Who is in intensive care and where are they? A thread.

The Intensive Care National Audit & Research Centre @ICNARC have just published their report on COVID-19 patients admitted to ICU/HDU in England, Wales, and Northern Ireland.

icnarc.org/Our-Audit/Audi…
It looks at two periods: up to 31 August (including the devastating first wave), and 1 September - 30 December. There is a lag in reporting, so not all patients are recorded in the Sep-Dec figures.

Remember, these are patients that are *very ill* requring intensive care.
Wide distribution of patients across the country.
This is the picture of admissions to intensive care in the past 14 days (2 weeks).

From 1 Sep - 30 Dec, there are around 17 weeks.

So if things were the same we would expect 2 / 17 = 12% in the last 14 days.

In London, 716/1933 (*37%*) patients admitted in the past 2 weeks.
In the South East, 333/1018 = 33%
E. England, 285/861 = 33%

Wales 88/440 = 20%

South West, 71/414 = 17%
Midlands, 286/1809 = 16%
N. Ireland 24/212 = 11%

NE & Yorkshire, 173/1696 = 10%
North West, 168 / 1766 = 10%
The orange lines show the trajectories in each region (compared to the blue line for the start of the epidemic).

London / South East / East of England showing exponential-type growth
The problem with ICU patients is that they stay in hospital for a long time. So there is a cumulative effect - it's not just admissions, it's how many people *remain* in ICU. These aren't patients who are in for the day. They accumulate increasing pressure on ICUs.
Here are the ICU patients *in hospital* for each region.

*All regions* are increasing.
In April, we had many ICU admissions but *very few* non-COVID ICU patients. Now we have many more. This increases pressure on ICUs. Note December data yet to come in this chart.
And who are these patients?
This is how old they are. You can look at average age (the mean) or the middle person's age when lined up from youngest to oldest (the median). Either of these is around 60 years old.

You can also look at what is called the inter-quartile range (IQR)...
That shows that 25% of ICU admissions are *52 or younger*.

This is not just a disease of older people.

Remember, these are very ill patients in critical/intensive care. Many patients will die.
It also does not affect people equally. We can look at admissions to ICU by deprivation.

If a 'fair' disease, we would expect 20% of ICU admissions to be in each IMD group (1-5).

Instead, we see 31% in the most deprived group and 12% in the least deprived group.
It also disproportionately affects men. Two thirds of ICU admissions are males.
And the vast majority were living unaided before COVID.

87% living without any assistance.

They are now in intensive care.
Over 10% of 16-49 year old women admitted to ICU are or had recently been pregnant.
Around one third of ICU admissions sadly died.
This is a dire situation. The Government needs to introduce more stringent measures to prevent this becoming even worse.

Schools should remain closed until we have this situation under control, R is reduced to below 1, and we have regained capacity in hospitals.
For those wanting to keep track of the epidemic in the UK, I produce heatmaps of detected cases, positivity, hospitalizations, and ICU admissions each Thursday. I pin these tweets to my profile. Here is the latest. Follow me to get the latest versions.

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More from @Dr_D_Robertson

3 Jan
Case rates now and 3 months ago when SAGE suggested a 'circuit breaker' news.sky.com/story/coronavi…

Data from coronavirus.data.gov.uk

A short thread. ImageImage
22 September: the day after the SAGE meeting.

6,300 cases (7 day average)
354 patients admitted to hospital (7 day average)
1,634 patients in hospital (7 day average)
204 patients in mechanical ventilation beds (7 day ave)
34 deaths/day (7 day ave, within 28 days of +ve test) Image
20 October

21,866 cases
1,251 patients admitted to hospital
8,499 patients in hospital
733 ventilated patients
217 deaths/day Image
Read 7 tweets
31 Dec 20
Here are the heatmaps for Covid detected cases, positivity, hospitalizations, and ICU admissions. This is up to week 52 (21-29 December). This covers Christmas, so data should be interpreted with caution.

And some commentary in the thread of where we are at the end of 2020.
Detected case rates. Very high amongst working age population, highest in 30-39 year olds. Rates above 150 cases per 100,000 (ie very high rates) in *all* age groups (colour and monochrome versions below)
However, not all cases are detected, so we can look at positivity (number of people testing positive / number of people being tested).

Over 10% positivity in under-80-year-old males and in under-50-year old females.

For the first time, there is over-10% positivity in children.
Read 19 tweets
3 Dec 20
Mass testing. Results from the Liverpool trial. A thread. And a big problem.

gov.uk/government/pub…
A bit of background. To get out of national Lockdown 1, we were promised a test trace and isolate system. That uses PCR tests. These are accurate, but take time to get results back. There were also significant issues in the way that the Government organized 'NHS' Test & Trace
The Government is now relying on a less accurate technology, Lateral Flow tests. In order to roll these out nationally, the Government tested these.
Read 13 tweets
2 Dec 20
MHRA / JCVI Briefing live
First phase JCVI prioritization overview Image
First phase prioritization. Only difference is confirmation of 16 as minimum age for recieving the vaccine (for phase 1 only higher risk younger people) Image
Read 7 tweets
26 Nov 20
Here is the justification document for which regions were placed into each tier from 2 December.

A walkthrough thread.

assets.publishing.service.gov.uk/government/upl…
This updates the Government's prior systems, documented here:
Here's the summary chart.
Read 24 tweets
26 Nov 20
As soon as we come out of lockdown, we will have one million students moving around the country returning home. Some of these will be infected and will go on to spread the virus. Here's the latest data from PHE showing transmission last week in lockdown

We also have a significant issue when schools break up. These are the latest data for outbreaks in schools

Schools break up around 19 December. What happens if children are infected on the last day of term?
Read 5 tweets

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