#DDDD

I think the fact that MRx0518 is showing massive near term promise in cancer, yet 4D continue to focus on Parkinson's Disease shows me how excited and effective they believe MRx0029 may be for Parkinson's
(Market expected to reach $8.3bn by 2026)

medgadget.com/2020/02/parkin… Image
#DDDD $LBPS

After discussing MRx0029 in the text, the author from 4D heavily alludes to bringing in a partner... Image
#DDDD $LBPS

BOLD Statement

'MRx0029 has shown promise as a potentially
disease-modifying therapy, by indicating a potentially neuro-regenerative effect' Image
#DDDD

'We are in the process of evaluating designs for a potential first-in-human clinical trial of MRx0029 in patients with PD and have enlisted the help of key opinion leaders in PD clinical study design to assist in planning' Image
#DDDD

'MRx0002 was able to COMPLETELY PREVENT the onset of disease in an acute experimental autoimmune encephalomyelitis (EAE) animal model of MS, and histological analysis in these models showed significantly reduced inflammation of the spinal cord' Image
#DDDD

'MRx0002 completely prec(V?)ented the onset of disease, and had very strong efficacy as determined by clinical scoring' Image

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More from @AimHardy

11 Jan
Thread

Life expectancy over a 300 year time span

1800 to 2100

(IMO I believe millennials who looks after themself now will now live beyond 150 years old due to health care advancements over the following decades🤷🏼‍♂️)

Call me crazy 🤪
1800 to 1890

From 43yrs to 50yrs (16% incr) ImageImageImageImage
1890 to 1980

HUGE jump

From 50yrs to 76yrs old (52% incr) ImageImageImageImage
Read 7 tweets
26 Aug 20
#DDDD 💊

Today 4D announce phenomenal trial results for the combination of @Merck's KEYTRUDA with MRx0518 in Lung and Kidney Cancer💥🚨
#DDDD💊

A staggering 42% achieved clinical benefit in a population that had exhausted all other methods of disease/cancer treatment

For a population which has been resistant to all other lines of therapies, this is hugely encouraging... if they can treat the most resistant...
#DDDD💊
...cancers in terminally ill patients, this bodes EXTREMELY well for earlier lines of therapy😬

Also, as the patient population has no other effective treatment this significantly increases the chances of early approval off the back of Phase 2 data
Potentially FDA...
Read 10 tweets
23 Jul 20
#DDDD💊

Why I believe @4dpharmaplc are on the cusp of a multi hundred million pound licencing deal for IBD and IBS?

#DDDD💊

Great Video 'Our Approach' highlighting @4dpharmaplc world leading innovative concept

Harnessing the bodies own Microbiome (Gut Bacteria) to solve genetic imbalances and malfunctions commonly referred to as diseases

4dpharmaplc.com/en/newsroom/vi…
#DDDD💊

Are you excited yet?

Read 96 tweets
23 Jul 20
#DDDD💊

Why I believe @4dpharmaplc are on the cusp of a multi hundred million pound licencing deal for IBD and IBS?
#DDDD💊

Phase 1 data for @4dpharmaplc Blautix's treatment of IBS highlights significant efficacy

-82% Improvement in a reduction of symptoms
-More diverse stable gut bacteria

4dpharmaplc.com/application/fi… ImageImage
#DDDD💊

Interim Safety Data for Blautix Phase 2 larger study shows excellent safety profile

-Comparable to placebo

We are awaiting efficacy data from the Phase 2 study anticipated this Quarter

4dpharmaplc.com/en/newsroom/pr… Image
Read 5 tweets
16 Jul 20
#MXCT

MaxCyte is a cell engineering platform, which uses non viral mRNA for drug development in a wide range of diseases including
-Cancer
-Auto Immune Diseases

11 Commercial Licencing deals with over
-$800m in Milestone Payments Image
#MXCT

MaxCyte is based on their patented novel drug development approach which is Flow Electroporation

Flow Electroporation is reprogramming of Human T-Cells

What this means is they have a machine that can modify any human/patients cells in order to target a specific problem Image
#MXCT

This as I hope you will understand offers enormous potential to address a wide range of therapeutic issues all under the platform which they own
Read 31 tweets
4 May 20
I have substantially bought #DDDD today

I have done extensive research into #COVID19 treatments companies listed on AIM over the weekend (Around 30 HOURS❗❗) and came to the conclusions DDDD is the drug which is most likely to have great efficacy and safety data 💥💥💥
#DDDD

The Microbiome Therapeutics company focused on using an innovative solutions for treatment in unmet 21st century ailments

Areas of focus

-Vaccines
-Oncology (Cancer)
-Respiratory illnesses inc
---SARS-CoV-2 #COVID19
-Irritable Bowel Syndrome
-Central Nervous System
#DDDD 💊

Firstly, I would like to draw your attention towards the extensive co operation between 4D and @Merck

Merck are a $200b company

With the 4th Largest drug in the world 💥

KEYTRUDER®️ (based on $7+ billion Revenues in 2019)

pharmaceutical-technology.com/features/top-s…
Read 51 tweets

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