To clarify
The "scientist" who knows about WIV deleted databases, who blocked anyone who asked about them for months, who admits he knows what is in them, who knows all about WIV work that could have led to a lab leak, is the guy put in charge of 2 "investigations" (Lancet & WHO)
I kept on wondering over the last year how come so many people of interest work at Lindsley F. Kimball Research Institute, New York Blood Center ncbi.nlm.nih.gov/pmc/articles/P…
like Shibo Jiang @Rossana38510044
and Lanying Du
An H5N1 M2e-based multiple antigenic peptide vaccine confers heterosubtypic protection from lethal infection with pandemic 2009 H1N1 virus link.springer.com/article/10.118…
From the paper referenced by Daszak
"available antibodies and vaccines based on SARS-CoV RBD will not protect the next SARS-like disease caused by bat SL-CoV SHC014 strain"
Can @peterdaszak tell us exactly what follow up work in humanised mice was done on the:
"further development of effective vaccines and treatments for potential infection by the SL-CoV strains, as represented by SHC014"
• • •
Missing some Tweet in this thread? You can try to
force a refresh
1. Mass Vaccination in a Pandemic - Benefits versus Risks: Interview with Geert Vanden Bossche
sub optimal vaccine immune response leading to viral variance explains why first 3 variants occurred in 3 countries where vaccines were tested, Brazil, UK & SA
2. This interview will make better sense if you read first his open letter "Halt All Covid-19 Mass Vaccination Immediately" (Open Letter to the WHO): dryburgh.com/geert-vanden-b…
Scroll down for letter to WHO
3. GVB warns of complete disaster:
We must halt all ongoing Covid-19 mass vaccination campaigns as a temporary health benefit to the most vulnerable groups does not justify a public health
disaster of international concern. dryburgh.com/wp-content/upl…
Compilation Thread on ORF8 ORF8 or Fate? 1. ZLS (2018):
"Considering the variability of orf8 in bats, civets and humans, investigating the function of orf8 is a priority, particularly the contribution of these different variants to viral pathogenesis."
2. ORF8 or Fate?
"In addition to receptor binding, proteolytic cleavage of S & potentially other mutations that affect virion & trimer stability may be important for virus transmissibility in different hosts, & these factors need to be studied further." nature.com/articles/s4157…
3. ORF8 or Fate?
Overwhelmingly these viruses had mutations or
29 deletions in ORF8 - associated with reduced replicative fitness of the virus.. may be associated with host adaptation
via @CarltheChippy
382-nt deletion during early evolution of SARS-CoV biorxiv.org/content/10.110…
(A and B Sequence & structural properties of insert PRRA (D) Sequence similarity between close neighborhood of PRRA insert, neurotoxin motifs Y674QTQTNSPRRAR685, homologous to Ophiophagus (cobra) & Bungarus genera & 3 RABV strains & HIV-1 gp120 superantigenic motif in last row
Study on Ribonuclease From Snake Venom of Zhejiang Cobra (Naja naja atra)
ZHANG Gon-jin
Wuhan Institute of Virology,Academia Sinica zoores.ac.cn/article/id/1281
2. Common Contaminants in NGS
Until an effective strategy is found to eliminate contaminants from sequencing runs, novel sequences detected in such runs should be scrutinized by qPCR analysis to ensure they originate from specimens rather than the lab journals.plos.org/plosone/articl…