Best V3 news for today (vaccine-virus-variants)👍
1. Prior covid + mRNA vaccine (@BioNTech_Group) -> very high levels of neutralizing antibodies against B.1.351 (South Africa) and P.1 (Brazil) variants @NEJM (N=6)
nejm.org/?query=feature…
1. Prior covid + mRNA vaccine (@BioNTech_Group) -> very high levels of neutralizing antibodies against B.1.351 (South Africa) and P.1 (Brazil) variants @NEJM (N=6)
nejm.org/?query=feature…
2. The mRNA vaccine (@moderna_tx) and @Novavax elicit high levels of neutralizing antibodies versus the B.1.429 (California) variant, similar to B.1.17 (UK) which means not very much immune evasion @NEJM nejm.org/doi/full/10.10…
3. Neutralizing antibodies against the B.1.351 (South African, 501Y.V2) variant cross-react to the others, telling us if we need a booster vaccine by incorporating this code, it should be quite effective (501Y.V3 = P.1, Brazil) @NEJM
nejm.org/doi/full/10.10…
nejm.org/doi/full/10.10…
4. Why is this all very good news?
—Prior covid is like the 1st shot, a primer for the immune response
—1st data in patients with mRNA vaccine vs. B.1.351 and P.1 and they look very solid (small N) for very high levels of neutralizing antibodies
—California variant responds well
—Prior covid is like the 1st shot, a primer for the immune response
—1st data in patients with mRNA vaccine vs. B.1.351 and P.1 and they look very solid (small N) for very high levels of neutralizing antibodies
—California variant responds well
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