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20 Nov, 4 tweets, 4 min read
Today the @WHO rejects Remdesivir for #COVID19.
The same drug the @US_FDA gave a full approval.
Because the @WHO reviewed all the data and made the right call.
bmj.com/content/bmj/37…
@bmj_latest
The @nytimes coverage
nytimes.com/2020/11/19/hea…
The scandal, uncovered @ScienceMagazine
The timeline of Gilead negotiation with EU and the FDA approval, vis-à-vis knowing the SOLIDARITY (@WHO) trial results

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More from @EricTopol

Eric Topol Profile picture
18 Nov
It was "incalculable" on May 24th.
The loss of 250, 000 Americans as of Nov 18th is indescribable. Unfathomable. And mostly preventable.
"They Were Not Simply Names on a List"
"They Were Us"
Each American lost an average of 10 years of life and left behind an average of 9 family members grieving. Still grieving their loss, 6 months later.
Now multiply that 2.5 times.
Our family, friends, patients, coworkers, neighbors, our fellow Americans. Lost souls.
Today we had the highest number of deaths since early May @COVID19Tracking
Read 4 tweets
Eric Topol Profile picture
18 Nov
The @Pfizer/@BioNTech_Group vaccine trial is complete for efficacy. Of 43,661 participants, 170 events, 162 in placebo group, 8 in the vaccine. That's 95% efficacy; *phenomenal*; replicated @moderna_tx, ~ as good as it gets👇
statnews.com/2020/11/18/pfi… @damiangarde @matthewherper
The only silver lining of rampant covid spread in the US is that the vaccine trials are getting completed much faster
Good timing for this FAQ today @washingtonpost washingtonpost.com/health/2020/11… by @Carolynyjohnson @asteckelberg @PostGraphics
Short answer: They work really well
We'll see all the data, w/ safety, very soon at external advisory mtg
Infographic: where we go from here, important stuff
Read 4 tweets
Eric Topol Profile picture
18 Nov
This is great news tonight--the first--and hopefully a @US_FDA precedent for may more rapid (<30 mins) home covid tests
@LuciraHealth
FDA EUA letter fda.gov/media/143810/d…
Coverage on this @nytimes @KatherineJWu nytimes.com/live/2020/11/1…
My post from July on this. It has taken waaaaay too long but we're getting there. RT-LAMP today, antigen tests to come.
Without prescription, cheap, every household, ASAP
Read 4 tweets
Eric Topol Profile picture
18 Nov
Yes, America, there is a state with a 62.9% test positivity, the 3rd highest new cases per capita in the world, and a rapidly rising death rate
This section of the country (started w/ the Dakotas), is spreading in every direction. Minnesota now going vertical. Grossly inadequate testing w/ positivity now:
South Dakota 57.5%
Iowa 51.7%
Idaho 42.0%
Kansas 40.9%
Montana 24.6%
covidexitstrategy.org
Brilliant.
Read 5 tweets
Eric Topol Profile picture
18 Nov
At a time when 22% of US hospitals have insufficient #healthcare frontline work force
theatlantic.com/science/archiv…
It couldn't be a worse time for setting new records every day for covid hospitalizations. Today > 75,000, rising quickly.
@COVID19Tracking
76, 830 hospitalizations
1,565 deaths
In the span of just 7 days, there's been a 25% increase in hospitalizations, the worst increase we've seen to date Image
Read 5 tweets
Eric Topol Profile picture
16 Nov
Very exciting to see 94% efficacy of @moderna_tx #SARSCoV2 vaccine at interim analysis of 95 events. This replication of Pfizer's high efficacy tells us the virus is eminently vaccinatable. investors.modernatx.com/news-releases/…
Before year's end we will have at least 2 vaccines with EUAs to proceed with Phase 1a rollout, a historic science achievement in < 12 months. For context:
The replication is independent. A separate Data & Safety monitoring board of Operation Warp Speed did the review. Yes, it's another mRNA vaccine, but it's the same target, the spike protein, shared by the other Phase 3 vaccine programs. They should all work well. We need them too
Read 5 tweets

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