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Meg Tirrell Profile picture
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27 Jan, 5 tweets, 3 min read
Dr Fauci slide on #covid19 vaccines and when results are expected, from first White House Covid-19 response briefing: Image
Dr Fauci slide on coronavirus variants of concern: Image
.@ASlavitt now presenting at WH #COVID19 response briefing. “It’s been a busy 7 days.” Image
.@ASlavitt notes @POTUS is pushing #covid19 team to view 1M shots a day "as a floor, not a ceiling."
.@ASlavitt: plan is to maintain rolling inventory of 2-3 days’ supply of #covid19 vaccine. But passing doses to states very much in real time as they order them. ImageImage

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More from @megtirrell

Meg Tirrell Profile picture
27 Jan
In this new pre-print from the lab of AIDS research pioneer David Ho, suggestions the B.1.35 variant (as expected) has a bigger impact on potency of both antibody drugs and #covid19 vaccines (1)
Neutralizing activity of Moderna & Pfizer vaccines declines only about 2 fold against B.1.1.7 variant, but 8.6 and 6.5 fold against B.1.351, Ho pre-print finds: (2)
On monoclonal antibody activity against the variants (SA9 is B.1.351.), one Regeneron antibody loses potency, but cocktail retains. Lilly single antibody & cocktail appear to lose potency against B.1.351. (Note Regn’s Christos Kyratsous is a co-author on paper) (3)
Read 5 tweets
Meg Tirrell Profile picture
21 Jan
Dr Fauci in the ⁦@WhiteHouse⁩ briefing room
Fauci: If you look at the 7-day avg of cases, right now it looks like it may be plateauing.

But you have to be careful it’s not an artifact of slowing down after the holidays.

“I’m sort of getting deja vu standing up here. I said something like this almost a year ago.”
Fauci: There are always lags so please be aware of that - cases, weeks later hospitalizations, weeks later deaths.

Cases may be plateauing or coming down at the same time hospitalizations and deaths are going up.
Read 11 tweets
Meg Tirrell Profile picture
21 Jan
Exactly one year ago today, @CDCgov confirmed the first case of 2019-nCoV in the U.S.

24M cases later, what are the most important lessons learned, about the virus itself & our response?

10 experts shared their thoughts. A few in a 🧵next: cnbc.com/2021/01/21/cov…
.@DrPaulOffit:

“It is not the winter respiratory virus it was billed to be; it’s far more far-reaching and damaging than that.”
.@CarlosdelRio7:

"More airborne than we originally thought, less surface than we originally thought."

(Remember Clorox-wiping your groceries?)
Read 11 tweets
Meg Tirrell Profile picture
21 Jan
Biden signing 10 executive orders and other directives today on #covid19. Here they are per @WhiteHouse fact-sheet: 🧵

1. EO directing agencies to fix supply of PPE, materials for testing & vaccines, including through Defense Production Act
2. Presidential Memo directing FEMA to increase federal reimbursement to 100% (from 75%) of cost of National Guard personnel & emergency supplies; restoring full reimbursement for eligible costs to support safe school reopening through FEMA Disaster Relief Fund
3. EO to establish Pandemic Testing Board; increase testing capacity by directing use of Defense Production Act; promote surge capacity of testing in the US; onshore test manufacturing, expand public health workforce, support #covid19 screening for schools;ensure equitable access
Read 10 tweets
Meg Tirrell Profile picture
19 Jan
I enjoy the "Mean Girls" parallel of the title of this HBR session about to start: "When Dr Fauci Thinks 'Normal' Will Happen" linkedin.com/video/live/urn…
HBR host notes Dr Fauci got his second dose of Moderna vaccine today
Fauci: If we can get 75-80% of the population of this country fully vaccinated over a period of several months, we will have an umbrella or cloak of herd immunity that would completely turn around the dynamics of the outbreak.
Read 17 tweets
Meg Tirrell Profile picture
16 Jan
Still confused about the 2nd dose vaccine supply? Me too, but I think this is what happened: 🧵

Let’s go chronologically. Last Thursday, governors wrote a letter to @SecAzar requesting second doses not be held in reserve and instead immediately be made available:
2. Friday, CNN reported the Biden team planned to do just that:
3. Tuesday @SecAzar said OWS would make the change as well.

Azar: "We can now ship all of the doses, that had been held in physical reserve with second doses being supplied by doses coming off of manufacturing lines with quality control going forward."

Read 18 tweets

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