Ruminda H. Gunaratne Profile picture
Elderly Medicine | Dementia Research | TH Kalubowila, Sri Lanka | Personal opinions only @CheveningAA @UCLIoN @RCphysicians @ColomboUni @tu_information
Jun 23, 2021 11 tweets 5 min read
#Delta vs #Sinopharm
This will be based on assumption

Summary
Vaccines won't make you immortal

It's individual discipline, vaccination & our governments policies which will ride us out of this wave.

1/
#COVID19SL
#VaccinatedSL The bad news

First, AFAIK there is no data of Sinopharm vs Delta.

We also have real world evidence of break through infections occurring in 🇸🇨🇲🇳🇧🇭

But both of these points can be viewed from a different angle

2/
Jun 21, 2021 8 tweets 2 min read
A lot of fear regarding #Delta, but we should not allow it to engulf us

First, whether its found in Dematagoda or Madiwela its irrelevant

A good guess is that it can be found in other areas & as far as variant epidemiology has shown us it will become the dominant strain
1/ Next, this is not the end of the viral mutation. There are already sublineages of Delta (AY.1) which is causing concern in other parts of the world. We need to understand as long as we give this virus space, it will continue to mutate & evolve into other variants of concern.
2/
Feb 11, 2021 5 tweets 3 min read
The #Oxford/#AstraZeneca vaccine has gone through a very tough scrutinizing process.

There are 8 scientific papers (5 on safety) published in peer reviewed journals.

It has now been approved by the UK, European Medicines Agency @EMA_News, @WHO & 22+ other countries.

1/5 2/5
Let's look at some safety data

-Analysis involving 3 trials, 4 countries & 23,848 participants were done
-Followed up for 3.5 months, No deaths
-There was one severe adverse effect, where the patient recovered.

Millions have already been vaccinated.
thelancet.com/journals/lance…
Jan 8, 2021 14 tweets 15 min read
#Immunity & #Vaccines
Will try to explain with #GIF's

What is Immunity?
Your Immune system will attack anything unfamiliar. This could be bacteria, virus, fungus or anything it identifies as foreign

When #coronavirus AKA #thevirus infects, our body attacks in two stages The #firststage is the general response. This is common to any foreign body entering us. Various chemicals are secreted to not only destroy the #thevirus but also to initiate the second stage.

This #firststage is called #Innateimmunity
Dec 30, 2020 6 tweets 3 min read
#PCR test, how to understand the results

First a reminder that the nasal swab for #COVID19 can be negative in a patient infected with covid19. This range is between 5-40%

The #PCR test results are not necessarily a positive or negative scenario. It depends on the Ct value👇 #Ct or cycle threshold is the number of cycles the PCR has to run to get a positive result

Lower the Ct value means higher the viral load & apparently greater the infectivity, severe illness & death

But Ct values vary between machines & even in the same machine due to the user