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Eric Feigl-Ding Profile picture
@DrEricDing
Mar 21, 2021 • 34 tweets • 19 min read • Read on X
PAY ATTENTION—There is one crisis we all needs to pay attention to—and that is the unprecedented Brazil 🇧🇷 surge of the #P1 variant, overloaded hospitals, & sharp mortality spike. If more contagious #P1 out of control worldwide, we are all endangered. 🧵

#SOSBrazil #COVID19 ImageImage
2) I cannot overemphasis how serious the crisis in Brazil is. It is virtually impossible to find any ICU bed, and many hospitals running out of sedative medications to perform intubation with—so doctors are intubating without any analgesic meds. Hospitals are in collapse.
3) I’m not exaggerating that hospitals in Brazil are in collapse. This is the headline of a major newspaper. Image
4) Don’t just listen to me. Listen to the reporting on the ground. This report was filed last week by @MattRiversCNN — he says it has gotten only worse.

5) Nobody can deny the pandemic when hospitals are completely overrun. Don’t let anyone dismiss #COVID19 and what is happening in Brazil - hospitalizations and deaths DO NOT LIE. Image
6) The crisis is described by the @fiocruz @fiocruz_en foundation as the **worst sanitation and hospital collapse in the history of Brazil** Image
7) I’m told by reporters that even “we're also hearing very consistently, that in Brazil more and more young people are dying on the virus. doctors keep telling us that their patients keep getting younger, no comorbidities” - from doctors across many cities. @MattRiversCNN
8) But also more concerning — Brazil experts analysis says P1 is potentially 2-2.5x faster transmission (more contagious) than the old common strains. That means it is also faster than #B117 sweeping the world.

We need to get serious about Brazil crisis. ?
9) Another Brazil research group puts #P1 transmission at 2x faster than old strain (instead of 2.5x above), but they estimate a way worse whopping 25-60% reinfection rate. That’s serious.

bbc.com/news/amp/healt… Image
10) How good is are the mRNA vaccines against this #P1 variant menace? Only semi— it has moderate neutralization- better than the SA #B1351, but worse than #B117 (which responds well to vaccine).

FYI earlier Pfizer-conducted study said okay, but this bigger study disagrees.
11) But the problem for Brazil is that it doesn’t have the mRNA vaccines. It has the AstraZeneca and SinoVac vaccine. We don’t know the exact efficacy yet for #P1, but SinoVac vaccine showed a much lower 50% efficacy in Brazil trials, before P1.

google.com/amp/s/www.bbc.…
12) Now 50% is still good, and for severe disease, it’s 78% for SinoVac, so that’s decent.

J&J vaccine shows mid to upper 80% for Brazil, but J&J isn’t available in Brazil yet either.

Main problem is Brazil doesn’t have enough! google.com/amp/s/amp.cnn.…
13) state of Rio de Janeiro suspended its vaccination campaign because it had run out of vaccine supplies.

"This is a disaster, a total disaster," a woman told CNN after being denied her vaccine. "Who is to blame for all this? I think our leaders, our politicians suck."
14) “less than 10 million people in the country of about 220 million had received at least one dose, according to federal health data. Only 1.57% of the population had been fully vaccinated.”

THIS IS AN EPIC DISASTER in the making for Brazil. google.com/amp/s/amp.cnn.…
15) How the hell did Brazil screw up its vaccine supply so much?

“multiple experts say the ineptitude of the federal government, led by Covid-skeptic Bolsonaro, has sabotaged. They point to a distinct lack of urgency on the fed govt to secure supplies”
cnn.com/2021/02/01/ame…
16) Brazil is in talks with the US to import some vaccines. The US already “loaned” 4 million doses to Mexico & Canada. But the talks with Brazil started March 13th and still have not reached any deal. Brazil needs it soon. Hope Bolsonaro is playing ball.
google.com/amp/s/www.voan…
17) Even with vaccine imports, and the delay in rollout and immunity kicking in, the next month will be brutal for Brazil. We might see what unmitigated full onslaught with a downplaying Bolsonaro looks like.

