🦠 16,840 cases continuing the downward trend (but remember how quickly that exploded from a lower number at the end of the December lock down)

⚰️⚰️⚰️. 1449 (28 day deaths)

⚰️💔 117,378 ONS Stats authority deaths to 22/1/21

⚰️💔⚰️💔 125,223 COVID DEATHS total - an undercount.
Why am I also sure there is an undercount?

Firstly there is a settled pattern in delayed notifications evident from checking deaths by date of death over a period of time. They tick up over a period of two - three weeks.
Secondly if you check the death numbers for 28 day deaths by date of death (eg circled in green) there were 1150 deaths on 22/1/21. The Stats authorities had only been notified of 760 of them

By next week they will have caught up

Thirdly the 28 day death data stops at 31/1/21
VACCINATIONS 💉

YEAH! Over 10 million doses administered.

10,143,511 doses administered to 9,646,715 people

Of those 9,646,715 people 496,796 have received two doses.

350,348 doses administered yesterday.

So Mon and Tues lower than the weekend.
Efficacy data 🙏🙏🙏🙏 on the 1 dose Pfizer in December v 2 dose Pfizer ( 29/12/20 - 10/1/21)

There has been 3-4 weeks since the second dose administered.

What is the relative incidence and severity in the two groups and also compared to NO vaccination cohort of similar age?
I don’t want to get people’s hopes up given 🏥 are still so seriously overloaded and given how quickly we know that trend can reverse, but I think numbers are dropping at a slightly faster rate over the last couple of weeks.

Might that be lockdown + vaccination"

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More from @fascinatorfun

3 Feb
@dgurdasani1 I’m going to tell you a story because you go to a lot of trouble explaining the sources of the evidence as you understand it, identify where there is uncertainty and spell out where you think the evidence is pointing.
@dgurdasani1 Firstly. What you do is both generous in explanation and links to evidence.

And it is brave when others who may be more senior bring their seniority to bear rather than engage in specific details on the particular evidence as an intellectual equal.
@dgurdasani1 When I was a young (and very tiny 7st 7lb) advocate a case came my way that was legally very difficult. Ripping off senile old people - many of their life savings - by offering building and decorating “services” that devalued their properties and grossly overcharged them for it.
Read 17 tweets
3 Feb
🦠19202 new cases but they now count LFT test positives in this number without PCR confirmation
More later

⚰️⚰️⚰️ 1322 (28 day cut off deaths). 1506 (60 day, +ve test & Covid on death certificate)

⚰️💔⚰️💔 126,755 Covid deaths in total - NB an undercount due to notification lag ImageImageImageImage
Tests processed now include HUGE numbers of LFT
2,268,940 in the last 7 days in England
These have a lower sensitivity rate (returning high false negatives) than PCR yet are now lumped in with the positives, without PCR confirmation

It’s the false negatives that are the problem ImageImageImage
Positivity rates are calculated from PCR tests only

But lab based PCR tests processed for P1 and P2 are falling.

So is the reducing Positivity due to people not bothering with PCR test now in much larger numbers, relying on a less sensitive LFT?
Read 10 tweets
2 Feb
Why I became sceptical of the lockdown sceptics | by Dr Michael Fitzpatrick | Jan, 2021 | Medium

An interesting reflection.
mike-93476.medium.com/why-i-became-s…
Instead of engaging with the reality of Covid-19 and the societies which it is ravaging “they have simply used a familiar critique of the politicisation of health and the growth of a culture of fear as a script for explaining the reception of a new virus in new times. “
Neither medical science nor social analysis is sacred
But taking the measure of bureaucratic impositions like lockdowns requires something more too: it requires a moral compass. Government ministers abdicate responsibility for their policies by claiming they ‘follow’ the science
Read 15 tweets
2 Feb
Read this lucid wonderfully readable article by ⁦@liammannix
🇬🇧 UK variant (B.1.1.7)
🇺🇸 South African variant (B.1.351)
🇧🇷 Brazilian variant (P.1)

* Difference between: Mutants, Variants, Strains
* Spike Protein mutations
* Vaccines efficacy smh.com.au/national/what-…
Best article I’ve seen yet

See those orange dots?
That’s the Kent B1.1.7 variant taking over

Seeing the timetable of events (esp late Nov alarm growing at the prevalence of the spike drop out samples tested and that, on 13th Dec we had 21,991 cases ) promoted another look.
Worth bearing in mind now that At the end of the Nov lockdown on 3rd Dec, moving into tiers we had 15,654 cases (by specimen date).

A couple of days at 12/13k & up it went to 21k

33k by 15th December but Johnson doesn’t want to cancel Christmas.

47k by 21st Dec
81k by 28th Dec
Read 24 tweets
1 Feb
52 Days China and the Pandemic 26/12/19
A technician in a private lab in China sequenced a sample from a patient & said it was a bat-SARS like virus.

Wuhan Gov & China CDC were told
They must have known

Meanwhile hospitals in Wuhan were admitting patients with severe pneumonia
Another private lab sequenced another sample and mistakenly said it WAS SARS.

Despite efforts to keep it quiet this information went viral.

Taiwan Social media was alive with rumours before the end of December 2019

By 31 Dec a newsletter went out to 80 million people worldwide
However other scientific intelligence suggested it was associated to SARS but with differences.

The Head of the Chinese CDC, Gao, told and American colleague that it was a new coronavirus but not easily transmissible.

But information was out and he wasn’t believed
Read 24 tweets
1 Feb
Quick summary with usual death data & case processing reporting lag ⚠️ for Sundays & Mondays

General trend downwards.
🦠18,607 new cases (close to 15/12/20)
⚰️ 406 (28 day deaths) BUT
⚰️💔⚰️123,400 Total COVID deaths (ONS to 15/1/21 + 28 day deaths since both by date of death
🏥 Welcome continuing trend downs wards particularly noticeable in England

⤵️ Admissions
⤵️ IN HOSPITAL
⤵️ VENTILATOR beds

Still horribly high numbers but moving in the right direction and faster now.

How much is lockdown & how much vaccination effect?
VACCINATION 💉

9,790,576 shots administered to 9,296,367 people of whom 494,206 have had a second shot.

Excellent effort but - 🙏🙏🙏- efficacy data on the December one shot - two shot cohorts ASAP. Pfizer vaccine group.
Read 4 tweets

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