The #Oxford/#AstraZeneca vaccine has gone through a very tough scrutinizing process.

There are 8 scientific papers (5 on safety) published in peer reviewed journals.

It has now been approved by the UK, European Medicines Agency @EMA_News, @WHO & 22+ other countries.

1/5
2/5
Let's look at some safety data

-Analysis involving 3 trials, 4 countries & 23,848 participants were done
-Followed up for 3.5 months, No deaths
-There was one severe adverse effect, where the patient recovered.

Millions have already been vaccinated.
thelancet.com/journals/lance…
3/5
What side effects were noticed in the trials?

Injection site tenderness (>60%)
Headache, Fatigue (>50%)
Muscle aches (>40%)
Fever,Chills (30%)
Joint pains, Nausea (>20%)

By 7 days, most side effects had resolved.
These side effects are in line with real life vaccinations.
4/5
What are the long term effects?

This we still dont know, as the vaccine is under a year old.

But adverse events are more likely to occur just after the jab, as the vaccine itself does not stay in the body for long.

Also this vaccine technology has been used before.
5/5
Summary
#OxfordVaccine safety

- Large high quality trials, shows vaccine is very safe
- Real life vaccinations have also revealed no severe adverse events
- No vaccine related deaths
- Approved in 40+ countries
- No reason to belive that there are any long term effects

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More from @Rumindahg

8 Jan
#Immunity & #Vaccines
Will try to explain with #GIF's

What is Immunity?
Your Immune system will attack anything unfamiliar. This could be bacteria, virus, fungus or anything it identifies as foreign

When #coronavirus AKA #thevirus infects, our body attacks in two stages
The #firststage is the general response. This is common to any foreign body entering us. Various chemicals are secreted to not only destroy the #thevirus but also to initiate the second stage.

This #firststage is called #Innateimmunity
The #secondstage needs some time to build, as its specific to that particular #thevirus. It takes time because the body needs to figure out which part of the #thevirus to attack & what's needed to attack it. This takes around 6-8 days.

This 2nd stage is #Adaptiveimmunity
Read 14 tweets
30 Dec 20
#PCR test, how to understand the results

First a reminder that the nasal swab for #COVID19 can be negative in a patient infected with covid19. This range is between 5-40%

The #PCR test results are not necessarily a positive or negative scenario. It depends on the Ct value👇
#Ct or cycle threshold is the number of cycles the PCR has to run to get a positive result

Lower the Ct value means higher the viral load & apparently greater the infectivity, severe illness & death

But Ct values vary between machines & even in the same machine due to the user
#Ct values change over the timing of the illness. From high values at onset of symptoms & tailing off after around 5 days. These values might stay on for a long time depending on the patient, even after a live virus is gone. A low value probably means patient is not infectious.
Read 6 tweets

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