📝VACCINE MIGHT BE BETTER than natural #COVID19 recovery for immunity. 36 days after 2nd dose of vaccine, titers for binding & neutralization are often substantially better in vaccinated individuals than naturally recovered patients (labeled as "convalescent"). 
https://twitter.com/trvrb/status/1328584228070690817
2) The above figure from the original Phase 1 trials of the Moderna vaccine. Hence why you should try to rely on the vaccine instead of natural infection (ie don’t do natural plow thru herd strategy). nejm.org/doi/full/10.10…
3) What about the Pfizer / Bio-N-tech vaccine—do we see the same pattern?? YES! Notice how antibody binding and neutralizing titer again higher for the Pfizer vaccine than natural #COVID19 infection recovery (labeled HCS). nejm.org/doi/full/10.10…
4) That said, Harvard immunologist Michael Mina is slightly unsure if the initial >90% efficacy of the vaccine will hold forever long term because immunity response is often stronger early on but plasmablasts can wane.
https://twitter.com/michaelmina_lab/status/1328355643300917249
5) Thus, we must be careful not to assume the efficacy is 90% or more — it might persist but it might drop over time. This is why we need to full trials. Let’s be optimistic but fingers crossed 🤞🏼 on 90-95% efficacy holding.
https://twitter.com/michaelmina_lab/status/1328356167031074818
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