Meantime, Brazil ordering 3x the coffins.

metropoles.com/brasil/covid-a…
18) But I also want to offer a message of hope to the people of Brazil 🇧🇷— the world sees your struggle and your pain. I talk to colleagues at the WHO and in DC. The world has not forgotten you—even if your leader maybe sometimes has. The world needs to care and does care.
19) Meantime, Bolsonaro is the one person that world leaders need to call out and pressure. He is literally stopping all efforts to improve the situation. This is untenable.

If this Brazil crisis keeps going, I worry for its stability. google.com/amp/s/amp.cnn.… Image
20) I don’t believe in doomed fate. “There is no fate but what we make.”

Brazil needs help, Brazil needs change. Brazil needs leadership that will put human lives first, and to end suffering of its poor.

May God & the world help the people of Brazil.
21) To the rest of the 🌎—please don’t be selfishly withholding aid/vaccines. If Brazil’s #P1 crisis grows, so will the risk for the world. We rise as fall as one planet & civilization. We need to remember the motto—“All for one, one for all”—let’s all find our inner humanity. 🙏
22) p.s. the Oxford-AstraZeneca reported to be is efficacious against the #P1 variant. But the study hasn’t be released yet by researchers - details forthcoming.

US has a stockpile over over 30 million doses of AstraZeneca—it needs to release now.
cnbc.com/2021/03/05/oxf…
23) UK Imperial team:

⚠️“data show #P1 variant is 1.4-2.2 times more transmissible than other variants & original #SARSCoV2 strain, and 25%-65% more likely to evade existing protective immunity from previous non-P.1 infections—susceptible to reinfection.”
edition.cnn.com/world/live-new… Image
24) The catastrophe in Brazil is the worst in its history. And likely will be the worst in the annals of this pandemic — we desperately need to urgently send aid and vaccines to Brazil 🇧🇷.

Please help @WHCOS @aslavitt46 @ASlavitt @JeffZients @DrTedros @mvankerkhove @gabbystern
25) good news - vaccine deals inked by Brazil to buy more.

Bad news—most of the vaccines ordered aren’t coming for many many months.
26) Vaccine inequality is the great inequality that will lead to more tragedy in this pandemic.

We need to send vaccines urgently to Brazil, Mexico, and all of Latin America. #COVID19 #COVID19Vaccine

(HT @fibke) Image
27) The longer we neglect to vaccinate low and middle income countries (LMIC), the longer this crisis will continue.

#VaccinEquity for Brazil and all of Latin America and Africa and Asia.

(Ht @fibke)

pandem-ic.com/vaccine-equity… Image
28) ...I’m hearing some signals US might help Brazil hospitals in some potential ways soon. Unclear what yet. But there are some in WH that are exploring. Fingers crossed of what’s to come.
29) this was Brazil 3 days ago... and those spikes have now surged even more.
30) Now Brazil’s #P1 crisis has spilled over into neighboring countries...
31) And now #P1 has invaded North America - British Columbia 🇨🇦 has a recent sudden surge of #P1.
32) The Brazilian 🇧🇷 #P1 epidemic has now definitively spilled into other countries and caused outbreaks—the largest being in British Columbia, Canada.
33) P.s. small update on Brazil 🇧🇷 situation - I have receive word that Brazil is now engaging with the US directly. Hopeful 🙏
34) Brazil needs to act fast.... now more young people are dying than in first wave.

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More from @DrEricDing

Eric Feigl-Ding Profile picture
Nov 13
⚠️BREAKING—ICU Hospitalized human bird flu case in Canada now officially confirmed as H5N1. Worse, it is the same 2.3.4.4b virus clade (variant group) as the one found in BC🇨🇦 poultry and in Washington state🇺🇸! The hospitalized teenager (with no pre existing conditions) had no animal contact, does not live on farm, had “deterioration quite rapid” and now critical in ICU with ARDS. Canada officials says infectious period is 2 days **prior to symptoms** (ie asymptomatic transmission) and infectious up to 10 days.Image
2) Public Health Agency of Canada's National Microbiology Laboratory (NML) in Winnipeg confirmed that the individual has avian influenza H5N1
canada.ca/en/public-heal…
3) details…

⚠️BAD UPDATE—BIRD FLU HOSPITALIZATION IN CANADIAN TEEN

Summary 🧵 of the live press conference with Canada’s British Columbia health officer.

