New Oxford/AstraZeneca #covid19 vaccine pre-print. Pooled analysis of their phase 3 efficacy trials in UK & Brazil + phase 1/2 clinical trials in UK and South Africa.
17,177 volunteers overall
UK: 8,948
Brazil: 6,753
South Africa: 1,476
332 infections >14 days post dose 2
17,177 volunteers overall
UK: 8,948
Brazil: 6,753
South Africa: 1,476
332 infections >14 days post dose 2
Overall vaccine efficacy for Oxford/AZ #covid19 vaccine >14 days after 2nd dose = 66.7%
Complete protection against hospitalization "after 21 day exclusion period." (15 hospitalizations in control group, none in vaccine group.)
Complete protection against hospitalization "after 21 day exclusion period." (15 hospitalizations in control group, none in vaccine group.)
Oxford/AZ report #covid19 vaccine efficacy of 76% with just a single shot, between Days 22 and 90.
Say antibody levels are maintained with minimal waning 3 months out.
Say antibody levels are maintained with minimal waning 3 months out.
Oxford/AZ preprint also goes into data on dose intervals:
2 standard doses 12+ wks apart = VE: 82.4%
2 standard doses <6 wks apart = VE: 54.9%
Binding antibody responses 2x+ higher in 12wk+ vs <6wks in people age 18-55 (what about older?)
Still reading papers.ssrn.com/sol3/papers.cf…
2 standard doses 12+ wks apart = VE: 82.4%
2 standard doses <6 wks apart = VE: 54.9%
Binding antibody responses 2x+ higher in 12wk+ vs <6wks in people age 18-55 (what about older?)
Still reading papers.ssrn.com/sol3/papers.cf…
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