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C. Michael Gibson MD

@CMichaelGibson

13 Nov

Many have become numb to pandemic statistics

Healthcare workers, though, must face the reality that there are now MORE PATIENTS HOSPITALIZED THAN AT ANY TIME in 2020, 40% more than 2 weeks ago

Some are working 36 hrs straight

The 3rd wave may break us

theatlantic.com/health/archive…

"They require twice as much attention as a typical intensive-care unit patient, for three times the normal length of stay. “It was doable over the summer, but now it’s just too much,”

“Last Monday we had 25 patients waiting in the emergency department. They had been admitted but there was no one to take care of them.” I asked her how much slack the system has left. “There is none,” she said.

Read 10 tweets

C. Michael Gibson MD

@CMichaelGibson

9 Nov

#Covid19 vaccine: Pfizer says drug more than 90% effective in preventing infection cnbc.com/2020/11/09/cov…

The analysis evaluated 94 confirmed Covid-19 infections among 43,538 participants.

The vaccine efficacy rate was above 90% at seven days after the second dose.

This is far above the 50% rate required by the FDA.

This is preliminary data.

The companies said they plan to submit the data to the FDA for emergency use authorization as soon as they have two months of data, which is currently on track for the third week of November.

Read 6 tweets

C. Michael Gibson MD

@CMichaelGibson

9 Sep

Breaking: Astra Zeneca halts vaccine trial for safety review due to a serious adverse event. Anonymous source ⁩says volunteer developed transverse myelitis, an inflammatory syndrome that affects the spinal cord and is often sparked by viral infection. nytimes.com/2020/09/08/wor…

The Duration of the safety review is unknown.

The Relationship of the case of transverse myelitis to the vaccine is unknown.

AZ’s vaccine uses a chimpanzee adenovirus to carry the #COVID19 genes into human cells. Although adenovirus are generally harmless,
they “can sometimes trigger their own immune responses, which could harm the patient without generating the intended form of protection.”

Read 6 tweets

C. Michael Gibson MD

@CMichaelGibson

16 Aug

#easylikeSundaymorning restoring this badly damaged 300 year old painting from the UK.

There are tears and holes in the canvas and missing paint.

Art restoration brings together my love of restoring things to vitality, painting, science and woodworking / cabinetry making.

I started by patching the tears & holes by using archival acid free glue to add new linen canvas to the back of the painting.

You can see how deep the holes are. Lots of layers of gesso, hide glue, & paint had been used 300 years ago. I have filled in the holes with Gesso, a kind of stretchable plaster. I added Lots of small layers until the gesso was just a little higher than the surface of painting

Read 20 tweets

C. Michael Gibson MD

@CMichaelGibson

27 Jul

I have questions:

1. The follow-up is 2 years after the 2cd dose in the Moderna trial. You cannot enroll if you plan to get another vaccine.

If I get randomized to placebo, & the drug gets approved, will the blind be broken at that time & will I be told I got placebo?

2. Is it ethical to have 15,000 people who were enrolled but received placebo, and don't know that they were randomized to inactive placebo in the context of this and other vaccines being approved?

If they knew, they could elect to get an active vaccine.

3. You could argue that the blind should be maintained to collect 2 year safety & effectiveness data. This is a valid argument to look at long term effects.
But the placebo patients are not being vaccinated, and there is an approved, effective vaccine available.
Is this fair?

Read 20 tweets

C. Michael Gibson MD

@CMichaelGibson

18 Jul

Text message from friend in California:

“Could you do a large abstract painting / splatter to match my horse and the colors in my living room”

Me: “It is 90 degrees out & perfect weather to do a splatter painting which allows the layers to dry quickly. I’ll start immediately!”

The first thing we need to do is cover up that sterile soul less white canvas.

Let’s quickly throw down some acrylic paint which dries really quick and allows us to lay down lots of layers ...

20 years of splatter / drip painting has taught me that the key to a good painting is knowing when to STOP ✋

It’s best to stop when you have the right balance of colors, size of drips, balance of shapes and a perfectly randomly random assembly of all the above.

Read 16 tweets

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