"They require twice as much attention as a typical intensive-care unit patient, for three times the normal length of stay. “It was doable over the summer, but now it’s just too much,”
“Last Monday we had 25 patients waiting in the emergency department. They had been admitted but there was no one to take care of them.” I asked her how much slack the system has left. “There is none,” she said.
The entire state of Iowa is now out of staffed beds. Worse is coming. Iowa is accumulating more than 3,600 confirmed cases every day; relative to its population, that’s more than twice the rate Arizona experienced during its summer peak, “when their system was near collapse,”
Smaller clinics, nursing homes, and long-term-care facilities are still struggling to provide personal protective equipment, including gloves and masks. “About a third are completely out of at least one type of PPE”
"They’ll have several tubes going into their heart and blood vessels, administering eight to 12 drugs—sedatives, pain medications, blood thinners, antibiotics, and more. All of these must be carefully adjusted, sometimes minute to minute, by an ICU nurse just to keep them alive,”
"No one has reinforcements to send. There are travel nurses who aren’t tied to specific health systems, but the hardest-hit rural hospitals are struggling to attract them away from wealthier, urban centers. “people don’t want to work in Fargo, North Dakota, for the holidays,”
"nurses who are positive for COVID-19 but symptom-free can return to work in COVID-19 units. “That’s just a big red flag of just how serious it is,” Suttle says. (The North Dakota Nurses Association has rejected the policy.)"
“to protect yourself, you just shut down. You get to the point when you realize that you’ve become a machine. There’s only so many bags you can zip.”
"As the pandemic moved out of big cities & into rural towns, health-care workers were more likely to treat people they knew personally—relatives, hospital colleagues, the bus driver who drove their kids to school. The lines between our personal lives and our careers are gone,”
"After SARS hit Toronto in 2003, health-care workers at hospitals that treated SARS patients showed higher levels of burnout & PTSD up to two years later, compared with those at hospitals in nearby cities that didn’t see the disease. That outbreak lasted just four months."
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The analysis evaluated 94 confirmed Covid-19 infections among 43,538 participants.
The vaccine efficacy rate was above 90% at seven days after the second dose.
This is far above the 50% rate required by the FDA.
This is preliminary data.
The companies said they plan to submit the data to the FDA for emergency use authorization as soon as they have two months of data, which is currently on track for the third week of November.
Breaking: Astra Zeneca halts vaccine trial for safety review due to a serious adverse event. Anonymous source says volunteer developed transverse myelitis, an inflammatory syndrome that affects the spinal cord and is often sparked by viral infection. nytimes.com/2020/09/08/wor…
The Duration of the safety review is unknown.
The Relationship of the case of transverse myelitis to the vaccine is unknown.
AZ’s vaccine uses a chimpanzee adenovirus to carry the #COVID19 genes into human cells. Although adenovirus are generally harmless,
they “can sometimes trigger their own immune responses, which could harm the patient without generating the intended form of protection.”
There are tears and holes in the canvas and missing paint.
Art restoration brings together my love of restoring things to vitality, painting, science and woodworking / cabinetry making.
I started by patching the tears & holes by using archival acid free glue to add new linen canvas to the back of the painting.
You can see how deep the holes are. Lots of layers of gesso, hide glue, & paint had been used 300 years ago. I have filled in the holes with Gesso, a kind of stretchable plaster. I added Lots of small layers until the gesso was just a little higher than the surface of painting
1. The follow-up is 2 years after the 2cd dose in the Moderna trial. You cannot enroll if you plan to get another vaccine.
If I get randomized to placebo, & the drug gets approved, will the blind be broken at that time & will I be told I got placebo?
2. Is it ethical to have 15,000 people who were enrolled but received placebo, and don't know that they were randomized to inactive placebo in the context of this and other vaccines being approved?
If they knew, they could elect to get an active vaccine.
3. You could argue that the blind should be maintained to collect 2 year safety & effectiveness data. This is a valid argument to look at long term effects.
But the placebo patients are not being vaccinated, and there is an approved, effective vaccine available.
Is this fair?
“Could you do a large abstract painting / splatter to match my horse and the colors in my living room”
Me: “It is 90 degrees out & perfect weather to do a splatter painting which allows the layers to dry quickly. I’ll start immediately!”
The first thing we need to do is cover up that sterile soul less white canvas.
Let’s quickly throw down some acrylic paint which dries really quick and allows us to lay down lots of layers ...
20 years of splatter / drip painting has taught me that the key to a good painting is knowing when to STOP ✋
It’s best to stop when you have the right balance of colors, size of drips, balance of shapes and a perfectly randomly random assembly of all the above.