This article raises some interesting points. Have death rates from COVID-19 gone done since March?

npr.org/sections/healt…
Now, I think it's reasonable to assume that the proportion of people who die after being infected by COVID-19 will fall over time. It's probably true that being infected today is less deadly than earlier this year
That being said, I'm quite skeptical of the evidence presented. This story seems to claim that death rates have dropped ENORMOUSLY, while I would expect something more in the range of a relative 10-20% drop (say from 25% to 20%)
The study that's linked to to verify the statement above is this one, and it's an interesting piece of research looking at some hospitals in NYC and the people they admitted for COVID-19 over time medrxiv.org/content/10.110…
Looking at the results table, something immediately springs out. The denominator here - the number of patients being admitted by week - has changed DRAMATICALLY over time
Perhaps more worryingly, that precipitous drop from 25% death rate to 7.6% cited in the news article appears to be based on...a single week of data. If you move back two weeks, there's no drop in death rates at all!
There also isn't really any trend here - a nonsignificant drop from 23% to 21% over two months, and then a sudden halving of the death rate in just one week, which corresponds to a sudden decrease in the average age
Moving on, we have the second paper cited in the NPR article, which looks at a very large sample of people who were admitted to ICU in English hospitals for COVID-19

medrxiv.org/content/10.110…
This study found that if you take the average death rate of these patients from the 'peak', it decreased in a linear fashion each week, and thus COVID-19 is getting less lethal
But why did they choose the 'peak' week? It wasn't the first week of data collection, and it's a bit arbitrary to only start counting from the worst week in the whole dataset
Indeed, if we extend the analysis back even just 3 weeks, the relationship disappears almost entirely and suddenly there's been very little difference since March!
I would go so far as to say that this study implies that any differences in ICU mortality in England due to COVID-19 are ~almost certainly~ down to admission criteria (which were strained during the peak in early April)
So, back to the question at the beginning of the thread: are your chances of dying from COVID-19 lower today than they were in March?

Honestly, while we'd hope so, I'm not sure we can conclude much either way

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More from @GidMK

22 Oct
Worth noting that this represents 607,559 COVID-19 tests with 226 positives, giving a positive rate of 0.0372%

Even if EVERY TEST was a false positive, that gives a specificity of ~99.96%
But, because positive people are almost always retested here we can actually examine this question more robustly. Of the 226 positive results, one was later retested and found to be a false positive! Image
To calculate test specificity, we take TN/(TN+FP) = 607333/(607333+1) = 99.99984%

To put it another way, very roughly 1 false positive test per million tests done
Read 5 tweets
21 Oct
Interesting new preprint on #LongCovid. Some take-homes:

- ~14% of people
- can last months
- associated with +symptoms, previous respiratory disease, gender, age
- not associated with metabolic disease (mostly)
medrxiv.org/content/10.110…
To me, this is the most interesting table. You can look through and see what is and isn't associated with PCR-positive Long COVID ImageImage
Not unsurprising that people who experience worse symptoms in their initial COVID-19 infection are more likely to suffer from #LongCovid
Read 8 tweets
20 Oct
Calling government action on COVID-19 "Health fascism" - a good start to what I'm sure will be a measured, balanced piece
Hm well I guess if the Human Rights Commission doesn't care about human rights during COVID-19 that would be a proble-oh, wait
Moving on we have...oh, some classic denialist tropes. That's not ideal

We're now numerically above the death toll of any pandemic since 1918, and the "survival rates" give your average 60 year old a 1 in 200 risk of dying
Read 5 tweets
19 Oct
Sweden is set to unveil a set of tough new regulations amid growing COVID-19 cases

businessinsider.com.au/sweden-shifts-…
Depressingly, there is little evidence that the pre-existing immunity from the first wave has substantially dampened viral spread, despite earlier hopes
Worth noting that Tegnell himself predicted that Sweden would reach "herd immunity" by mid-May originally, until serology studies proved that this was wrong
Read 4 tweets
18 Oct
People have been asking me to debunk this thread "proving" that COVID-19 deaths are false positives by correlating things, but instead I thought I'd simply list a few things that are more well correlated than this
US spending on science, and suicides by hanging/strangulation/suffocation

99.97%

"Biology just isn't like that"
Divorce in Maine, consumption of margarine

99.26%

"Biology just isn't like that"
Read 8 tweets
15 Oct
Something that I think is worth explaining:

The term "herd immunity" has a few different meanings, all of which are quite precise. This is an important point
In a very strict mathematical sense, herd immunity is the slowing of disease spread due to sufficient infected people in a population (such that Rt<1)
This leads to the second definition, which is the ability to calculate immunity within a population based on dynamics of disease spread
Read 9 tweets

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