1/ Here’s this week’s @Nutrita_app #science email. Sign up for them at nutrita.app

“You’ve heard it before, fat will make you fat. It’s calorie dense and tasty. End of story.

Wrong. Although fat is calorie dense and fat is tasty, it doesn’t make you fat per se.
2/ “It’s not enough - overfeeding studies make this crystal clear [pubmed.ncbi.nlm.nih.gov/7369169/ & pubmed.ncbi.nlm.nih.gov/1414963/]. However, it’s true that some fats are more fattening than others (on a per calorie basis). See our Good fats, Bad fats article for more nutrita.app/good-fats-vs-b…
3/ “Linoleic acid (LA), the major omega-6 fat in the modern diet, is the most fattening fat [ncbi.nlm.nih.gov/pmc/articles/P…]. Its flexible and delicate polyunsaturated nature is to blame. More saturated fats - rigid and robust - like the monounsaturated oleic acid or the totally
4/ “saturated palmitic acid, aren’t fattening. Or less fattening, if you prefer.

In the modern diet, LA is mostly obtained from high omega-6 seed oils like sunflower, corn, wheat and soybean oil. In comparison, whole nuts, seeds and animal sourced foods are minor contributors.
5/ “Eliminating high omega-6 seed oils from your diet is key to fat loss. Arguably, it’s just as or more important than cutting out sugar and flour.

Nutrita’s nutrient density score penalizes foods with a high LA content nutrita.app/keto-score/.
6/ “No other app factors that into their food scores.

As I see it, there are two ways to get fat. You can either produce way too much insulin by eating sugar and flour or you can increase your fat cell’s sensitivity to insulin by eating lots of LA. Deep-fried foods combine both!
7/ “The magic of Nutrita’s approach is that both fat-loss levers are pulled by removing sugar/flour and LA: less insulin is knocking on your fat cell’s front door offering energy to store AND you’re better able to resist its calls.
8/ “Once fat cells aren’t overloaded they do their job of expertly, metering out stored fat for moment-to-moment energy needs. You get stable energy levels, snacking is less compulsive and your hunger is normalized.

What’s not to love?
10/ “Remember to subscribe to our YouTube channel [youtube.com/channel/UCECVh…] & join our Facebook community [facebook.com/groups/nutrita…]. We’re putting up lots of new videos showing you how to use the app to solve common issues like meeting your protein target

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More from @raphaels7

27 Nov
1/ Here’s the 3-week *retrospective* RCT mentioned by @foundmyfitness & Dr.Fahey

females drank 600μmol glucoraphanin (GR) + 40μmol sulforaphane (SF) daily, showing no goitrogenic effects or immune responses against it - contrary to what @CarnivoreMD claims

lets jump in Image
2/ in other of Dr.Fahey’s papers he averages GR’s bioavailability to 10%, so lets go with that: 40 SF + (600 GR x 0.1) = 100μmol SF in the drink

100μmol SF/daily didn’t interfere with the thyroid in 26 women (TSH, fT4, TG TPO- & TG-antibodies), 45 if you add placebo group
3/ they were 7yrs older (48 vs 41) & had a 0.8 higher TSH (4.6 vs 3.8, but neither of these differences seems to matter. these women didn’t see goitrogenic activity because too little SF made it to the tissue, not because SF isn’t a goitrogen

the dose makes the poison Image
Read 11 tweets
27 Nov
1/

Fuck me

1.88M views for "A Mom Tried Keto Diet For 30 Days. This Is What Happened When Things Went Wrong"

"Based on the comments, an incredible amount of people missed what actually happened here...
2/ "She had a tumor in her pancreas that caused a chronically elevated level of insulin, which was constantly pushing her blood sugar below the normal range. Going keto forced her body to rely entirely on the glucose it produces itself, which your body is normally able to do..."
3/ "without problems, especially after it has adapted to using ketones for fuel for most things. Due to the chronic hyperinsulinemia, her body was not able to function normally. Going keto actually revealed an underlying medical condition that otherwise might have gone unnoticed"
Read 4 tweets
8 Jun
2/ the in vitro study does indeed show, as you say, that LA strongly inhibits viral replication and thus strongly drops viral load. the caveat being that this occurs at non-physiological levels that are x2-5 higher than plasma values (per my back of the envelope estimation)
3/ the n3 rat study shows that high-dose fish oil dampened inflammation too much, increasing mortality. this is analogous to when people take too much anti-inflammatories for pain, but eventually end up with paradoxically worse pain (possibly due to interference with resolvins?)
Read 8 tweets

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