIOVASCULAR SYSTEM are varied. MCAS & Vagus nerve function are mentioned, but authors chose to overlook common association of Panic Attacks, Mitral Valve Prolapse (MVP), & POTS with Hypermobility Syndrome.

https://twitter.com/BadgleyLaurence/status/1315600572301504512

Intriguing physiologic relationships between hypermobile tissues & cardiac dysautonomias? Hypermobility is an inherited tissue variation. Mitral valve & vascular tissues are comprised of connective tissue.

Loss of cardiac mitral valve competence & vascular tone likely potentiate hypotension & syncope. An expected homeostatic response to hypotension is hyperpneic lung efforts to gather more oxygen for blood, i.e., Panic Attacks.

Panic Attacks should be regarded as common dysautonomias, & which have pure physiologic etiology; rather then being summarily relegated to psychologic spheres & mental frailty.

Effect of gravity on vascular fluid column was recognized, but effect of gravity on vertical posture of those with Hypermobility Syndrome (HS) was not acknowledged. ‘Tis common for those with HS to have functional scoliosis when upright.

The assumption of a functional scoliosis when upright is likely the compensatory effort of the body to maintain a medial station of the body center of gravity.

Autonomic nervous system, both sympathetic & parasympathetic (Vagus), tracks bony spinal column. A curvilinear spine might evoke subtle degrees of jarring vertebrae subluxations & impingement of contiguous autonomic nerves.

Functional scoliosis magnifies when body tower is upright & neural impingement/dysfunction might more readily manifest in this body posture. Etiology of cardiac dysautonomias might be force of gravity acting upon hypermobile tissues.

The Study noted the evolution of cardiovascular atony after common episodes of sedentariness related to bedrest & convalescence from viral & other illnesses & injuries.

Atony of motor muscles would similarly afflict sedentary bodies; resulting in strained, spastic, & pained soft tissues when upright postures were subsequently undertaken.

All these physiologic dynamics might be the etiologic underpinnings for the Dysautonomias and Chronic Widespread Pain of the Fibromyalgia Syndrome.

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