Thread by @purviparwani

Doing this as PSA!
Those who are worried about side effects of the vaccine- here is the @NEJM paper on #Pfizer #Covid vaccine!

nejm.org/doi/10.1056/NE…

@DBelardoMD @mirvatalasnag @onco_cardiology @AChoiHeart @SaynaNorouzi @DrAsifQasim @datsunian @aayshacader @PushpaShivaram

💉 two 30-μg doses of vaccine, administered intramuscularly 21 days apart!
💉 Adverse event data through approximately 14 weeks after the second dose are included in the paper. Collected upto 6 months after the vaccine!

💉 side effect of general reactogenicity mainly headache/ fatigue/ fever —less common and milder in older adults than in younger adults.
💉 These side effects were more common and severe after the 2nd dose than after the 1st one.
Severe fatigue was observed in approximately 4%

💉 Overall, side effects were transient and resolved within a couple of days after onset.
💉 Lymphadenopathy( swollen lymph nodes) resolved within 10 days, probably from vaccine-elicited immune response.

Most importantly—
95% efficacy!

Trial was not designed to tell us how effective the vaccine was after first dose only but , in the interval between the first and second doses, the observed vaccine efficacy against Covid-19 was 52%, and in the first 7 days after dose 2, it was 91%,

After 7 days of second dose— patients were at the best vaccine efficacy to fight against the virus. Which will mean after taking the vaccine one has to wait almost a month to get 95% against the virus! Not bad at all!

I cannot wait to get it! #HCW4vaccine #VaccinesWork