Navajo Nation President Jonathan Nez thanked the Navajo people, health care workers, frontline workers and others “Once again, the Navajo Nation is exemplifying what can be accomplished when we listen to the public health experts and work together."
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In Germany, as a new increase in cases accelerates one month after a minimum that was not very low, Chancellor Merkel points to presence of the UK variant as a new pandemic, more lethal, with more and longer transmission.
Germany extended current restrictions through April 18, and adds 5 days of shutdown for Easter. Easter restrictions will be stricter than before. Almost all shops, including grocery stores, have to close.
Brazil is also in a new pandemic with the even more deadly, and more rapidly spreading P.1 variant, which continues to set records for daily new deaths. Nearly every Brazilian state has ICU occupancy at or above 80%.
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Vaccination is not playing a major role with less than 4.5% of the population having one or two shots, and there is evidence of immune evasion for reinfection so there is concern about the vaccine as well.
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Local leaders want to impose restrictions, but federal authorities insist on keeping businesses open.
In the past month, US effective reproduction number (Rt) has risen from 0.78 (historical low), back up above R=1.
Why is Rt rising? We keep relaxing restrictions, and new variants are accelerating transmission even as vaccinations are happening
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This shows up in case counts, where the recent decline in cases has reversed and cases are now growing. With reopening across the country, as well as new variants, growth will accelerate into a “4th wave”
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Vaccinations shouldn't be expected to be a get-out-of-jail-free card in ending the pandemic. New variants not only accelerate transmission, they can undermine immunity of prior infection and vaccination. The best strategy is to aim for elimination using vaccination to help.
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Three main identified “variants of concern” with more rapid transmission, higher severity, and vaccine evasion have spread globally in recent months because travel restrictions were not sufficiently strong. Each can be considered like a new pandemic.
A new P.3 variant first found in Philippines has E484K spike protein mutation found in Brazilian P1 variant, associated to stronger receptor binding and lower vaccine efficacy, and the N501Y mutation found in the UK B117 variant also considered to increase transmissibility.
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And....🥁...😬
Two cases of the Philippines P.3 variant have been detected in the UK.
Without travel restrictions the worst variants are everywhere. [When will they learn?]
India reported the year’s biggest daily increase in cases on Sunday, with 25,320 new cases. Maharashtra, the epicenter of the renewed surge is imposing new restrictions but not a new lockdown. Halfway measures are not sufficient for this pandemic.