.@NYGovCuomo : "If the UK spread catches on in NY, hospitalization rate goes up, hospital staff gets sick - then we have a real problem. Then we're at shutdown again."

The problem with capacity now is staff shortage, he says. "We have beds, we have equipment." Primarily nurses.
Cuomo: Very worried about UK strain. Still just 1 case confirmed in NY, but believe we have more. Notes spread in UK only took about 3 weeks.

Says this concern + staff shortages at hospitals is why such a push for faster vaccination of health-care workers.
Cuomo: "We have seen a dramatic increase" in performance of vaccinations.

Were doing 10k per day for first several wks

On Monday, went to 30k

Tuesday, a little over 30k

Wednesday, went to 50k

And today going to be in excess of 50k

"That's 5 times the rate they were doing."
Cuomo: Refusal rate varies. Drs taking vaccine at much higher rate. Anecdotal, but would expect to see numbers around 80% for drs. "And drs know best."

Nurses, there's a variation. Would expect to see that 70-80%. 70 is the minimum threshold for viability of vaccination program.
Cuomo: 2M health-care workers in state. Only have 900k doses for the 2M.

"Any hospital that hits their refusal rate, fine, tell me, we'll reallocate it - bc overall we don't have enough dosages for half the population of health-care workers."
Cuomo: After 1a we'll go to 1b - frontline essential workers & aged 75+.

1b is over 3M people.

We're getting 300K doses per week.

"The supply is our issue."
Cuomo: 1b distribution mechanism different - going to use thousands of points of distribution across the state - pharmacies, drs offices, FQHCs, community groups.

Firefighters, police, teachers, transit workers in 1b. Many have health workers - aim is for them to self-administer
(Self-administer, meaning for eg having firefighters' EMS workers administer the shots. Not actually giving themselves their own vaccines.)
Cuomo: When priority 1b vaccinations start, no local govt can prioritize any group over another, ie police over teachers over those age 75+. "That just will not be allowed, period." Everyone in the priority group gets access.
Cuomo: 75+ group in NY is 1.3M people. Distribution mechanism will be pharmacies, dr networks, local health dept operations, community groups - public housing, churches, etc.
Cuomo: "If by the end of next week we did nursing home residents and staff, that would be a great accomplishment. Then health-care workers so we have hospitals working. Then 1b is going to be very large, but distribution network will be large." But supply so far behind dist.

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More from @megtirrell

6 Jan
J&J’s CEO, Alex Gorsky, on events in Washington: Image
.@steveubl of @PhRMA on events in Washington: Image
Pfizer CEO @AlbertBourla letter to employees on events in Washington: Image
Read 4 tweets
6 Jan
"Certainly it's had a rocky beginning," @NIHDirector tells @washingtonpost Live of #covid19 vaccine rollout. "Maybe we shouldn't be too shocked that it didn't go like clockwork," but says "things are starting to pick up." Says 1M injections per day "is good benchmark to reach."
Collins declines to make a specific estimate for herd immunity, but says "let's go for 80-85%; that ought to be sufficient for achieving herd immunity."

"Talking in the neighborhood of 300M... getting immunized in the coming months."

(How do we do that w/o vaccinating kids?)
"There's a pretty clear path for getting where we need to be by summer," @NIHDirector tells #postlive of #covid19 vaccine rollout. Says processes are falling into place.
Read 5 tweets
20 Dec 20
CDC’s #ACIP just now reiterates OWS projections for #covid19 vaccine supply:

By end of Dec: enough for 20M people
End of Jan: enough for 30M more people
End of Feb: enough for 50M more people

(2 doses each)

We know Dec supply will stretch into 1st wk of Jan for administration
CDC’s #ACIP has not yet voted, but recs for groups next in line for #covid19 vaccines are people 75+ and frontline essential workers, including:
Firefighters, police
Teachers, support staff, daycare
Food & agriculture
Manufacturing
Corrections
Postal, public transit
Grocery store Image
CDC #ACIP’s considerations for next groups + how many in each for #covid19 vaccine prioritization (vote this afternoon):
Phase1a: healthcare workers, nursing home residents (24M)
1b: Frontline essential workers, 75+ (49M)
1c: 65-74, high-risk, other essential workers (129M) Image
Read 6 tweets
7 Dec 20
.@NYGovCuomo asks Dr Fauci: When is 75-80% of population being vaccinated feasible?

Dr Fauci: Going to be entirely dependent on how well we do - how I do, you do - on getting message out about how important it is for people to get vaccinated. (1)
Dr Fauci to Cuomo on #covid19 vaccination timeline:

-By end of Dec, substantial proportion of health-care providers and people in nursing homes will be vaccinated

-By the time you get to beginning of April, you'll start to get people who have no high priority (2)
Dr Fauci: "In a full-court press," through April, May and June, by the time you get to the summer (w prime-boost doses & 7-10 days for immunity), by the "core of summer, end of summer, start of third quarter of 2021, we should be in good shape. That's what I'm hoping for." (3)
Read 4 tweets
3 Dec 20
This appears to be an explainer of a change that happened in Pfizer's #covid19 vaccine supply expectations between Sept. 9 and Nov. 9, which flew under the radar because Pfizer reduced the 2020 supply expectation in the same release it reported 90% efficacy for the vaccine (1)
In Aug & Sept, Pfizer was forecasting up to 100m doses of its #covid19 vaccine by the end of 2020, and up to 1.3B doses by the end of 2021: (2) Image
Nov 9, when Pfizer reported its first phase 3 efficacy data, it included the new (reduced) forecast for supply: (Link here bc the dateline isn’t visible in this photo: pfizer.com/news/press-rel…) (3) Image
Read 6 tweets
5 Oct 20
.@HallieJackson says Regeneron Chief Scientific Officer Dr George Yancopoulos coming up next with her on @MSNBC
@HallieJackson asks: What do you know about these 3 drugs together?

GDY: Our antibody cocktail essentially just mimics the normal immune system... theoretically there should not be any additional interactions with these other medications than you'd have with your own antibodies.
Yancopoulos also notes that bc Regeneron's antibody cocktail boosts the immune response, the concern about giving immunosuppressive dexamethasone earlier in course of disease may be lessened.
Read 4 tweets

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