📌The teen is in intensive care.
📌Condition is ARDS
📌Teen was healthy prior; no underlying conditions

bsky.app/profile/dreric…
Read 4 tweets
Eric Feigl-Ding Profile picture
Nov 13
Trump’s incoming SECRETARY OF DEFENSE who doesn’t wash his hands and doesn’t believe in germs. Image
2) Trump’s new SECDEF is also in favor of committing war crimes. businessinsider.com/pete-hegseth-a…
3) Trump’s SECDEF pick is a wild character. And loves hawking merch.
Read 4 tweets
Eric Feigl-Ding Profile picture
Nov 9
My god—Google Search for “what is a tariff” sudden spikes the DAY AFTER ELECTION DAY. 🤦🏻‍♂️ Image
2) many folks simply don’t understand what a tariff is — unless you explain it several times to them with analogies. Even then, it’s hard for many to grasp. Eg 👇
3) Ah shit… it’s now gotten worse. Why do so many people do their hw late??,
Read 6 tweets
Eric Feigl-Ding Profile picture
Nov 6
📍HARRIS IS STILL AHEAD IN PA—in terms of votes yet to be counted. She’s still +2 of what is needed to win PA, given the outstanding votes still remaining in PA cities, according to @CBSNews @NorahODonnell Image
Image
Image
Harris has enough remaining in PA Philly suburbs to still win. Image
3) folks. The NYT needle is not reliable.
Read 5 tweets
Eric Feigl-Ding Profile picture
Oct 31
Plastic cookware should not be used. Period. Especially BLACK PLASTIC cookware, that often mixes in toxic recycled electronic waste materials. DISPOSE OF ALL PLASTIC COOKWARE, especially if black colored plastic ones. Pass it on to your family.

Gift🎁🔗
theatlantic.com/health/archive…Image
2) Because optical sensors in recycling facilities can’t detect them, black-colored plastics are largely rejected from domestic-waste streams, resulting in a shortage of black base material for recycled plastic. So the demand for black plastic appears to be met “in no insignificant part” via recycled e-waste, according to Turner’s research. TV and computer casings, like the majority of the world’s plastic waste, tend to be recycled in informal waste economies with few regulations and end up remolded into consumer products, including ones, such as spatulas and slotted spoons, that come into contact with food.
3) You simply do not want flame retardants anywhere near your stir-fry. Flame retardants are typically not bound to the polymers to which they are added, making them a particular flight risk: They dislodge easily and make their way into the surrounding environment. And, indeed, another paper from 2018 found that flame retardants in black kitchen utensils readily migrate into hot cooking oil. The health concerns associated with those chemicals are well established: Some flame retardants are endocrine disruptors, which can interfere with the body’s hormonal system, and scientific literature suggests that they may be associated with a range of ailments, including thyroid disease, diabetes, and cancer. People with the highest blood levels of PBDEs, a class of flame retardants found in black plastic, had about a 300 percent increase in their risk of dying from cancer compared with people who had the lowest levels, according to a study released this year. In a separate study, published in a peer-reviewed journal this month, researchers from the advocacy group Toxic-Free Future and from Vrije Universiteit Amsterdam found that, out of all of the consumer products they tested, kitchen utensils had some of the highest levels of flame retardants.
Read 4 tweets
Eric Feigl-Ding Profile picture
Oct 29
⚠️MASK MANDATE RETURNING TO ALL NIH PATIENT CLINICS—Effective November 4, 2024, masking will be required in all patient care & waiting rooms. Furthermore, testing for COVID, flu A, flu B, and RSV will be required for all inpatients & rooming-in visitors.
cc.nih.gov/patient-servic…Image
Image
2) This means wearing a mask will be REQUIRED in all patient care areas, including waiting rooms. ➡️This change is due to an anticipated increase in COVID-19 and other respiratory virus activity in the community. 😷
3) I think people should stock up on COVID tests again. The Cheapest COVID test on the U.S. market is now as low as $1.50 with special promo code “COV20”… expiring Jan or March 2025.

store.pharmalynk.com/products/advin…Image
Read 6 tweets

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