I'm still getting a *lot* of media enquiries - more than I can even respond to! So here's some of my best tips for how to reach out to me to maximise your chances of success (though I imagine they're true of other scientists too!)
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(Just as a disclaimer - even if you use all of these, I can't promise I write back, or that I can say yes. If emails slip off the 'front page' of my inbox they basically fall into a black hole 😬. And sometimes I just cannot take any more interviews, even great ones.)
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1. Please tell me what time zone you're in!
If I want to say 'yes' that means a pencilled-in appointment goes into the calendar immediately - so I need to know when you're likely to be awake. If I have to email you to find out... it might not happen.
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2. Please tell me your deadline!
I don't mean your editors deadline or publishing deadline. I mean - do you need to talk to me in 24 hours? By Friday? By next Wednesday? Again, this means I can pencil this in my calendar *straight away* (or at least let you know it's a no).
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(Tip: the more time you give me the better my chance of response. I know that isn't always in journalists' control, but my days fill up fast and last-minute things are often impossible to squeeze in.)
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3. Stand out from the crowd!
I get a lot of the same emails every day: "I'd like to talk to you about the variants."
Why should I pick email 1 over email 2? Ask an interesting question. Show you've done your research. Make me like your email better!
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4. Make it impossible for me not to respond!
Ask me the question nobody's asked me yet & your chances of getting a response shoot up. I spend a lot of my media time repeating myself. Give me a chance to take a new angle or a subject I care a lot about - I can't stop myself!
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As well as the major variants of concern, we can spot a couple of other clusters stemming from an 'old' #SARSCoV2 clade, 19B (originating in late 2019).
19A & 19B haven't been around much since early 2020, as they were overtaken by 20A, B & C (which carry D614G).
2/5
However, a few branches of 19B seem to be popping back up again recently.
In the UK, we can see a recent cluster that's acquired S:E484K (along with other mutations in S).
We're hoping to make this a one-stop location to track not only the 'headline' variants, but many different #SARSCoV2 mutations & variants that scientists are keeping an eye on.
Let's take a tour of the site!
1/12
The buttons on the left will take you to pages focused on key variants & mutations, while the menu at the top will help you jump between info pages (FAQ) & pages compiling together information about many variants (ex: Per country).
Let's take a look at the 20A.EU1 page
2/12
Here, we can
- Click through to a dedicated @Nextstrain build for the variant (1)
- See a list of the defining mutations (2)
- Learn a bit about the variant & see links to papers (3)
- See a distribution of 20A.EU1 per country (4)
- See a protein model! (pic 2)
In the 501Y.V1 (B.1.1.7) variant, here are a few of the non-UK countries with new sequences in this variant, including Denmark, Italy, Spain, France, Portugal, Norway, Germany, the USA, South Kora, & Switzerland, & the UAE, Austria, & Czech Republic for the 1st time
2/18
Denmark has 52 new samples (some yellow), showing both separate introductions and further spread of existing local clusters.
As we head deeper into 2021, a gentle reminder to double-check your #SARSCoV2 sequencing scripts for hardcoded '2020's! 😬
We've seen a real uptick recently in sequences with sampling dates in Jan 2020, with divergence that clearly indicates they meant 2021! 📅🤦🏻♀️
"How can we tell?" you might wonder. Actually, these cases are pretty easy to spot!
Let's take a look at two sequences reported as being from Jan 2020 - 1 in green, 2 in blue. (Spoiler, green is the imposter.)
This view is 'date view' where sequences are plotted on the X-axis by the date they were sampled. Then, we try and infer how they're connected using their genetic information - specifically, what mutations they share & don't share.
3 seqs indicated in red are apparently from the hospital. They're coloured by deletion at position 69, which likely caused them to be flagged (501Y.V1 has it too). However, they're related to other sequences in Germany & Turkey, also w the deletion.
We do see the 69/70 deletion has appeared independently previously. While this is interesting, I don't think it increases concern significantly about this group of sequences, which are part of a larger cluster that's been circulating in Germany since spring 2020.