Retrospective analysis:
COVID-19 patients,
n = 91 (aged 74 +/- 13),
2 or more co-morbidities = 54.9%
Given/or not, 400,000 IU vitD
Outcome: transfer to ICU and/or death
The greater the comorbidity burden, the greater effect high-dose vitD treatment mdpi.com/2072-6643/13/1…
COVID-19 patients,
n = 91 (aged 74 +/- 13),
2 or more co-morbidities = 54.9%
Given/or not, 400,000 IU vitD
Outcome: transfer to ICU and/or death
The greater the comorbidity burden, the greater effect high-dose vitD treatment mdpi.com/2072-6643/13/1…
39.6% were treated with vitamin D, based on physician decision.
Results showed significant predictive power of four variables, to response to high-dose vitD:
<50 nmol/L, 25(OH)D
current cigarette smoking
elevated D-dimer
presence of comorbid diseases
Results showed significant predictive power of four variables, to response to high-dose vitD:
<50 nmol/L, 25(OH)D
current cigarette smoking
elevated D-dimer
presence of comorbid diseases
Potential predictive criterion for administrastion of high dose vitamin D (AUC = 0.77, 95% CI: 0.67–0.87, p < 0.0001).
Logistic regression analyses: effectiveness of vitD reliant on comorbidity burden, crude (p = 0.033), propensity score-adjusted analyses (p = 0.039)
Logistic regression analyses: effectiveness of vitD reliant on comorbidity burden, crude (p = 0.033), propensity score-adjusted analyses (p = 0.039)
Results: The greater the comorbidity burden, the greater administration of high-dose vitD would result in a positive outcome
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