@Markus_Soeder vergleicht in bekannt manipulativer Weise die Impflicht gegen #Masern mit Corona. Dies ist aus verschiendenen Gründen falsch.

1. Bei den Masern handelt es sich um eine seit Jahrzehnten bewährte Kinderimpfung. Fast alle Pflegekräfte haben diese als Kind gehabt /1
2. Alle, die nach 1970 geboren wurden, sind von der Impfpflicht ausgenommen - man geht davon aus, daß diese die Masern durchgemacht haben.

3. Bleibt eine #Impfflicht für den kleinen Teil der Pflegenden, die jünger sind, die Impfung nicht hatten und keinen Titer nachweisen.

4. es handelt sich also nicht um eine gross angelegte Massenimpfung mit einem Impfstoff von neuarrtiger Beschaffenheit, sondern eher um das Auffüllen einzelner Impflücken.

5. Es ist davon auszugehen, dass geimpfte Corona weitergeben können.

6. Nach allem was wir wissen, ist anders als bei der Lebendimpfung gegen Masern, der Corona-Impstoff sowohl wirksam als auch verträglich in der älteren Bevölkerung.

Der Ansatz wäre also, Hochbetagte freiwillig zu impfen, wenn man diese schützen möchte.

7. Die Sache soll nun von unserem ausgewogenen #Ethikrat vorgelegt werden.

(freindly reminder: Wir haben auch noch ein Parlament.)

/5 & ende

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More from @FrankfurtZack

9 Jan
The countries of South-East Asia are 1000 x better in social distancing than other countries. Interestingly enough, the same is true for the countries of central Africa - they are masters of social distance and measures, too. Image
Nigeria is in the master class of social distancing, too -
5 deaths per Million.

(New Years Eve 2020) Image
It´s all about social distancing.

If you want to learn how to do it right, follow Bangladesh - 43 deaths per Millon.

Maybe this Asian country gets help from some demographic factors, they surely have a low population density and a lot of single households.

(Riots 10/2020) ImageImage
Read 10 tweets
17 Dec 20
Data is overwhelming – lockdowns don´t work.

But, why is that? The concept, in theory, is striking – if we reduce our contacts, we reduce viral spread. This is a no-brainer, isn´t it?

But then, why is data for lockdown so bad?

An important part of the answer in this Thread 👇 Image
What is the concept behind the lockdown idea in detail?

It is based on the assumption that asymptomatic spread is a major contributor to the pandemic.

So lock up the people in their homes! This will stop asymptomatic transmission!

So far, so easy. Image
BUT: most data suggest that asymptomatic transmission is not a major driver of this pandemic.

Nobody knows the exact rate, but let's assume that one asymptomatic patient transmits the virus only to 0.5 Persons, as opposed to 3 Persons when symptomatic.

Read 8 tweets
9 Sep 20
No-Lockdown Uruguay is the blue spot on the red continent below. Positivity Rate is 0,7%; neighboring countries surpass 50%. Plausible?

Uruguay´s success story: They invented their own PCR test. With their own primers, and a Ct value <35. For comparison, CDCs PCR uses Ct <40. Image
We should not compare countries without knowing the "market share" of the test they use. And we have to compare the tests (test-test-reliabilty).

Here is a paper about uruguay´s special response:
Sensitivity and Specifity of the different PCR test are not only defined by different Ct values, but also different primers and gene loci make a big difference.
Read 4 tweets
8 Sep 20
Innate immunity - the strong and fast first layer of our immune response.

Only minutes after entering our body, most -up to 90%- of pathoges are cleared by this "archaic" system.

(to be updated from time to time) Image
Innate immunity destroys structures that are alien to the human organism.

It´s always there, in contrast to B-Cells (Antibodies) and T-Cells it is *not* adaptive.

It does not depend on learning, but on finding structures that are typical of intruders.

Covid19 is a ssRNA Virus with an envelope and a Spike Gylcoprotein, so it has some parts that are very different from human cells.

It should be a rather easy target for innate immunity.

Let´s have a look on some players of this arachaic system in this thread

🧵↕️ Image
Read 4 tweets
29 Aug 20
PCR is prone to contamination by very small amount of viral particles.

Hypothesis: we usually don't notice contamination, especially when it is happening *before* putting the probes into the PCR apparatus. This may even mimick a super spreader event.

Thread with examples

Contamination of a reagent. Not discovered by the laboratory, but by the local health authority which was skeptical about the sudden increase in cases.

Read 24 tweets
11 Jul 20
#Sweden - #Mortality deaths per months 1980-2020

"I think it's like a severe flu season"
Professor Johan Giesecke

(update, putting all charts into one single pinned thread )
#France - deaths per months 1980-2020

In January 2017 more people died than in April 2020. But we saw no TGVs with ICU patients, and had no #crisesainitaire.
#Germany - deaths per months 1990-2020

In 2017/18, Germany was faced with the deadliest flu season of the last 30 years. Nobody took notice. We missed it. @Markus_Soeder did not protect us. And we had plenty of toilet paper.
Read 9 tweets

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