Share this page!

Eric Topol Profile picture
Twitter logo
26 Dec, 4 tweets, 2 min read
Countries the B.1.1.7 variant has been found in:
UK, Denmark, Singapore, Australia, Netherlands, Sweden, Spain, Switzerland, Lebanon, France, Israel, Italy.
Hard to imagine it has not reached US by this time
Add: Japan, Iceland, Belgium, Germany
Now add Ontario, Canada in a couple with no history of travel
Add Hong Kong, Ireland, Sweden
@MOUGK

@firefoxx66
(with separate introductions Hong Kong, Australia)

• • •

Missing some Tweet in this thread? You can try to force a refresh
　

Keep Current with Eric Topol

Eric Topol Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @EricTopol

Eric Topol Profile picture
24 Dec
We've now doubled the peak hospitalizations from the previous 2 US case surges.
And it's no wonder the death toll again today is nearly 3,500.
@COVID19Tracking
Sure the virus is hard to contain, but that's especially the case when so little is being done
The @HHSgov declared covid as a public health emergency on Jan 31st
And @WhiteHouse a national emergency March 13th whitehouse.gov/presidential-a…
If that was emergency, then what is this?
The actions we could take beyond financial support that still has not been approved......
1. Distribute high quality (surgical or K/N95) masks to all households [@USPS planned 650 million distribution in April, blocked by @WhiteHouse]
2. Make mask mandates a national policy with enforcement
3. Provide free rapid home covid tests to all households for daily use
Read 5 tweets
Eric Topol Profile picture
23 Dec
1. Structural biology has been a standout in the pandemic, mapping the virus, antibodies and vaccines atom by atom. So I had a conversation with one of its leaders, Andrew Ward @WardLab1, my @scrippsresearch colleague soundcloud.com/prescrippsions…
2. Back in 2016, Andrew and his colleagues were the first to see and publish the coronavirus spike protein, via cryo-electron microscopy (a common cold virus, HKU1) nature.com/articles/natur… @nature
Note the team, which proved to be formidable
@McLellan_Lab @KizzyPhD Barney Graham
3. In the podcast, Andrew reviews how they came together. A next act was the famous 2P (2 proline substitutions) paper that was rejected 5 times before being published @PNASNews
Subthread about that here:
Read 14 tweets
Eric Topol Profile picture
21 Dec
The B.1.1.7 variant has 23 mutations
I spoke to Andrew Ward (@WardLab1) @ScrippsResearch today (podcast coming) about its structural biology. He thinks the N501Y (in common w/ South Africa variant) is the driver for increased transmission; he's not concerned re: vaccine efficacy
On @CNN @wolfblitzer, @NYGovCuomo just said the new variant transmits 70-fold the D614G and that it accounted for Europe’s 2nd wave. Both are wrong!
While the B.1.1.7 variant is thought to have been derived from accelerated evolution in an immunocompromised patient with covid (see examples in these 2 @NEJM reports), if the functional culprit is indeed N501Y, that might turn out to be a red herring
Read 4 tweets
Eric Topol Profile picture
18 Dec
1. There are limited data about the vaccines for people who have had covid. But we can learn from the @Pfizer @BioNTech and @moderna trials which had 3% and 2.2% participants respectively confirmed at baseline (via FDA briefing docs)
2. In the Pfizer trial there were 9 reinfections among 670 participants (1.3%) who received placebo which was the same rate as those without prior infection (259 of 19,818 participants, 1.3%).
Only 1 reinfection in the vaccine group (after ≥ 7 days) for those w/ prior infection
3. We need to learn more about this with so many people with prior infections getting vaccinated. But this finding suggests vaccine-induced immune response may add protection to the natural response and adds another layer to the superhuman concept 👇
Read 4 tweets
Eric Topol Profile picture
18 Dec
How do you get to over 240,000 covid cases in one day?
Ask the USA.
An unabated virus.
A rudderless country.
Today @COVID19Tracking
With more than 114,000 Americans hospitalized
Our status in San Diego and LA.
Hope yours is better
Read 4 tweets
Eric Topol Profile picture
17 Dec
You have one guess for what is @ScienceMagazine's Breakthrough of the Year, 2020 😉
The new issue is full of insightful, useful content on the pandemic
This "Year like No Other" timeline is the best I've seen so far
@ScienceVisuals
science.sciencemag.org/content/370/65…
science.sciencemag.org/content/370/65…
Vaccines. The hope. @sciencecohen reviews the vaccine landscape, the 95% efficacy in context, and gets personal about his mother
Read 5 tweets

Did Thread Reader help you today?

Support us! We are indie developers!

This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!

Follow Us on Twitter!

Like this author's thread?

Get emails when @EricTopol has new unrolls!

Check out other threads from @EricTopol!

Read all threads by @EricTopol